Search Results - "Jacobelli, J."
-
1
Immune cell trafficking to the islets during type 1 diabetes
Published in Clinical and experimental immunology (01-12-2019)“…Summary Inhibition of immune cell trafficking to the pancreatic islets during type 1 diabetes (T1D) has therapeutic potential, since targeting of T cell and B…”
Get full text
Journal Article -
2
Cutting Edge: Functional Role for Proline-Rich Tyrosine Kinase 2 in NK Cell-Mediated Natural Cytotoxicity
Published in The Journal of immunology (1950) (01-03-2000)“…Protein tyrosine kinase activation is one of the first biochemical events in the signaling pathway leading to activation of NK cell cytolytic machinery. Here…”
Get full text
Journal Article -
3
Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder
Published in British journal of cancer (01-02-1999)“…Transitional cell carcinoma of the bladder is one of the human cancers most responsive to immunotherapy, and local interleukin-2 (IL-2) production appears to…”
Get full text
Journal Article -
4
Integrin-mediated regulation of cytokine and chemokine production by human natural killer cells
Published in European cytokine network (Montrouge) (01-09-2000)Get more information
Journal Article -
5
A single class II myosin modulates T cell motility and stopping, but not synapse formation
Published in Nature immunology (01-05-2004)“…Upon encountering an antigen, motile T cells stop crawling, change morphology and ultimately form an 'immunological synapse'. Although myosin motors are…”
Get full text
Journal Article -
6
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect
Published in Blood (15-07-2004)“…In this study we show that Wiskott-Aldrich syndrome protein (WASp), a critical regulator of actin cytoskeleton that belongs to the Scar/WAVE family, plays a…”
Get full text
Journal Article -
7
RAC1/P38 MAPK Signaling Pathway Controls beta 1 Integrin-Induced Interleukin-8 Production in Human Natural Killer Cells
Published in Immunity (Cambridge, Mass.) (01-01-2000)“…The MAP kinase (MAPK) p38 plays a key role in regulating inflammatory responses. Here, we demonstrate that beta 1 integrin ligation on human NK cells results…”
Get full text
Journal Article -
8
New views of the immunological synapse: variations in assembly and function
Published in Current opinion in immunology (01-06-2004)“…The interaction of T cells with antigen-presenting cells results in the formation of a contact face, termed the immunological synapse. The prototypical…”
Get full text
Journal Article -
9
Proline-Rich Tyrosine Kinase 2 and Rac Activation by Chemokine and Integrin Receptors Controls NK Cell Transendothelial Migration
Published in The Journal of immunology (1950) (15-03-2003)“…Protein tyrosine kinase activation is an important requisite for leukocyte migration. Herein we demonstrate that NK cell binding to endothelium activates…”
Get full text
Journal Article -
10
Mechanisms of T cell motility and arrest: Deciphering the relationship between intra- and extracellular determinants
Published in Seminars in Immunology (01-12-2005)“…T lymphocytes are capable of rapid motility in vitro and in vivo. Upon antigen recognition, they may stop crawling and form a stable cell–cell contact called…”
Get full text
Journal Article -
11
Integrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells
Published in The Journal of experimental medicine (05-10-1998)“…Recent evidence indicates that integrin engagement results in the activation of biochemical signaling events important for regulating different cell functions,…”
Get full text
Journal Article -
12
T cell synapse assembly: proteins, motors and the underlying cell biology
Published in Seminars in immunology (01-02-2005)“…A tantalizing feature of the ‘immunological synapse’ is the segregation of transmembrane proteins into activating clusters and their underlying signalosomes…”
Get full text
Journal Article -
13
Candida albicans Expresses a Focal Adhesion Kinase-Like Protein That Undergoes Increased Tyrosine Phosphorylation upon Yeast Cell Adhesion to Vitronectin and the EA.hy 926 Human Endothelial Cell Line
Published in Infection and Immunity (01-07-2002)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
14
Functional Role for Proline-Rich Tyrosine Kinase 2 in NK Cell-Mediated Natural Cytotoxicity
Published in The Journal of immunology (1950) (01-03-2000)“…Protein tyrosine kinase activation is one of the first biochemical events in the signaling pathway leading to activation of NK cell cytolytic machinery. Here…”
Get full text
Journal Article -
15
RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells
Published in Immunity (Cambridge, Mass.) (01-01-2000)“…The MAP kinase (MAPK) p38 plays a key role in regulating inflammatory responses. Here, we demonstrate that beta1 integrin ligation on human NK cells results in…”
Get full text
Journal Article -
16
Demographic emergency: too much? Too few? Or badly distributed?
Published in Genus (01-04-2004)Get full text
Book Review