Search Results - "Jacobsen, D."

Dehydration melting at the top of the lower mantle by Schmandt, Brandon, Jacobsen, Steven D., Becker, Thorsten W., Liu, Zhenxian, Dueker, Kenneth G.

“…The high water storage capacity of minerals in Earth's mantle transition zone (410- to 660-kilometer depth) implies the possibility of a deep H2O reservoir,…”
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Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era by Goyal, Gaurav, Heaney, Mark L., Collin, Matthew, Cohen-Aubart, Fleur, Vaglio, Augusto, Durham, Benjamin H., Hershkovitz-Rokah, Oshrat, Girschikofsky, Michael, Jacobsen, Eric D., Toyama, Kazuhiro, Goodman, Aaron M., Hendrie, Paul, Cao, Xin-xin, Estrada-Veras, Juvianee I., Shpilberg, Ofer, Abdo, André, Kurokawa, Mineo, Dagna, Lorenzo, McClain, Kenneth L., Mazor, Roei D., Picarsic, Jennifer, Janku, Filip, Go, Ronald S., Haroche, Julien, Diamond, Eli L.

“…Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a neoplastic disorder owing to the discovery of recurrent activating MAPK…”
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A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress by Geib, Elena, Gressler, Markus, Viediernikova, Iuliia, Hillmann, Falk, Jacobsen, Ilse D, Nietzsche, Sandor, Hertweck, Christian, Brock, Matthias

“…Melanins are ubiquitous pigments found in all kingdoms of life. Most organisms use them for protection from environmental stress, although some fungi employ…”
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Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma by Neelapu, Sattva S, Locke, Frederick L, Bartlett, Nancy L, Lekakis, Lazaros J, Miklos, David B, Jacobson, Caron A, Braunschweig, Ira, Oluwole, Olalekan O, Siddiqi, Tanya, Lin, Yi, Timmerman, John M, Stiff, Patrick J, Friedberg, Jonathan W, Flinn, Ian W, Goy, Andre, Hill, Brian T, Smith, Mitchell R, Deol, Abhinav, Farooq, Umar, McSweeney, Peter, Munoz, Javier, Avivi, Irit, Castro, Januario E, Westin, Jason R, Chavez, Julio C, Ghobadi, Armin, Komanduri, Krishna V, Levy, Ronald, Jacobsen, Eric D, Witzig, Thomas E, Reagan, Patrick, Bot, Adrian, Rossi, John, Navale, Lynn, Jiang, Yizhou, Aycock, Jeff, Elias, Meg, Chang, David, Wiezorek, Jeff, Go, William Y

“…In 101 patients with refractory large B-cell lymphoma, anti-CD19 chimeric antigen receptor (CAR) T-cell therapy (axicabtagene ciloleucel) resulted in an…”
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Ventricular arrhythmias and sudden death in patients taking ibrutinib by Lampson, Benjamin L., Yu, Lijian, Glynn, Robert J., Barrientos, Jacqueline C., Jacobsen, Eric D., Banerji, Versha, Jones, Jeffrey A., Walewska, Renata, Savage, Kerry J., Michaud, Gregory F., Moslehi, Javid J., Brown, Jennifer R.

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Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma by Shanmugam, Vignesh, Griffin, Gabriel K., Jacobsen, Eric D., Fletcher, Christopher D. M., Sholl, Lynette M., Hornick, Jason L.

“…Recent studies have demonstrated recurrent activating mutations involving the classical MAPK and PI3K signaling pathways in a large proportion of histiocytic…”
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Spatial and temporal variation of benthic macroinvertebrate assemblages during the glacial melt season in an Italian glacier-fed stream by Scotti, A., Jacobsen, D., Tappeiner, U., Bottarin, R.

“…The biodiversity of glacier-fed streams is particularly threatened by climate change, emphasising the need of monitoring these sentinel systems. The…”
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Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes by Schwarzmüller, Tobias, Ma, Biao, Hiller, Ekkehard, Istel, Fabian, Tscherner, Michael, Brunke, Sascha, Ames, Lauren, Firon, Arnaud, Green, Brian, Cabral, Vitor, Marcet-Houben, Marina, Jacobsen, Ilse D, Quintin, Jessica, Seider, Katja, Frohner, Ingrid, Glaser, Walter, Jungwirth, Helmut, Bachellier-Bassi, Sophie, Chauvel, Murielle, Zeidler, Ute, Ferrandon, Dominique, Gabaldón, Toni, Hube, Bernhard, d'Enfert, Christophe, Rupp, Steffen, Cormack, Brendan, Haynes, Ken, Kuchler, Karl

“…The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis, causing infections ranging from superficial to life-threatening…”
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Fungal-Bacterial Interactions in Health and Disease by Krüger, Wibke, Vielreicher, Sarah, Kapitan, Mario, Jacobsen, Ilse D, Niemiec, Maria Joanna

“…Fungi and bacteria encounter each other in various niches of the human body. There, they interact directly with one another or indirectly via the host…”
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Forest buffer-strips mitigate the negative impact of oil palm plantations on stream communities by Rojas-Castillo, O.A., Kepfer-Rojas, S., Vargas, N., Jacobsen, D.

“…The global area cultivated with oil palm has doubled in the past two decades, causing deforestation, land-use change, freshwater pollution, and species loss in…”
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HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus by Schrettl, Markus, Beckmann, Nicola, Varga, John, Heinekamp, Thorsten, Jacobsen, Ilse D, Jöchl, Christoph, Moussa, Tarek A, Wang, Shaohua, Gsaller, Fabio, Blatzer, Michael, Werner, Ernst R, Niermann, William C, Brakhage, Axel A, Haas, Hubertus

“…Iron is essential for a wide range of cellular processes. Here we show that the bZIP-type regulator HapX is indispensable for the transcriptional remodeling…”
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Thermoelastic Properties of Fe3+‐Rich Jeffbenite and Application to Superdeep Diamond Barometry by Qin, Fei, Wang, Fei, Smyth, Joseph R., Zhang, Dongzhou, Xu, Jingui, Jacobsen, Steven D.

“…Jeffbenite (Mg3Al2Si3O12) is a tetragonal phase found in so far only in superdeep diamonds, and its thermoelastic parameters are a prerequisite for determining…”
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The protein kinase Ire1 has a Hac1-independent essential role in iron uptake and virulence of Candida albicans by Ramírez-Zavala, Bernardo, Krüger, Ines, Dunker, Christine, Jacobsen, Ilse D, Morschhäuser, Joachim

“…Protein kinases play central roles in virtually all signaling pathways that enable organisms to adapt to their environment. Microbial pathogens must cope with…”
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Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers by Allert, Stefanie, Förster, Toni M, Svensson, Carl-Magnus, Richardson, Jonathan P, Pawlik, Tony, Hebecker, Betty, Rudolphi, Sven, Juraschitz, Marc, Schaller, Martin, Blagojevic, Mariana, Morschhäuser, Joachim, Figge, Marc Thilo, Jacobsen, Ilse D, Naglik, Julian R, Kasper, Lydia, Mogavero, Selene, Hube, Bernhard

“…Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and…”
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A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma by Witzig, T E, Reeder, C B, LaPlant, B R, Gupta, M, Johnston, P B, Micallef, I N, Porrata, L F, Ansell, S M, Colgan, J P, Jacobsen, E D, Ghobrial, I M, Habermann, T M

“…The phosphatidylinositol 3-kinase signal transduction pathway members are often activated in tumor samples from patients with non-Hodgkin's lymphoma (NHL)…”
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Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments by Matthias, Julia, Heink, Sylvia, Picard, Felix, Zeiträg, Julia, Kolz, Anna, Chao, Ying-Yin, Soll, Dominik, de Almeida, Gustavo P, Glasmacher, Elke, Jacobsen, Ilse D, Riedel, Thomas, Peters, Anneli, Floess, Stefan, Huehn, Jochen, Baumjohann, Dirk, Huber, Magdalena, Korn, Thomas, Zielinski, Christina E

“…Th cells integrate signals from their microenvironment to acquire distinct specialization programs for efficient clearance of diverse pathogens or for…”
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Stress adaptation in a pathogenic fungus by Brown, Alistair J P, Budge, Susan, Kaloriti, Despoina, Tillmann, Anna, Jacobsen, Mette D, Yin, Zhikang, Ene, Iuliana V, Bohovych, Iryna, Sandai, Doblin, Kastora, Stavroula, Potrykus, Joanna, Ballou, Elizabeth R, Childers, Delma S, Shahana, Shahida, Leach, Michelle D

“…Candida albicans is a major fungal pathogen of humans. This yeast is carried by many individuals as a harmless commensal, but when immune defences are…”
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Fungal infections in animals: a patchwork of different situations by Seyedmousavi, Seyedmojtaba, Bosco, Sandra de M G, de Hoog, Sybren, Ebel, Frank, Elad, Daniel, Gomes, Renata R, Jacobsen, Ilse D, Martel, An, Mignon, Bernard, Pasmans, Frank, Piecková, Elena, Rodrigues, Anderson Messias, Singh, Karuna, Vicente, Vania A, Wibbelt, Gudrun, Wiederhold, Nathan P, Guillot, Jacques

“…Abstract The importance of fungal infections in both human and animals has increased over the last decades. This article represents an overview of the…”
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Fungal infection strategies by Jacobsen, Ilse D.

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Candida albicans scavenges host zinc via Pra1 during endothelial invasion by Citiulo, Francesco, Jacobsen, Ilse D, Miramón, Pedro, Schild, Lydia, Brunke, Sascha, Zipfel, Peter, Brock, Matthias, Hube, Bernhard, Wilson, Duncan

“…The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts is critical for pathogenesis. Here we report endothelial zinc…”
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