Search Results - "Jacobs, Julie S"

TRPA channels distinguish gravity sensing from hearing in Johnston's organ by Sun, Yishan, Liu, Lei, Ben-Shahar, Yehuda, Jacobs, Julie S, Eberl, Daniel F, Welsh, Michael J

“…Although many animal species sense gravity for spatial orientation, the molecular bases remain uncertain. Therefore, we studied Drosophila melanogaster, which…”
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The retrograde IFT dynein is required for normal function of diverse mechanosensory cilia in Drosophila by Sharma, Yashoda, Jacobs, Julie S., Sivan-Loukianova, Elena, Lee, Eugene, Kernan, Maurice J., Eberl, Daniel F.

“…Cilia biogenesis relies on intraflagellar transport (IFT), a conserved transport mechanism which functions bi-directionally to bring protein complexes to the…”
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Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing by Karak, Somdatta, Jacobs, Julie S., Kittelmann, Maike, Spalthoff, Christian, Katana, Radoslaw, Sivan-Loukianova, Elena, Schon, Michael A., Kernan, Maurice J., Eberl, Daniel F., Göpfert, Martin C.

“…Much like vertebrate hair cells, the chordotonal sensory neurons that mediate hearing in Drosophila are motile and amplify the mechanical input of the ear…”
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Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development by Todi, Sokol V, Sivan-Loukianova, Elena, Jacobs, Julie S, Kiehart, Daniel P, Eberl, Daniel F

“…Myosin VIIA (MyoVIIA) is an unconventional myosin necessary for vertebrate audition [1]-[5]. Human auditory transduction occurs in sensory hair cells with a…”
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Role of miR-204 in segmental cardiac effects of phenylephrine and pressure overload by Gaddam, Ravinder Reddy, Amalkar, Veda Sudhir, Sali, Veeresh Kumar, Nakuluri, Krishnamurthy, Jacobs, Julie S., Kim, Young-Rae, Li, Quixia, Bahal, Raman, Irani, Kaikobad, Vikram, Ajit

“…Cardiotoxicity caused by adrenergic receptor agonists overdosing or stress-induced catecholamine release promotes cardiomyopathy, resembling Takotsubo…”
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Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion by Guo, Yanmeng, Wang, Yuping, Zhang, Wei, Meltzer, Shan, Zanini, Damiano, Yu, Yue, Li, Jiefu, Cheng, Tong, Guo, Zhenhao, Wang, Qingxiu, Jacobs, Julie S., Sharma, Yashoda, Eberl, Daniel F., Göpfert, Martin C., Jan, Lily Yeh, Jan, Yuh Nung, Wang, Zuoren

“…Drosophila larval locomotion, which entails rhythmic body contractions, is controlled by sensory feedback from proprioceptors. The molecular mechanisms…”
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A "mesmer"izing new approach to site-directed mutagenesis in large transformation-ready constructs: Mutagenesis via Serial Small Mismatch Recombineering by Jacobs, Julie S., Hong, Xiaojing, Eberl, Daniel F.

“…Creating designer mutations in large genes is a challenge. Size limitations imposed by site-directed mutagenesis (SDM), coupled with the paucity of unique…”
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Methylthioadenosine phosphorylase (MTAP) in hearing: Gene disruption by chromosomal rearrangement in a hearing impaired individual and model organism analysis by Williamson, Robin E., Darrow, Keith N., Michaud, Sebastien, Jacobs, Julie S., Jones, Marilyn C., Eberl, Daniel F., Maas, Richard L., Liberman, M. Charles, Morton, Cynthia C.

“…Genes with a role in the auditory system have been mapped by genetic linkage analysis of families with heritable deafness and then cloned through positional…”
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Neg, a nerve growth factor-stimulated gene expressed by fetal neocortical neurons that is downregulated by ethanol by Miller, Michael W., Jacobs, Julie S., Yokoyama, Ruth

“…Neurotrophins are critical for neuronal development, plasticity, and survival. Ethanol affects these processes. We tested the hypothesis that ethanol inhibits…”
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Cell cycle kinetics and immunohistochemical characterization of dissociated fetal neocortical cultures: evidence that differentiated neurons have mitotic capacity by Jacobs, Julie S, Miller, Michael W

“…Neurons in the neocortex (regardless of their developmental state) are considered to be post-mitotic and incapable of dividing. We used dissociated primary…”
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A “mesmer”izing new approach to site-directed mutagenesis in large transformation-ready constructs: utagenesis via by Jacobs, Julie S, Hong, Xiaojing, Eberl, Daniel F

“…Creating designer mutations in large genes is a challenge. Size limitations imposed by site-directed mutagenesis (SDM) coupled with the paucity of unique…”
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Methylthioadenosine phosphorylase (MTAP) in hearing : Gene disruption by chromosomal rearrangement in a hearing impaired individual and model organism analysis: Special issue: The genetic basis of deafness by WILLIAMSON, Robin E, DARROW, Keith N, MICHAUD, Sebastien, JACOBS, Julie S, JONES, Marilyn C, EBERL, Daniel F, MAAS, Richard L, LIBERMAN, Charles, MORTON, Cynthia C

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Proliferation and death of cultured fetal neocortical neurons: Effects of ethanol on the dynamics of cell growth by Jacobs, Julie S, Miller, Michael W

“…Neuronal number in the mature CNS is determined by the balance of cell proliferation and death. The effects of ethanol on cell proliferation and death were…”
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Expression of nerve growth factor, p75, and the high affinity neurotrophin receptors in the adult rat trigeminal system: Evidence for multiple trophic support systems by Jacobs, Julie S, Miller, Michael W

“…We hypothesize that discrete trigeminal structures have the components required for autocrine regulation as well as redundant neurotrophin support systems. We…”
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Expression of nerve growth factor, p75, and the high affinity neurotrophin receptors in the adult rat trigeminal system: evidence for multiple trophic support systems by Jacobs, J S, Miller, M W

“…We hypothesize that discrete trigeminal structures have the components required for autocrine regulation as well as redundant neurotrophin support systems. We…”
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