Search Results - "Jacobs, Erica"
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Integrative structure and functional anatomy of a nuclear pore complex
Published in Nature (London) (22-03-2018)“…Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and…”
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Ginkgo Biloba Extract in Ophthalmic and Systemic Disease, With a Focus on Normal-Tension Glaucoma
Published in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) (01-05-2020)“…Glaucoma is a neurodegenerative eye disease that results in retinal ganglion cell loss and ultimately loss of vision. Elevated intraocular pressure (IOP) is…”
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A new generation of nanobody research tools using improved mass spectrometry-based discovery methods
Published in The Journal of biological chemistry (01-09-2024)“…Single-domain antibodies (“nanobodies”) derived from the variable region of camelid heavy-chain only antibody variants have proven to be widely useful tools…”
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Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization
Published in Genes & development (15-01-2012)“…Protein lysine methylation is one of the most widespread post-translational modifications in the nuclei of eukaryotic cells. Methylated lysines on histones and…”
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Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease
Published in The Journal of biological chemistry (01-06-2022)“…Picornaviruses are small RNA viruses that hijack host cell machinery to promote their replication. During infection, these viruses express two proteases, 2Apro…”
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Mapping outcomes for recovery of consciousness in studies from 1986 to 2020: a scoping review protocol
Published in BMJ open (01-06-2022)“…IntroductionHistorically, heterogeneous outcome assessments have been used to measure recovery of consciousness in patients with disorders of consciousness…”
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HIV–host interactome revealed directly from infected cells
Published in Nature microbiology (01-07-2016)“…Although genetically compact, HIV-1 commandeers vast arrays of cellular machinery to sustain and protect it during cycles of viral outgrowth…”
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Feasibility of the Transport PLUS intervention to improve the transitions of care for patients transported home by ambulance: a non-randomized pilot study
Published in Pilot and feasibility studies (05-08-2022)“…Background The growing population of patients over the age of 65 faces particular vulnerability following discharge after hospitalization or an emergency room…”
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Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
Published in eLife (15-12-2021)“…The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral…”
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Residual Cajal Bodies in Coilin Knockout Mice Fail to Recruit Sm snRNPs and SMN, the Spinal Muscular Atrophy Gene Product
Published in The Journal of cell biology (23-07-2001)“…Cajal bodies (CBs) are nuclear suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs). In addition to snRNPs, they are highly…”
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Role of the C-Terminal Domain of RNA Polymerase II in U2 snRNA Transcription and 3′ Processing
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Clinical spectrum of orbital and ocular abnormalities on fetal MRI
Published in Pediatric radiology (2023)“…Background Fetal magnetic resonance imaging (MRI) may reveal sonographically occult ocular abnormalities. When discovered, acquired causes and genetic…”
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Coiled bodies preferentially associate with U4, U11, and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes
Published in Molecular biology of the cell (01-05-1999)“…Coiled bodies (CBs) are nuclear organelles involved in the metabolism of small nuclear RNAs (snRNAs) and histone messages. Their structural morphology and…”
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Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants
Published in The Journal of cell biology (01-08-1994)“…To understand the mechanisms of mRNA transport in eukaryotes, we have isolated Saccharomyces cerevisiae temperature-sensitive (ts) mutants which accumulate…”
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