Search Results - "Jacob, Megan"

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    Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections by Gilbertie, Jessica M, Schnabel, Lauren V, Hickok, Noreen J, Jacob, Megan E, Conlon, Brian P, Shapiro, Irving M, Parvizi, Javad, Schaer, Thomas P

    Published in PloS one (15-08-2019)
    “…Bacterial invasion of synovial joints, as in infectious or septic arthritis, can be difficult to treat in both veterinary and human clinical practice…”
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    Journal Article
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    The effect of enrofloxacin on enteric Escherichia coli: Fitting a mathematical model to in vivo data by Erwin, Samantha, Foster, Derek M, Jacob, Megan E, Papich, Mark G, Lanzas, Cristina

    Published in PloS one (31-01-2020)
    “…Antimicrobial drugs administered systemically may cause the emergence and dissemination of antimicrobial resistance among enteric bacteria. To develop logical,…”
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    Journal Article
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    Comparative growth dynamics of bacterial and fungal contaminants in bupivacaine liposomal injectable suspension, bupivacaine 0.5%, and propofol by Wallace, Amber, Love, Lydia, Gensler, Catherine, Jacob, Megan, Robertson, James, Messenger, Kristen

    Published in PloS one (16-02-2023)
    “…To determine whether bupivacaine liposomal injectable suspension (BLIS) supports microbial growth when artificially inoculated and to evaluate liposomal…”
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    Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers by Foster, Derek M, Jacob, Megan E, Farmer, Kyle A, Callahan, Benjamin J, Theriot, Casey M, Kathariou, Sophia, Cernicchiaro, Natalia, Prange, Timo, Papich, Mark G

    Published in PloS one (04-10-2019)
    “…Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance in enteric bacteria. Our objective was to determine the…”
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    Gallbladder microbiota in healthy dogs and dogs with mucocele formation by Gookin, Jody L, Hartley, Ashley N, Aicher, Kathleen M, Mathews, Kyle G, Cullen, Rachel, Cullen, John M, Callahan, Benjamin J, Stowe, Devorah M, Seiler, Gabriela S, Jacob, Megan E, Arnold, Jason W, Azcarate-Peril, M Andrea, Stauffer, Stephen H

    Published in PloS one (10-02-2023)
    “…To date studies have not investigated the culture-independent microbiome of bile from dogs, a species where aseptic collection of bile under ultrasound…”
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    Impact of florfenicol dosing regimen on the phenotypic and genotypic resistance of enteric bacteria in steers by Halleran, Jennifer, Sylvester, Hannah, Jacob, Megan, Callahan, Benjamin, Baynes, Ronald, Foster, Derek

    Published in Scientific reports (28-02-2024)
    “…The food animal sector’s use of antimicrobials is heavily critiqued for its role in allowing resistance to develop against critically important antimicrobials…”
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    Continuous sampling of healthy and mastitic quarters of lactating cattle by ultrafiltration after intramammary ceftiofur hydrochloride administration by Mzyk, Danielle A., Halleran, Jennifer L., Sylvester, Hannah J., Giles, Claire B., Jacob, Megan E., Baynes, Ronald E., Foster, Derek M.

    Published in Journal of veterinary internal medicine (01-09-2024)
    “…Background Pharmacological activity of intramammary drugs depends on adequate drug concentrations within the cistern, but sampling is often limited. Insight…”
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    Exploratory cohort study to determine if dry cow vaccination with a Salmonella Newport bacterin can protect dairy calves against oral Salmonella challenge by Foster, Derek, Jacob, Megan, Stowe, Devorah, Smith, Geof

    Published in Journal of veterinary internal medicine (01-07-2019)
    “…Background Salmonellosis is a major cause of morbidity and mortality in neonatal calves, often occurring before preventative vaccines can be administered…”
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    Optimizing a Screening Protocol for Potential Extended-Spectrum β-Lactamase Escherichia coli on MacConkey Agar for Use in a Global Surveillance Program by Jacob, Megan E, Keelara, Shivaramu, Aidara-Kane, Awa, Matheu Alvarez, Jorge R, Fedorka-Cray, Paula J

    Published in Journal of clinical microbiology (24-08-2020)
    “…The increasing prevalence of extended-spectrum beta-lactamase (ESBL)-producing is worrisome. Coordinated efforts to better understand global prevalence and…”
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    Sterility and concentration of liposomal bupivacaine single‐use vial when used in a multiple‐dose manner by Carlson, Alexandra R., Nixon, Emma, Jacob, Megan E., Messenger, Kristen M.

    Published in Veterinary surgery (01-05-2020)
    “…Objective To evaluate the sterility of bupivacaine liposome injectable suspension (Nocita®) used in a multiple‐dose fashion for 5 days. Study design Triplicate…”
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    Comprehensive phenotypic and genotypic characterization and comparison of virulence, biofilm, and antimicrobial resistance in urinary Escherichia coli isolated from canines by Gilbertie, Jessica M., Levent, Gizem, Norman, Keri N., Vinasco, Javier, Scott, H. Morgan, Jacob, Megan E.

    Published in Veterinary microbiology (01-10-2020)
    “…•Canine UTI is dominated by predictable sequence types which carry consistent adaptive survival mechanisms.•Biofilm formation by canine UPECs is positively…”
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    Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single‐use single‐incision laparoscopic surgery port by Scharf, Valery F., Dent, Brian, Jacob, Megan E., Moore, Brandon

    Published in Veterinary surgery (01-06-2019)
    “…Objective To determine the ability of vaporized hydrogen peroxide (VHP) to sterilize a single‐use single‐incision laparoscopic surgery port and its associated…”
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    Microbiome analysis of bile from apparently healthy cats and cats with suspected hepatobiliary disease by Slead, Tanner S., Callahan, Benjamin J., Schreeg, Megan E., Seiler, Gabriela S., Stowe, Devorah M., Azcarate‐Peril, Maria Andrea, Jacob, Megan E., Gookin, Jody L.

    Published in Journal of veterinary internal medicine (01-11-2023)
    “…Background Bacterial infection of bile is a common cause of hepatobiliary disease in cats. Whether bile harbors a core microbiota in health or in cases of…”
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    Platelet‐rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro by Gilbertie, Jessica M., Schaer, Thomas P., Schubert, Alicia G., Jacob, Megan E., Menegatti, Stefano, Ashton Lavoie, R., Schnabel, Lauren V.

    Published in Journal of orthopaedic research (01-06-2020)
    “…Infectious arthritis is difficult to treat in both human and veterinary clinical practice. Recent literature reports Staphylococcus aureus as well as other…”
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    Characteristics of antimicrobial resistance in Escherichia coli isolated from retail meat products in North Carolina by Aworh, Mabel Kamweli, Thakur, Siddhartha, Gensler, Catherine, Harrell, Erin, Harden, Lyndy, Fedorka-Cray, Paula J, Jacob, Megan

    Published in PloS one (05-01-2024)
    “…Escherichia coli is commonly used as an indicator for antimicrobial resistance (AMR) in food, animal, environment, and human surveillance systems. Our study…”
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    Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5‐year retrospective study by Walker, Grayson K., Yustyniuk, Valeriia, Shamoun, John, Jacob, Megan E., Correa, Maria, Vaden, Shelly L., Borst, Luke B.

    Published in Journal of veterinary internal medicine (01-07-2022)
    “…Background Urinary tract infections (UTI) caused by Escherichia coli and Enterococcus spp., which are frequently coisolated in polymicrobial UTI, cause…”
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    Association of Atypical Enteropathogenic Escherichia coli with Diarrhea and Related Mortality in Kittens by Watson, Victoria E, Jacob, Megan E, Flowers, James R, Strong, Sandra J, DebRoy, Chitrita, Gookin, Jody L

    Published in Journal of clinical microbiology (01-09-2017)
    “…Diarrhea is responsible for the death of approximately 900,000 children per year worldwide. In children, typical enteropathogenic (EPEC) is a common cause of…”
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    Diagnostic utility of the total nucleated cell count for differentiation of septic and sterile peritoneal effusions in dogs by DiDomenico, Amy E., Jacob, Megan E., Stowe, Devorah M., Gruber, Erika J.

    Published in Veterinary clinical pathology (01-03-2024)
    “…Background Rapid and accurate diagnosis of septic peritonitis is critical for initiating appropriate medical and surgical management. Objectives The aim of…”
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