Search Results - "Jacob, Jürgen"

THE SIGNIFICANCE OF POLYCYCLIC AROMATIC HYDROCARBONS AS ENVIRONMENTAL CARCINOGENS. 35 YEARS RESEARCH ON PAH-A RETROSPECTIVE by Jacob, Jürgen

“…In vivo studies with laboratory animals as well as in vitro studies with bacteria and mammalian cell cultures have demonstrated that the mutagenic and/or…”
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Biomonitoring of polycyclic aromatic hydrocarbons in human urine by Jacob, Jürgen, Seidel, Albrecht

“…Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental…”
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Detection of carcinogenic aromatic amines in the urine of non-smokers by Grimmer, Gernot, Dettbarn, Gerhard, Seidel, Albrecht, Jacob, Jürgen

“…Smoking is thought to be one of the most important anthropogenic risk factors involved in the development of urinary bladder cancer in humans. Tobacco smoke…”
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New Biomarkers of Occupational Exposure to Polycyclic Aromatic Hydrocarbons by Seidel, Albrecht, Spickenheuer, Anne, Straif, Kurt, Rihs, Hans-Peter, Marczynski, Boleslaw, Scherenberg, Michael, Dettbarn, Gerhard, Angerer, Jürgen, Wilhelm, Michael, Brüning, Thomas, Jacob, Jürgen, Pesch, Beate

“…Polycyclic aromatic hydrocarbons (PAH) are metabolized in a complex manner. Although biological activity is associated with diol-epoxide formation, phenolic…”
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On the species-specific biotransformation of dibenzo[ a, l]pyrene by Schober, Wolfgang, Luch, Andreas, Soballa, Volker J., Raab, Gottfried, Stegeman, John J., Doehmer, Johannes, Jacob, Jürgen, Seidel, Albrecht

“…We were aimed at investigating the activation of the carcinogenic polycyclic aromatic hydrocarbon (PAH) dibenzo[ a, l]pyrene (DB[ a, l]P) in Chinese hamster…”
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Profile of urinary phenanthrene metabolites in smokers and non-smokers by Jacob, Jurgen, Grimmer, Gernot, Dettbarn, Gerhard

“…Phenanthrene metabolites (phenols and dihydrodiols) and 1-hydroxypyrene excreted in the 24-h urine of smokers, non-smokers and lung cancer patients, who after…”
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Metabolic Activation of Dibenzo[a,l]pyrene by Human Cytochrome P450 1A1 and P450 1B1 Expressed in V79 Chinese Hamster Cells by Luch, Andreas, Schober, Wolfgang, Soballa, Volker J, Raab, Gottfried, Greim, Helmut, Jacob, Jürgen, Doehmer, Johannes, Seidel, Albrecht

“…Metabolic activation of the strongly carcinogenic polycyclic aromatic hydrocarbon (PAH) dibenzo[a,l]pyrene (DB[a,l]P) and its trans-8,9-dihydrodiol…”
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Cytochrome P450-mediated activation of phenanthrene in genetically engineered V79 Chinese hamster cells by Jacob, Jürgen, Raab, Gottfried, Soballa, Volker, Schmalix, Wolfgang A., Grimmer, Gernot, Greim, Helmut, Doehmer, Johannes, Seidel, Albrecht

“…V79 Chinese hamster cells genetically engineered for rat cytochromes P450 1A1, 1A2, 2B1 and human cytochromes P450 1A1, 1A2, 2A6, 2E1, and 3A4 are being…”
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Metabolism and DNA-Binding of 3-Nitrobenzanthrone in Primary Rat Alveolar Type II Cells, in Human Fetal Bronchial, Rat Epithelial and Mesenchymal Cell Lines by Borlak, Jürgen, Hansen, Tanja, Yuan, Zhi-Xin, Sikka, Harish C., Kumar, Subodh, Schmidbauer, Stefan, Frank, Heinz, Jacob, Jürgen, Seidel, Albrecht

“…3-Nitrobenzanthrone (NBA) is a suspected human carcinogen and has been identified in diesel exhaust and in airborne particulates. Human exposure to NBA is…”
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Early recognition of high quality researchers of the German psychiatry by worldwide accessible bibliometric indicators by HARALD JACOB, Jürgen, LEHRL, Siegfried, WOLFRAM HENKEL, Andreas

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Regio- and stereoselectivity in the metabolism of benzo[ c]phenanthrene mediated by genetically engineered V79 Chinese hamster cells expressing rat and human cytochromes P450 by Seidel, Albrecht, Soballa, Volker J, Raab, Gottfried, Frank, Heinz, Greim, Helmut, Grimmer, Gernot, Jacob, Jürgen, Doehmer, Johannes

“…Regio- and stereoselective metabolism mediated by cytochrome P450 (CYP) and metabolite-dependent cytotoxicity of benzo[ c]phenanthrene (B[ c]Ph) and its…”
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The significance of polycyclic aromatic hydrocarbons as environmental carcinogens by Jacob, J.

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Interaction between Metabolism and Transport of Benzo[ a]pyrene and Its Metabolites in Enterocytes by Buesen, Roland, Mock, Melissa, Seidel, Albrecht, Jacob, Jürgen, Lampen, Alfonso

“…Epithelial cells of the small intestine are responsible for the resorption of different food components as well as potentially toxic agents such as benzo[…”
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Analysis of the polycyclic aromatic hydrocarbon content of petrol and diesel engine lubricating oils and determination of DNA adducts in topically treated mice by 32P-postlabelling by Carmichael, P L, Jacob, J, Grimmer, G, Phillips, D H

“…Engine lubricating oils are known to accumulate carcinogenic polycyclic aromatic hydrocarbons (PAHs) during engine running. Oils from nine petrol-powered and…”
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Chemical composition of uropygial gland secretions of owls by Jacob, J, Poltz, J

“…The compositions of the uropygial gland secretions of the long-eared owl, eagle owl, and barn owl have been determined. The waxes of the first two owls, which…”
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Occurrence of positional isomers of octadecenoic and hexadecenoic acids in human depot fat by Jacob, J, Grimmer, G

“…Positional isomers of hexadecenoic aud octadecenoic acids of human adipose tissue have been separated by gas-liquid chromatography and their amounts determined…”
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Structure and amount of positional isomers of monounsaturated fatty acids in human depot fat by Jacob, J, Grimmer, G

“…Positional isomers of decenoic, dodecenoic, and tetradecenoic acids of human adipose tissue have been separated by gas-liquid chromatography and their amounts…”
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Chemistry of the uropygial gland secretion of Hume’s ground jay Pseudopodoces humilis and its taxonomic implications by Gebauer, Axel, Jacob, Jürgen, Kaiser, Martin, Eck, Siegfried

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The Structure of Preen Gland Waxes from Pelecaniform Birds Containing 3,7-Dimethyloctan-1-ol -an Active Ingredient against Dermatophytes by Jacob, Jürgen, Eigener, Ulrich, Hoppe, Udo

“…A biologically active principle has been isolated from the uropygial gland secretion of the gannet (Sula bassana) exhibiting growth inhibitory activity for…”
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2,3-Dihydroxy Fatty Acids-Containing Waxes in Storks (C iconiidae) by Jacob, Jürgen, Raab, Gottfried

“…Uropygial gland secretions from five out of a total of seven species forming the genus Ciconia (family Ciconiidae; order Ciconiiformes) were found to consist…”
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