Search Results - "Jacobs, Sharoni"
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SARS-CoV-2 variant Delta rapidly displaced variant Alpha in the United States and led to higher viral loads
Published in Cell reports. Medicine (15-03-2022)“…We report on the sequencing of 74,348 SARS-CoV-2 positive samples collected across the United States and show that the Delta variant, first detected in the…”
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High-Resolution Single Nucleotide Polymorphism Array Analysis of Epithelial Ovarian Cancer Reveals Numerous Microdeletions and Amplifications
Published in Clinical cancer research (15-08-2007)“…Purpose: Genetic changes in sporadic ovarian cancer are relatively poorly characterized compared with other tumor types. We have evaluated the use of…”
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Retinoic Acid Is Required Early during Adult Neurogenesis in the Dentate Gyrus
Published in Proceedings of the National Academy of Sciences - PNAS (07-03-2006)“…Retinoic acid (RA) is commonly used in vitro to differentiate stem cell populations including adult neural stem cells into neurons; however, the in vivo…”
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Genome-wide, high-resolution detection of copy number, loss of heterozygosity, and genotypes from formalin-fixed, paraffin-embedded tumor tissue using microarrays
Published in Cancer research (Chicago, Ill.) (15-03-2007)“…Formalin-fixed, paraffin-embedded (FFPE) material tends to yield degraded DNA and is thus suboptimal for use in many downstream applications. We describe an…”
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A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array
Published in BMC bioinformatics (03-05-2007)“…DNA copy number aberration (CNA) is one of the key characteristics of cancer cells. Recent studies demonstrated the feasibility of utilizing high density…”
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Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States
Published in Cell (13-05-2021)“…The highly transmissible B.1.1.7 variant of SARS-CoV-2, first identified in the United Kingdom, has gained a foothold across the world. Using S gene target…”
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Sample processing considerations for detecting copy number changes in formalin-fixed, paraffin-embedded tissues
Published in Cold Spring Harbor protocols (01-11-2012)“…The Whole Genome Sampling Analysis (WGSA) assay in combination with Affymetrix GeneChip Mapping Arrays is used for copy number analysis of high-quality DNA…”
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eP335: Genetic testing for APOB, LDLR, PCSK9, and LDLRAP1 suggest that FH testing may be underutilized
Published in Genetics in medicine (01-03-2022)Get full text
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Data analysis considerations for detecting copy number changes in formalin-fixed, paraffin-embedded tissues
Published in Cold Spring Harbor protocols (01-11-2012)“…The Whole Genome Sampling Analysis (WGSA) assay in combination with Affymetrix GeneChip Mapping Arrays is used for copy number analysis of high-quality DNA…”
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eP412 - Genetic screening of a reportedly healthy population for familial hypercholesterolemia
Published in Molecular genetics and metabolism (01-04-2021)Get full text
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Genetic screening of a reportedly healthy population for familial hypercholesterolemia
Published in Molecular genetics and metabolism (01-04-2021)Get full text
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Evidence for SARS-CoV-2 Delta and Omicron co-infections and recombination
Published in Med (New York, N.Y. : Online) (09-12-2022)“…Between November 2021 and February 2022, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants co-circulated in the United…”
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Abstract C10: Complete genome sequencing of complex tumors and matched normals results in sensitive detection of somatic events
Published in Cancer research (Chicago, Ill.) (15-09-2011)“…Abstract For a comprehensive understanding of the tumor genome, it is important to identify all somatic event types: point mutations, small insertions and…”
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Abstract 4955: Advances in gene expression microarray profiling from small amounts of adenocarcinoma and normal total RNA samples
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Gene expression profiling by microarray analysis provides an important avenue for understanding biological mechanisms, classifying tissue and tumor…”
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