Search Results - "Jacobs, Heidi IL"

Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults by Scott, Matthew R., Hampton, Olivia L., Buckley, Rachel F., Chhatwal, Jasmeer P., Hanseeuw, Bernard J., Jacobs, Heidi IL, Properzi, Michael J., Sanchez, Justin S., Johnson, Keith A., Sperling, Reisa A., Schultz, Aaron P.

“…Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom…”
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Dynamic behavior of the locus coeruleus during arousal-related memory processing in a multi-modal 7T fMRI paradigm by Jacobs, Heidi Il, Priovoulos, Nikos, Poser, Benedikt A, Pagen, Linda Hg, Ivanov, Dimo, Verhey, Frans Rj, Uludağ, Kâmil

“…A body of animal and human evidence points to the norepinephrine (NE) locus coeruleus (LC) system in modulating memory for arousing experiences, but whether…”
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Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions by Veréb, Dániel, Mijalkov, Mite, Canal-Garcia, Anna, Chang, Yu-Wei, Gomez-Ruiz, Emiliano, Gerboles, Blanca Zufiria, Kivipelto, Miia, Svenningsson, Per, Zetterberg, Henrik, Volpe, Giovanni, Betts, Matthew, Jacobs, Heidi IL, Pereira, Joana B

“…The locus coeruleus (LC) is an important noradrenergic nucleus that has recently attracted a lot of attention because of its emerging role in cognitive and…”
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Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults by Biddle, Kelsey D., d'Oleire Uquillas, Federico, Jacobs, Heidi I.L., Zide, Benjamin, Kirn, Dylan R., Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Donovan, Nancy J.

“…•What is the primary question addressed by this study? Do cognitive decline and social disengagement co-occur in cognitively normal older adults and are these…”
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Meta-analysis of functional network alterations in Alzheimer's disease: Toward a network biomarker by JACOBS, Heidi I. L, RADUA, Joaquim, LÜCKMANN, Helen C, SACK, Alexander T

“…The increasing prevalence of Alzheimer's disease (AD) emphasizes the need for sensitive biomarkers. Memory, a core deficit in AD, involves the interaction of…”
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The cross-functional role of frontoparietal regions in cognition: internal attention as the overarching mechanism by Lückmann, Helen C, Jacobs, Heidi I L, Sack, Alexander T

“…Neuroimaging studies have repeatedly reported findings of activation in frontoparietal regions that largely overlap across various cognitive functions. Part of…”
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Parietal cortex matters in Alzheimer's disease: An overview of structural, functional and metabolic findings by JACOBS, Heidi I. L, VAN BOXTEL, Martin P. J, JOLLES, Jelle, VERHEY, Frans RJ, UYLINGS, Harry B. M

“…Atrophy of the medial temporal lobe, especially the hippocampus and the parahippocampal gyrus, is considered to be the most predictive structural brain…”
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Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions by Veréb, Dániel, Mijalkov, Mite, Canal-Garcia, Anna, Chang, Yu-Wei, Gomez-Ruiz, Emiliano, Gerboles, Blanca Zufiria, Kivipelto, Miia, Svenningsson, Per, Zetterberg, Henrik, Volpe, Giovanni, Betts, Matthew, Jacobs, Heidi IL, Pereira, Joana B

“…The locus coeruleus (LC) is an important noradrenergic nucleus that has recently attracted a lot of attention because of its emerging role in cognitive and…”
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Contribution of extracerebral tracer retention and partial volume effects to sex differences in Flortaucipir-PET signal by Scott, Matthew R, Edwards, Natalie C, Properzi, Michael J, Jacobs, Heidi IL, Price, Julie C, Lois, Cristina, Farrell, Michelle E, Hanseeuw, Bernard J, Thibault, Emma G, Rentz, Dorene M, Johnson, Keith A, Sperling, Reisa A, Schultz, Aaron P, Buckley, Rachel F

“…Clinically normal females exhibit higher 18F-flortaucipir (FTP)-PET signal than males across the cortex. However, these sex differences may be explained by…”
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Alzheimer's disease: the downside of a highly evolved parietal lobe? by Bruner, Emiliano, Jacobs, Heidi I L

“…Clinical grade Alzheimer's disease (AD) is only described in humans. Recent imaging studies in early AD patients showed that the parietal areas display the…”
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Relevance of parahippocampal-locus coeruleus connectivity to memory in early dementia by Jacobs, Heidi I.L, Wiese, Svenja, van de Ven, Vincent, Gronenschild, Ed H.B.M, Verhey, Frans R.J, Matthews, Paul M

“…Abstract Neuropathology suggests an important role for the locus coeruleus (LC) in Alzheimer's disease (AD) pathophysiology. Neuropathology and structural…”
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P3‐414: LOCUS COERULEUS HYPERMETABOLISM IS ASSOCIATED WITH AMYLOID‐RELATED MEDIAL TEMPORAL TAU PATHOLOGY by Jacobs, Heidi IL, Dutta, Joyita, Becker, Alex, Hanseeuw, Bernard J., Sepulcre, Jorge, Sperling, Reisa A., Johnson, Keith A.

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LOCUS COERULEUS HYPERMETABOLISM IS ASSOCIATED WITH AMYLOID-RELATED MEDIAL TEMPORAL TAU PATHOLOGY by Jacobs, Heidi IL, Dutta, Joyita, Becker, Alex, Hanseeuw, Bernard J., Sepulcre, Jorge, Sperling, Reisa A., Johnson, Keith A.

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LOWER BASELINE MEMORY PERFORMANCE IS ASSOCIATED WITH INCREASES IN WORRIES ABOUT COGNITIVE PERFORMANCE IN APOE E4 CARRIERS by Pagen, Linda H.G., Verhey, Frans R.J., van Boxtel, Martin P.J., Poser, Benedikt A., Goebel, Rainer, Jacobs, Heidi IL

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P1‐480: LOCUS COERULEUS SIGNAL INTENSITY IS ASSOCIATED WITH ENTORHINAL TAU PATHOLOGY AT HIGHER LEVELS OF AMYLOID BURDEN by Jacobs, Heidi IL, Becker, Alex, Kwong, Kenneth, Uquillas, Federico d'Oleire, Sperling, Reisa A., Johnson, Keith A.

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LOCUS COERULEUS SIGNAL INTENSITY IS ASSOCIATED WITH ENTORHINAL TAU PATHOLOGY AT HIGHER LEVELS OF AMYLOID BURDEN by Jacobs, Heidi IL, Becker, Alex, Kwong, Kenneth, Uquillas, Federico d’Oleire, Sperling, Reisa A., Johnson, Keith A.

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O1‐10‐03: ANATOMICAL STAGING OF BETA‐AMYLOID ACCUMULATION BASED ON LONGITUDINAL ASSESSMENT OF GLOBALLY PIB NEGATIVE ADULTS by Farrell, Michelle E., Schultz, Aaron P., Properzi, Michael J., Jacobs, Heidi IL, Hanseeuw, Bernard J., Buckley, Rachel F., Sperling, Reisa A., Johnson, Keith A.

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P3‐305: SYNERGISTIC ADVERSE EFFECTS OF WIDOWHOOD AND AMYLOID‐β ON COGNITIVE DECLINE IN COGNITIVELY NORMAL OLDER ADULTS by Biddle, Kelsey D., Uquillas, Federico d'Oleire, Zide, Benjamin, Kirn, Dylan, Jacobs, Heidi IL, Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Donovan, Nancy J.

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IC‐P‐008: ANATOMICAL STAGING OF BETA‐AMYLOID ACCUMULATION BASED ON LONGITUDINAL ASSESSMENT OF GLOBALLY PIB NEGATIVE ADULTS by Farrell, Michelle E., Schultz, Aaron P., Properzi, Michael J., Jacobs, Heidi IL, Hanseeuw, Bernard J., Buckley, Rachel F., Sperling, Reisa A., Johnson, Keith A.

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SYNERGISTIC ADVERSE EFFECTS OF WIDOWHOOD AND AMYLOID-β ON COGNITIVE DECLINE IN COGNITIVELY NORMAL OLDER ADULTS by Biddle, Kelsey D., Uquillas, Federico d’Oleire, Zide, Benjamin, Kirn, Dylan, Jacobs, Heidi IL, Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Donovan, Nancy J.

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