Unusual clinical presentation of brucellosis caused by Brucella canis

1 Brucellosis Laboratory, Administración Nacional de Laboratorios e Institutos de Salud Dr C. G. Malbrán (ANLIS), Avda. Velez Sarsfield 563, 1281 Buenos Aires, Argentina 2 Unidad de Transplante Renal, Hospital Cosme Argerich, Margall 750, 1155 Buenos Aires, Argentina 3 Hospital Naval ‘Pedro Mallo�...

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Published in:Journal of medical microbiology Vol. 54; no. 5; pp. 505 - 508
Main Authors: Lucero, Nidia E, Jacob, Nestor O, Ayala, Sandra M, Escobar, Gabriela I, Tuccillo, Patricia, Jacques, Isabelle
Format: Journal Article
Language:English
Published: Reading Soc General Microbiol 01-05-2005
Society for General Microbiology
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Summary:1 Brucellosis Laboratory, Administración Nacional de Laboratorios e Institutos de Salud Dr C. G. Malbrán (ANLIS), Avda. Velez Sarsfield 563, 1281 Buenos Aires, Argentina 2 Unidad de Transplante Renal, Hospital Cosme Argerich, Margall 750, 1155 Buenos Aires, Argentina 3 Hospital Naval ‘Pedro Mallo', Patricias Argentinas 351, 1405 Buenos Aires, Argentina 4 Laboratoire de Pathologie Infectieuse et Immunologie, Institut National de la Recherche Agronomique, 37380 Nouzilly, France Correspondence Nidia E. Lucero nidia{at}elsitio.net Received October 13, 2004 Accepted January 13, 2005 Brucella canis is considered a rare cause of human brucellosis. The clinical importance of this infection may have been underestimated so far because of difficulties with presumptive diagnosis. The case described here presented symptoms compatible with brucellosis but the routine tests using Brucella abortus antigen were negative. The infection would have remained undiagnosed if culture had not been positive. This case illustrates the potential for a favourable outcome in Brucella canis diagnosis and supports recommendations for the use of B. canis serology. The infection should be suspected in patients with compatible symptoms and negative serology for B. abortus antigen. Abbreviations: CELISA, competitive ELISA; CMV, cytomegalovirus; IELISA, indirect ELISA; RSAT, rapid screening agglutination test.
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ISSN:0022-2615
1473-5644
DOI:10.1099/jmm.0.45928-0