Search Results - "Jacobs, Erica Y"
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1
Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization
Published in Genes & development (15-01-2012)“…Protein lysine methylation is one of the most widespread post-translational modifications in the nuclei of eukaryotic cells. Methylated lysines on histones and…”
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2
Integrative structure and functional anatomy of a nuclear pore complex
Published in Nature (London) (22-03-2018)“…Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and…”
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Residual Cajal Bodies in Coilin Knockout Mice Fail to Recruit Sm snRNPs and SMN, the Spinal Muscular Atrophy Gene Product
Published in The Journal of cell biology (23-07-2001)“…Cajal bodies (CBs) are nuclear suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs). In addition to snRNPs, they are highly…”
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4
A new generation of nanobody research tools using improved mass spectrometry-based discovery methods
Published in The Journal of biological chemistry (01-09-2024)“…Single-domain antibodies (“nanobodies”) derived from the variable region of camelid heavy-chain only antibody variants have proven to be widely useful tools…”
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Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease
Published in The Journal of biological chemistry (01-06-2022)“…Picornaviruses are small RNA viruses that hijack host cell machinery to promote their replication. During infection, these viruses express two proteases, 2Apro…”
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Role of the C-Terminal Domain of RNA Polymerase II in U2 snRNA Transcription and 3′ Processing
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
Published in eLife (15-12-2021)“…The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral…”
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8
HIV–host interactome revealed directly from infected cells
Published in Nature microbiology (01-07-2016)“…Although genetically compact, HIV-1 commandeers vast arrays of cellular machinery to sustain and protect it during cycles of viral outgrowth…”
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Coiled bodies preferentially associate with U4, U11, and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes
Published in Molecular biology of the cell (01-05-1999)“…Coiled bodies (CBs) are nuclear organelles involved in the metabolism of small nuclear RNAs (snRNAs) and histone messages. Their structural morphology and…”
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