Search Results - "Jacobs‐Lorena, M."

Storage and secretion of the peritrophic matrix protein Ag-Aper1 and trypsin in the midgut of Anopheles gambiae by Devenport, M, Fujioka, H, Jacobs-Lorena, M

“…The gene Ag-Aper1 encodes a peritrophic matrix (PM) protein from the mosquito Anopheles gambiae. Ag-Aper1 gene expression and protein localization in the…”
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Driving midgut-specific expression and secretion of a foreign protein in transgenic mosquitoes with AgAper1 regulatory elements by Abraham, E.G, Donnelly-Doman, M, Fujioka, H, Ghosh, A, Moreira, L, Jacobs-Lorena, M

“…The Anopheles gambiae adult peritrophic matrix protein 1 (AgAper1) regulatory elements were used to drive the expression of phospholipase A2 (PLA2), a protein…”
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Expression of a mutated phospholipase A₂ in transgenic Aedes fluviatilis mosquitoes impacts Plasmodium gallinaceum development by Rodrigues, F.G, Santos, M.N, de Carvalho, T.X.T, Rocha, B.C, Riehle, M.A, Pimenta, P.F.P, Abraham, E.G, Jacobs-Lorena, M, Alves de Brito, C.F, Moreira, L.A

“…The genetic manipulation of mosquito vectors is an alternative strategy in the fight against malaria. It was previously shown that bee venom phospholipase A₂…”
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The peritrophic matrix limits the rate of digestion in adult Anopheles stephensi and Aedes aegypti mosquitoes by Villalon, J.M., Ghosh, A., Jacobs-Lorena, M.

“…The peritrophic matrix (PM) is a chitin-containing acellular sheath that surrounds the blood meal and separates the food bolus from the midgut epithelium…”
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Developmental Regulation of bicoid mRNA Stability Is Mediated by the First 43 Nucleotides of the 3′ Untranslated Region by P. Surdej, M. Jacobs-Lorena

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Aedes aegypti transducing densovirus pathogenesis and expression in Aedes aegypti and Anopheles gambiae larvae by Ward, T. W, Jenkins, M. S, Afanasiev, B. N, Edwards, M, Duda, B. A, Suchman, E, Jacobs‐Lorena, M, Beaty, B. J, Carlson, J. O

“…Aedes aegypti densovirus (AeDNV) is a small DNA virus that has been developed into an expression and transducing vector for mosquitoes [Afanasiev et al. (1994)…”
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Characterization of a carboxypeptidase A gene from the mosquito, Aedes aegypti by Edwards, M. J., Moskalyk, L. A., Donelly-Doman, M., Vlaskova, M., Noriega, F. G., Walker, V. K., Jacobs-Lorena, M.

“…A gut‐specific carboxypeptidase A gene (AeCPA) from the mosquito, Aedes aegypti, was cloned and characterized. The gene has an open reading frame that predicts…”
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The Anopheles gambiae adult midgut peritrophic matrix proteome by Dinglasan, R.R., Devenport, M., Florens, L., Johnson, J.R., McHugh, C.A., Donnelly-Doman, M., Carucci, D.J., Yates, J.R., Jacobs-Lorena, M.

“…Malaria is a devastating disease. For transmission to occur, Plasmodium, the causative agent of malaria, must complete a complex developmental cycle in its…”
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Peritrophic matrix proteins of Anopheles gambiae and Aedes aegypti by Moskalyk, L A, Oo, M M, Jacobs-Lorena, M

“…Little is known about the composition and function of the mosquito peritrophic matrix (PM), a physical barrier that pathogens must traverse to complete their…”
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A gut-specific serine protease from the malaria vector Anopheles gambiae is downregulated after blood ingestion by Shen, Z., Edwards, M. J., Jacobs-Lorena, M.

“…A chymotrypsin‐like serine protease gene (AgChyL) was cloned from the mosquito Anopheles gambiae by a polymerase chain reaction (PCR)‐based subtractive cDNA…”
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Targeting essential Eimeria ninakohlyakimovae sporozoite ligands for caprine host endothelial cell invasion with a phage display peptide library by Ruiz, A., Pérez, D., Muñoz, M C, Molina, J M, Taubert, A., Jacobs-Lorena, M., Vega-Rodríguez, J., López, A M, Hermosilla, C.

“…Eimeria ninakohlyakimovae is an important coccidian parasite of goats which causes severe diarrhoea in young animals. Specific molecules that mediate E…”
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DNA puff gene BhC4-1 of Bradysia hygida is specifically transcribed in early prepupal salivary glands of Drosophila melanogaster by Monesi, N, Jacobs-Lorena, M, Paco-Larson, M.L

“…The BhC4-1 gene of the sciarid Bradysia hygida is located at DNA puff C4 and is amplified and actively transcribed in the salivary gland at the end of the last…”
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Gut-specific genes from the black fly Simulium vittatum encoding trypsin-like and carboxypeptidase-like proteins by Ramos, A, Mahowald, A, Jacobs-Lorena, M

“…In haematophagous insects digestion of the blood meal provides nutrients for survival and essential components for egg production. We have isolated and…”
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A Drosophila third chromosome Minute locus encodes a ribosomal protein by Andersson, S, S{aelig}b{oslash}e-Larssen, S, Lambertsson, A, Merriam, J, Jacobs-Lorena, M

“…Minutes (M) are a group of over 50 phenotypically similar Drosophila mutations widely believed to affect ribosomal protein genes. This report describes the…”
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Storage and secretion of Ag-Aper14, a novel peritrophic matrix protein, and Ag-Muc1 from the mosquito Anopheles gambiae by Devenport, M, Fujioka, H, Donnelly-Doman, M, Shen, Z, Jacobs-Lorena, M

“…The gene Ag-Aper14 encodes a novel peritrophic matrix (or peritrophic membrane; PM) protein in the mosquito Anopheles gambiae. The Ag-Aper14 protein is merely…”
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Pantropic retroviral vectors mediate somatic cell transformation and expression of foreign genes in dipteran insects by Jordan, T. V., Shike, H., Boulo, V., Cedeno, V., Fang, Q., Davis, B. S., Jacobs‐Lorena, M., Higgs, S., Fryxell1, K. J., Burns, J. C.

“…The control of insects that transmit disease and damage crops has become increasingly difficult. The ability to genetically engineer insects would facilitate…”
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Gene expression in Plasmodium: from gametocytes to sporozoites by Moreira, C.K., Marrelli, M.T., Jacobs-Lorena, M.

“…Completion of the complex developmental program of Plasmodium in the mosquito is essential for parasite transmission, yet this part of its life cycle is still…”
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Selective translational regulation of ribosomal protein gene expression during early development of Drosophila melanogaster by M A Kay, M Jacobs-Lorena

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The Journey of the Malaria Parasite in the Mosquito: Hopes for the New Century by Ghosh, A, Edwards, M.J, Jacobs-Lorena, M

“…In this review, Anil Ghosh, Marten Edwards and Marcelo Jacobs-Lorena follow the journey of the Plasmodium parasite in the mosquito vector. At each…”
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Plasmodium–mosquito interactions, phage display libraries and transgenic mosquitoes impaired for malaria transmission by Ghosh, A.K, Moreira, L.A, Jacobs-Lorena, M

“…Malaria continues to kill millions of people every year and new strategies to combat this disease are urgently needed. Recent advances in the study of the…”
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