Search Results - "Jacob, Megan"
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Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Foodborne Pathogens and Disease
Published in Foodborne pathogens and disease (01-09-2024)Get more information
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Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections
Published in PloS one (15-08-2019)“…Bacterial invasion of synovial joints, as in infectious or septic arthritis, can be difficult to treat in both veterinary and human clinical practice…”
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The effect of enrofloxacin on enteric Escherichia coli: Fitting a mathematical model to in vivo data
Published in PloS one (31-01-2020)“…Antimicrobial drugs administered systemically may cause the emergence and dissemination of antimicrobial resistance among enteric bacteria. To develop logical,…”
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Comparative growth dynamics of bacterial and fungal contaminants in bupivacaine liposomal injectable suspension, bupivacaine 0.5%, and propofol
Published in PloS one (16-02-2023)“…To determine whether bupivacaine liposomal injectable suspension (BLIS) supports microbial growth when artificially inoculated and to evaluate liposomal…”
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Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
Published in PloS one (04-10-2019)“…Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance in enteric bacteria. Our objective was to determine the…”
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Gallbladder microbiota in healthy dogs and dogs with mucocele formation
Published in PloS one (10-02-2023)“…To date studies have not investigated the culture-independent microbiome of bile from dogs, a species where aseptic collection of bile under ultrasound…”
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Impact of florfenicol dosing regimen on the phenotypic and genotypic resistance of enteric bacteria in steers
Published in Scientific reports (28-02-2024)“…The food animal sector’s use of antimicrobials is heavily critiqued for its role in allowing resistance to develop against critically important antimicrobials…”
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Continuous sampling of healthy and mastitic quarters of lactating cattle by ultrafiltration after intramammary ceftiofur hydrochloride administration
Published in Journal of veterinary internal medicine (01-09-2024)“…Background Pharmacological activity of intramammary drugs depends on adequate drug concentrations within the cistern, but sampling is often limited. Insight…”
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Exploratory cohort study to determine if dry cow vaccination with a Salmonella Newport bacterin can protect dairy calves against oral Salmonella challenge
Published in Journal of veterinary internal medicine (01-07-2019)“…Background Salmonellosis is a major cause of morbidity and mortality in neonatal calves, often occurring before preventative vaccines can be administered…”
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Optimizing a Screening Protocol for Potential Extended-Spectrum β-Lactamase Escherichia coli on MacConkey Agar for Use in a Global Surveillance Program
Published in Journal of clinical microbiology (24-08-2020)“…The increasing prevalence of extended-spectrum beta-lactamase (ESBL)-producing is worrisome. Coordinated efforts to better understand global prevalence and…”
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Sterility and concentration of liposomal bupivacaine single‐use vial when used in a multiple‐dose manner
Published in Veterinary surgery (01-05-2020)“…Objective To evaluate the sterility of bupivacaine liposome injectable suspension (Nocita®) used in a multiple‐dose fashion for 5 days. Study design Triplicate…”
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Comprehensive phenotypic and genotypic characterization and comparison of virulence, biofilm, and antimicrobial resistance in urinary Escherichia coli isolated from canines
Published in Veterinary microbiology (01-10-2020)“…•Canine UTI is dominated by predictable sequence types which carry consistent adaptive survival mechanisms.•Biofilm formation by canine UPECs is positively…”
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Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single‐use single‐incision laparoscopic surgery port
Published in Veterinary surgery (01-06-2019)“…Objective To determine the ability of vaporized hydrogen peroxide (VHP) to sterilize a single‐use single‐incision laparoscopic surgery port and its associated…”
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Microbiome analysis of bile from apparently healthy cats and cats with suspected hepatobiliary disease
Published in Journal of veterinary internal medicine (01-11-2023)“…Background Bacterial infection of bile is a common cause of hepatobiliary disease in cats. Whether bile harbors a core microbiota in health or in cases of…”
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Platelet‐rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro
Published in Journal of orthopaedic research (01-06-2020)“…Infectious arthritis is difficult to treat in both human and veterinary clinical practice. Recent literature reports Staphylococcus aureus as well as other…”
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Characteristics of antimicrobial resistance in Escherichia coli isolated from retail meat products in North Carolina
Published in PloS one (05-01-2024)“…Escherichia coli is commonly used as an indicator for antimicrobial resistance (AMR) in food, animal, environment, and human surveillance systems. Our study…”
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Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5‐year retrospective study
Published in Journal of veterinary internal medicine (01-07-2022)“…Background Urinary tract infections (UTI) caused by Escherichia coli and Enterococcus spp., which are frequently coisolated in polymicrobial UTI, cause…”
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Association of Atypical Enteropathogenic Escherichia coli with Diarrhea and Related Mortality in Kittens
Published in Journal of clinical microbiology (01-09-2017)“…Diarrhea is responsible for the death of approximately 900,000 children per year worldwide. In children, typical enteropathogenic (EPEC) is a common cause of…”
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Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6‐year multi‐institution study
Published in Journal of veterinary internal medicine (01-05-2021)“…Background Combatting antimicrobial resistance requires a One Health approach to antimicrobial stewardship including antimicrobial drug (AMD) use evaluation…”
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Diagnostic utility of the total nucleated cell count for differentiation of septic and sterile peritoneal effusions in dogs
Published in Veterinary clinical pathology (01-03-2024)“…Background Rapid and accurate diagnosis of septic peritonitis is critical for initiating appropriate medical and surgical management. Objectives The aim of…”
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