Search Results - "Jacob, Noam"

Cytokine disturbances in systemic lupus erythematosus by Jacob, Noam, Stohl, William

“…The pathogenesis of systemic lupus erythematosus (SLE) is complex, and the resulting disease manifestations are heterogeneous. Cytokine dysregulation is…”
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Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease by Agrawal, Hemant, Jacob, Noam, Carreras, Esther, Bajana, Sandra, Putterman, Chaim, Turner, Sean, Neas, Barbara, Mathian, Alexis, Koss, Michael N, Stohl, William, Kovats, Susan, Jacob, Chaim O

“…Type I IFNs are potent regulators of innate and adaptive immunity and are implicated in the pathogenesis of systemic lupus erythematosus. Here we report that…”
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Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway by Jacob, Noam, Yang, Haitao, Pricop, Luminita, Liu, Yi, Gao, Xiaoni, Zheng, Song Guo, Wang, Juhua, Gao, Hua-Xin, Putterman, Chaim, Koss, Michael N, Stohl, William, Jacob, Chaim O

“…TNF-alpha has both proinflammatory and immunoregulatory functions. Whereas a protective role for TNF administration in systemic lupus erythematosus (SLE)-prone…”
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Genetics of Rheumatoid Arthritis: An Impressionist Perspective by Jacob, Noam, MD, Jacob, Chaim O., MD, PhD

“…Rheumatoid arthritis (RA) is the most common rheumatic disease. The genetic basis of RA is supported through the identification of more than 30 susceptibility…”
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Development of Systemic Lupus Erythematosus in NZM 2328 Mice in the Absence of any Single BAFF Receptor by Jacob, Chaim O., Yu, Ning, Guo, Shunhua, Jacob, Noam, Quinn, William J., Sindhava, Vishal, Cancro, Michael P., Goilav, Beatrice, Putterman, Chaim, Migone, Thi‐Sau, Stohl, William

“…Objective To determine the necessity for any individual BAFF receptor in the development of systemic lupus erythematosus (SLE). Methods Bcma‐, Taci‐, and…”
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Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome by Jacob, Noam, Jacobs, Jonathan P., Kumagai, Kotaro, Ha, Connie W.Y., Kanazawa, Yoshitake, Lagishetty, Venu, Altmayer, Katherine, Hamill, Ariel M., Von Arx, Aimee, Sartor, R. Balfour, Devkota, Suzanne, Braun, Jonathan, Michelsen, Kathrin S., Targan, Stephan R., Shih, David Q.

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Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD by Jacob, Noam, Targan, Stephan R, Shih, David Q

“…The frequency of fibrosing Crohn’s disease (CD) is significant, with approximately 40% of CD patients with ileal disease developing clinically apparent…”
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DOPPLER ENDOSCOPIC PROBE BLOOD FLOW MONITORING AND FOCAL TREATMENT PREVENT DELAYED POST-POLYPECTOMY INDUCED ULCER HEMORRHAGE IN A RANDOMIZED CONTROLLED TRIAL by Jensen, Dennis, Jutabha, Rome, Dulai, Gareth, Jacob, Noam, Gornbein, Jeffrey

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S767 Doppler Endoscopic Probe Blood Flow Monitoring and Focal Treatment Prevents Delayed Post-Polypectomy-Induced Ulcer Hemorrhage in a Randomized Controlled Trial by Jensen, Dennis, Jutabha, Rome, Dulai, Gareth, Jacob, Noam, Gornbein, Jeffrey

“…Patients were stratified by whether they took chronic anti-platelet or anti-thrombotic drugs & had a PPIU of 10-40 mm; or for those without bleed drugs, PPIU’s…”
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IMPROVEMENTS IN RISK STRATIFICATION AND COLONOSCOPIC HEMOSTASIS TO PREVENT DELAYED POST-POLYPECTOMY INDUCED ULCER HEMORRHAGE by Jensen, Dennis, Lewis, Michael, Jacob, Noam, Fejleh, M. Phillip, Wang, Hanlin

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STUDY METHODS AND INTERIM RESULTS OF RANDOMIZED CONTROLLED TRIAL (RCT) OF BLOOD FLOW MONITORING TO PREVENT DELAYED POST-POLYPECTOMY INDUCED ULCER HEMORRHAGE (DPPIUH) by Jensen, Dennis M., Jutabha, Rome, Dulai, Gareth, Jacob, Noam, Gornbein, Jeffrey

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Mo1253 MILLION VETERAN PROGRAM (MVP) GWAS AND TRANSCRIPTOMICS OF XENOGRAFTED COLORECTAL NEOPLASIA REVEALS A NEUROENDOCRINE PHENOTYPE MEDIATED BY BASOACTIVE INTESTINAL POLYPEPTIDE (VIP) by Ko, Arthur, Oh, Suwan, Jacobs, Jonathan P., Lewis, Michael, Kuc, Alma, Kosoyan, Hovsep P., Jacob, Noam, Germano, Patrizia M., Bouvet, Michael, Singh, Satish K., Pisegna, Joseph R.

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Sa1851 THE EFFECT OF DYSBIOTIC GUT MICROBIOTA IN FAMILIES WITH PEDIATRIC IBD ON INTESTINAL INFLAMMATION IN HUMANIZED GNOTOBIOTIC TL1A TRANSGENIC MICE by Koletic, Carolina F., Lagishetty, Venu, Zhou, Yi, Chandra, Franciscus, Arias-Jayo, Nerea, Chang, Candace, Yang, Julianne C., Liang, Fengting, Chaganti, Anil, Sedighian, Farzaneh, Targan, Stephan, Jacob, Noam, Xanthou, Georgina, Jacobs, Jonathan P.

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Accelerated Development of Glomerulonephritis in TNF Receptor 1 and 2 Double-knockout Lupus-mice by Jacob, Noam, Research Fellow, University of Southern California Keck School of Medicine, Los Angeles, CA, Pricop, Luminita, Associate Professor of Medicine, Hospital for Special Surgery, New York, NY, Chaim Putterman, Associate Professor, Albert Einstein College of Medicine/ Department of Medicine, Bronx, NY, Jacob, Chaim O., Associate Professor of Medicine, University of Southern California Keck School of Medicine/Department of Medicine, Los Angeles, CA, Koss, Michael, Professor of Pathology, University of Southern California Keck School of Medicine/Department of Pathology, Los Angeles, CA

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PATIENT AND PROCEDURAL FACTORS THAT IMPACT ON REAL TIME MAXIMUM INSERTION PAIN IN UNSEDATED WATER EXCHANGE COLONOSCOPY - A SINGLE (PATIENT) BLINDED MULTI-SITE, RANDOMIZED CONTROLLED TRIAL IN VETERANS by Leung, Felix, Chen, Yu, Cheung, Ramsey, Dixit, Vivek, Elashoff, David, Friedland, Shai, Jacob, Noam, Jamgotchian, Nora, Jia, Hui, Leung, Joseph, Pan, Jennifer, Quan, Susan, Saha, Angshuman, Shaikh, Aliya, Sul, James, Wilhalme, Holly, Yen, Andrew

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PATIENT AND PROCEDURAL FACTORS THAT IMPACT ON REAL TIME MAXIMUM INSERTION PAIN IN UNSEDATED WATER EXCHANGE COLONOSCOPY - A SINGLE (PATIENT) BLINDED MULTI-SITE, RANDOMIZED CONTROLLED TRIAL IN VETERANS by Leung, Felix, Chen, Yu, Cheung, Ramsey, Dixit, Vivek, Elashoff, David, Friedland, Shai, Jacob, Noam, Jamgotchian, Nora, Jia, Hui, Leung, Joseph, Pan, Jennifer, Quan, Susan, Saha, Angshuman, Shaikh, Aliya, Sul, James, Wilhalme, Holly, Yen, Andrew

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Mo1170 MICROBIOME BIOGEOGRAPHY ALONG THE GASTROINTESTINAL TRACT IS OBSERVED IN SPECIFIC PATHOGEN-FREE MICE AND IS PARTIALLY RECAPITULATED IN COLONIZED GERM-FREE MICE by Yang, Julianne C., Lagishetty, Venu, Arias-Jayo, Nerea, Chang, Candace, Hauer, Megan, Katzka, William, Zhou, Yi, Sedighian, Farzaneh, Koletic, Carolina, Liang, Fengting, Dong, Tien S., Situ, Jamilla, Troutman, Ryan, Buri, Heidi A., Simpson, Carra, Jacob, Noam, Jacobs, Jonathan P.

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Mo1791 THE EFFECT OF DYSBIOTIC GUT MICROBIOME OF FAMILIES WITH PEDIATRIC IBD ON INTESTINAL INFLAMMATION AND FIBROSIS IN HUMANIZED GNOTOBIOTIC TL1A TRANSGENIC MICE by Koletic, Carolina F., Lagishetty, Venu, Arias-Jayo, Nerea, Zhou, Yi, Chang, Candace, Yang, Julianne C., Liang, Fengting, Chaganti, Anil, Sedighian, Farzaneh, Jacob, Noam, Targan, Stephan, Xanthou, Georgina, Jacobs, Jonathan P.

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Prospective randomized controlled trial of water exchange plus cap versus water exchange colonoscopy in unsedated veterans by Leung, Felix W., Cheung, Ramsey, Friedland, Shai, Jacob, Naom, Leung, Joseph W., Pan, Jennifer Y., Quan, Susan Y., Sul, James, Yen, Andrew W., Jamgotchian, Nora, Chen, Yu, Dixit, Vivek, Shaikh, Aliya, Elashoff, David, Saha, Angshuman, Wilhalme, Holly

“…Water exchange (WE) and cap-assisted colonoscopy separately have been shown to reduce pain during insertion in unsedated patients. We hypothesized that…”
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Tu1484: MICROBIAL METABOLITE ACETATE DRIVES ILEAL INFLAMMATION IN GERM-FREE MICE by Jacob, Noam, Alexeev, Erica, Ye, Yuefang, Blackwood, Anna Y., Thomas, Lisa S., Miller, Jordan H., Stamps, Dalton T., Sedighian, Farzaneh, Hamade, Hussein, Jacobs, Jonathan P., Targan, Stephan R., Michelsen, Kathrin S.

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