Search Results - "Jacobs, L"

The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease by van der Veen, Jelske N., Kennelly, John P., Wan, Sereana, Vance, Jean E., Vance, Dennis E., Jacobs, René L.

“…Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy…”
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Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults by Buckley, Rachel F, Mormino, Elizabeth C, Rabin, Jennifer S, Hohman, Timothy J, Landau, Susan, Hanseeuw, Bernard J, Jacobs, Heidi I L, Papp, Kathryn V, Amariglio, Rebecca E, Properzi, Michael J, Schultz, Aaron P, Kirn, Dylan, Scott, Matthew R, Hedden, Trey, Farrell, Michelle, Price, Julie, Chhatwal, Jasmeer, Rentz, Dorene M, Villemagne, Victor L, Johnson, Keith A, Sperling, Reisa A

“…Mounting evidence suggests that sex differences exist in the pathologic trajectory of Alzheimer disease. Previous literature shows elevated levels of…”
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Mechanisms of MAVS Regulation at the Mitochondrial Membrane by Jacobs, Jana L., Coyne, Carolyn B.

“…Mitochondria have emerged as critical platforms for antiviral innate immune signaling. This is due in large part to the mitochondrial localization of the…”
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The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements by Gronenschild, Ed H B M, Habets, Petra, Jacobs, Heidi I L, Mengelers, Ron, Rozendaal, Nico, van Os, Jim, Marcelis, Machteld

“…FreeSurfer is a popular software package to measure cortical thickness and volume of neuroanatomical structures. However, little if any is known about…”
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Anomalous aortic origin of a coronary artery: The gaps and the guidelines by Jacobs, Marshall L., MD

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Self-discrepancies in mind perception for actual, ideal, and ought selves and partners by Jacobs, Oliver L, Pazhoohi, Farid, Kingstone, Alan

“…Defining and measuring self-discrepancies in mind perception between how an individual sees their actual self in comparison to their ideal or ought self has a…”
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A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans by Walker, Amy K., Jacobs, René L., Watts, Jennifer L., Rottiers, Veerle, Jiang, Karen, Finnegan, Deirdre M., Shioda, Toshi, Hansen, Malene, Yang, Fajun, Niebergall, Lorissa J., Vance, Dennis E., Tzoneva, Monika, Hart, Anne C., Näär, Anders M.

“…Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the synthesis and trafficking of cholesterol and other lipids and are critical…”
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Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals by Jacobs, Heidi I. L., Hedden, Trey, Schultz, Aaron P., Sepulcre, Jorge, Perea, Rodrigo D., Amariglio, Rebecca E., Papp, Kathryn V., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A.

“…Animal models of Alzheimer’s disease have suggested that tau pathology propagation, facilitated by amyloid pathology, may occur along connected pathways. To…”
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Novel insights on interactions between folate and lipid metabolism by da Silva, Robin P., Kelly, Karen B., Al Rajabi, Ala, Jacobs, René L.

“…Folate is an essential B vitamin required for the maintenance of AdoMet‐dependent methylation. The liver is responsible for many methylation reactions that are…”
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Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity by KOONEN, Debby P. Y, JACOBS, René L, FEBBRAIO, Maria, YOUNG, Martin E, SOLTYS, Carrie-Lynn M, ONG, Huy, VANCE, Dennis E, DYCK, Jason R. B

“…Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity Debby P.Y. Koonen 1 , René L. Jacobs 2 , Maria Febbraio 3 ,…”
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A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling by Van Der Veen, Jelske N., Lingrell, Susanne, McCloskey, Nicholas, Leblond, Nicholas D., Galleguillos, Danny, Zhao, Yuan Y., Curtis, Jonathan M., Sipione, Simonetta, Fullerton, Morgan D., Vance, Dennis E., René, Jacobs L.

“…ABSTRACTPhosphatidylethanolamine N‐methyltransferase (PEMT) is an important enzyme in hepatic phosphatidylcholine (PC) biosynthesis. Pemt−/− mice fed a…”
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Neurogenetic contributions to amyloid beta and tau spreading in the human cortex by Sepulcre, Jorge, Grothe, Michel J., d’Oleire Uquillas, Federico, Ortiz-Terán, Laura, Diez, Ibai, Yang, Hyun-Sik, Jacobs, Heidi I. L., Hanseeuw, Bernard J., Li, Quanzheng, El-Fakhri, Georges, Sperling, Reisa A., Johnson, Keith A.

“…Tau and amyloid beta (Aβ) proteins accumulate along neuronal circuits in Alzheimer’s disease. Unraveling the genetic background for the regional vulnerability…”
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Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting by Bajar, Bryce T., Wang, Emily S., Lam, Amy J., Kim, Bongjae B., Jacobs, Conor L., Howe, Elizabeth S., Davidson, Michael W., Lin, Michael Z., Chu, Jun

“…Many genetically encoded biosensors use Förster resonance energy transfer (FRET) to dynamically report biomolecular activities. While pairs of cyan and yellow…”
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Dietary Choline or Trimethylamine N-oxide Supplementation Does Not Influence Atherosclerosis Development in Ldlr-/- and Apoe-/- Male Mice by Aldana-Hernández, Paulina, Leonard, Kelly-Ann, Zhao, Yuan-Yuan, Curtis, Jonathan M, Field, Catherine J, Jacobs, René L

“…Choline, an essential nutrient, is required for cell membranes, lipoprotein secretion, and methyl-group metabolism. Recently, it has been proposed that excess…”
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Cost of New Technologies in Prostate Cancer Treatment: Systematic Review of Costs and Cost Effectiveness of Robotic-assisted Laparoscopic Prostatectomy, Intensity-modulated Radiotherapy, and Proton Beam Therapy by Schroeck, Florian Rudolf, Jacobs, Bruce L, Bhayani, Sam B, Nguyen, Paul L, Penson, David, Hu, Jim

“…Abstract Context Some of the high costs of robot-assisted radical prostatectomy (RARP), intensity-modulated radiotherapy (IMRT), and proton beam therapy may be…”
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Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3 by Koehler, Heather, Cotsmire, Samantha, Langland, Jeffrey, Kibler, Karen V., Kalman, Daniel, Uptone, Jason W., Mocarski, Edward S., Jacobs, Bertram L.

“…Vaccinia virus (VACV) encodes an innate immune evasion protein, E3, which contains an N-terminal Z-nucleic acid binding (Zα) domain that is critical for…”
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Bladder Cancer in 2010: How Far have We Come? by Jacobs, Bruce L., Lee, Cheryl T., Montie, James E.

“…Bladder cancer is the fourth most common cancer and ranks eighth as a cause of death from cancer among men in the United States. Although guidelines assist in…”
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A new ophthalmosaurid ichthyosaur from the Upper Jurassic (Early Tithonian) Kimmeridge Clay of Dorset, UK, with implications for Late Jurassic ichthyosaur diversity by Jacobs, Megan L, Martill, David M

“…A new ophthalmosaurid ichthyosaur, Thalassodraco etchesi gen. et sp. nov., from the Upper Jurassic Kimmeridge Clay Formation of Dorset, UK is described. The…”
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The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy by You, Jae-Sung, Mcnally, Rachel M., Jacobs, Brittany L., Privett, Rachel E., Gundermann, David M., Lin, Kuan-Hung, Steinert, Nate D., Goodman, Craig A., Hornberger, Troy A.

“…ABSTRACT It is well known that an increase in mechanical loading can induce skeletal muscle hypertrophy, and a long standing model in the field indicates that…”
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ZODIACAL EXOPLANETS IN TIME (ZEIT). I. A NEPTUNE-SIZED PLANET ORBITING AN M4.5 DWARF IN THE HYADES STAR CLUSTER by Mann, Andrew W., Gaidos, Eric, Mace, Gregory N., Johnson, Marshall C., Bowler, Brendan P., LaCourse, Daryll, Jacobs, Thomas L., Vanderburg, Andrew, Kraus, Adam L., Kaplan, Kyle F., Jaffe, Daniel T.

“…ABSTRACT Studying the properties of young planetary systems can shed light on how the dynamics and structure of planets evolve during their most formative…”
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