Search Results - "Jacob, Annlin"

The CCR5 Gene Edited CD34 + CD90 + Hematopoietic Stem Cell Population Serves as an Optimal Graft Source for HIV Gene Therapy by Karuppusamy, Karthik V, Demosthenes, John Paul, Venkatesan, Vigneshwaran, Christopher, Abisha Crystal, Babu, Prathibha, Azhagiri, Manojkumar K, Jacob, Annlin, Ramalingam, Veena Vadhini, Rangaraj, Sumathi, Murugesan, Mohankumar Kumarasamypet, Marepally, Srujan Kumar, Varghese, George M, Srivastava, Alok, Kannangai, Rajesh, Thangavel, Saravanabhavan

“…Transplantation of allogenic hematopoietic stem and progenitor cells (HSPCs) with C-C chemokine receptor type 5 (CCR5) Δ32 genotype generates HIV-1 resistant…”
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Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies by Venkatesan, Vigneshwaran, Christopher, Abisha Crystal, Rhiel, Manuel, Azhagiri, Manoj Kumar K., Babu, Prathibha, Walavalkar, Kaivalya, Saravanan, Bharath, Andrieux, Geoffroy, Rangaraj, Sumathi, Srinivasan, Saranya, Karuppusamy, Karthik V., Jacob, Annlin, Bagchi, Abhirup, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Balasubramanian, Poonkuzhali, Pai, Rekha, Marepally, Srujan Kumar, Mohankumar, Kumarasamypet Murugesan, Velayudhan, Shaji R., Boerries, Melanie, Notani, Dimple, Cathomen, Toni, Srivastava, Alok, Thangavel, Saravanabhavan

“…Reactivation of fetal hemoglobin (HbF) is a commonly adapted strategy to ameliorate β-hemoglobinopathies. However, the continued production of defective adult…”
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