Search Results - "Jaco, Isabel"

SUMO-mediated regulation of NLRP3 modulates inflammasome activity by Barry, Rachael, John, Sidonie Wicky, Liccardi, Gianmaria, Tenev, Tencho, Jaco, Isabel, Chen, Chih-Hong, Choi, Justin, Kasperkiewicz, Paulina, Fernandes-Alnemri, Teresa, Alnemri, Emad, Drag, Marcin, Chen, Yuan, Meier, Pascal

“…The NLRP3 inflammasome responds to infection and tissue damage, and rapidly escalates the intensity of inflammation by activating interleukin (IL)-1β, IL-18…”
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MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death by Jaco, Isabel, Annibaldi, Alessandro, Lalaoui, Najoua, Wilson, Rebecca, Tenev, Tencho, Laurien, Lucie, Kim, Chun, Jamal, Kunzah, Wicky John, Sidonie, Liccardi, Gianmaria, Chau, Diep, Murphy, James M., Brumatti, Gabriela, Feltham, Rebecca, Pasparakis, Manolis, Silke, John, Meier, Pascal

“…TNF is an inflammatory cytokine that upon binding to its receptor, TNFR1, can drive cytokine production, cell survival, or cell death. TNFR1 stimulation causes…”
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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases by Murchison, Elizabeth, Benetti, Roberta, Klatt, Peter, Gonzalez, Susana, Hannon, Gregory, Andl, Thomas, Li, En, Schoeftner, Stefan, Serrano, Manuel, Blasco, Maria A, Muñoz, Purificación, Millar, Sarah, Gonzalo, Susana, Jaco, Isabel, Chen, Taiping

“…Dicer initiates RNA interference by generating small RNAs involved in various silencing pathways. Dicer participates in centromeric silencing, but its role in…”
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Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination by Benetti, Roberta, Gonzalo, Susana, Jaco, Isabel, Schotta, Gunnar, Klatt, Peter, Jenuwein, Thomas, Blasco, María A

“…Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated histone H4 at lysine 20…”
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BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping by Tarsounas, Madalena, Badie, Sophie, Escandell, Jose M, Bouwman, Peter, Carlos, Ana Rita, Thanasoula, Maria, Gallardo, Maria M, Suram, Anitha, Jaco, Isabel, Benitez, Javier, Herbig, Utz, Blasco, Maria A, Jonkers, Jos

“…Mutations in BRCA2 are associated with higher susceptibility to some forms of cancer. BRCA2 is known to play a central role in the repair of DNA breaks via…”
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Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1’s Cytotoxic Potential by Feltham, Rebecca, Jamal, Kunzah, Tenev, Tencho, Liccardi, Gianmaria, Jaco, Isabel, Domingues, Celia Monteiro, Morris, Otto, John, Sidonie Wicky, Annibaldi, Alessandro, Widya, Marcella, Kearney, Conor J., Clancy, Danielle, Elliott, Paul R., Glatter, Timo, Qiao, Qi, Thompson, Andrew J., Nesvizhskii, Alexey, Schmidt, Alexander, Komander, David, Wu, Hao, Martin, Seamus, Meier, Pascal

“…Tumor necrosis factor (TNF) is an inflammatory cytokine that can signal cell survival or cell death. The mechanisms that switch between these distinct outcomes…”
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Global chromatin compaction limits the strength of the DNA damage response by Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A, Skoultchi, Arthur I, Fernandez-Capetillo, Oscar

“…In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact…”
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Centromere mitotic recombination in mammalian cells by Jaco, Isabel, Canela, Andrés, Vera, Elsa, Blasco, Maria A

“…Centromeres are special structures of eukaryotic chromosomes that hold sister chromatid together and ensure proper chromosome segregation during cell division…”
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Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2 by Dantzer, Françoise, Giraud-Panis, Marie-Josèphe, Jaco, Isabel, Amé, Jean-Christophe, Schultz, Inès, Blasco, Maria, Koering, Catherine-Elaine, Gilson, Eric, Ménissier-de Murcia, Josiane, de Murcia, Gilbert, Schreiber, Valérie

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of Mammalian Rad54 in Telomere Length Maintenance by Jaco, Isabel, Muñoz, Purificación, Goytisolo, Fermín, Wesoly, Joanna, Bailey, Susan, Taccioli, Guillermo, Blasco, María A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers by Ferretti, Stephane, Hamon, Jacques, de Kanter, Ruben, Scheufler, Clemens, Andraos-Rey, Rita, Barbe, Stephanie, Bechter, Elisabeth, Blank, Jutta, Bordas, Vincent, Dammassa, Ernesta, Decker, Andrea, Di Nanni, Noemi, Dourdoigne, Marion, Gavioli, Elena, Hattenberger, Marc, Heuser, Alisa, Hemmerlin, Christelle, Hinrichs, Jürgen, Kerr, Grainne, Laborde, Laurent, Jaco, Isabel, Núñez, Eloísa Jiménez, Martus, Hans-Joerg, Quadt, Cornelia, Reschke, Markus, Romanet, Vincent, Schaeffer, Fanny, Schoepfer, Joseph, Schrapp, Maxime, Strang, Ross, Voshol, Hans, Wartmann, Markus, Welly, Sarah, Zécri, Frédéric, Hofmann, Francesco, Möbitz, Henrik, Cortés-Cros, Marta

“…The Werner syndrome RecQ helicase WRN was identified as a synthetic lethal target in cancer cells with microsatellite instability (MSI) by several genetic…”
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The anticonvulsive Phenhydan® suppresses extrinsic cell death by Moerke, Caroline, Jaco, Isabel, Dewitz, Christin, Müller, Tammo, Jacobsen, Annette V., Gautheron, Jérémie, Fritsch, Jürgen, Schmitz, Jessica, Bräsen, Jan Hinrich, Günther, Claudia, Murphy, James M., Kunzendorf, Ulrich, Meier, Pascal, Krautwald, Stefan

“…Different forms of regulated cell death-like apoptosis and necroptosis contribute to the pathophysiology of clinical conditions including ischemia-reperfusion…”
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DNA methyltransferases control telomere length and telomere recombination in mammalian cells by Blasco, María A, Gonzalo, Susana, Jaco, Isabel, Fraga, Mario F, Chen, Taiping, Li, En, Esteller, Manel

“…Here, we describe a role for mammalian DNA methyltransferases (DNMTs) in telomere length control. Mouse embryonic stem (ES) cells genetically deficient for…”
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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases by Benetti, Roberta, Gonzalo, Susana, Jaco, Isabel, Muñoz, Purificación, Gonzalez, Susana, Schoeftner, Stefan, Murchison, Elizabeth, Andl, Thomas, Chen, Taiping, Klatt, Peter, Li, En, Serrano, Manuel, Millar, Sarah, Hannon, Gregory, Blasco, Maria A

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Role of human Ku86 in telomere length maintenance and telomere capping by JACO, Isabel, MUNOZ, Purificacion, BLASCO, Maria A

“…The role of Ku86 at telomeres has been extensively studied in various organisms; however, a role for Ku86 at human telomeres was unknown because Ku86 deletion…”
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Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts by MARTIN, Marta, GENESCA, Anna, LATRE, Laura, JACO, Isabel, TACCIOLI, Guillermo E, EGOZCUE, Josep, BLASCO, Maria A, ILIAKIS, George, TUSELL, Laura

“…Combined cytogenetic and biochemical approaches were used to investigate the contributions of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs)…”
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Corrigendum: a mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases by Benetti, Roberta, Gonzalo, Susana, Jaco, Isabel, Munoz, Purificacion, Gonzalez, Susana, Schoeftner, Stefan, Murchison, Elizabeth, Andl, Thomas, Chen, Taiping, Klatt, Peter, Li, En, Serrano, Manuel, Millar, Sarah, Hannon, Gregory, Blasco, Maria A

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Erratum: A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases by Benetti, Roberta, Gonzalo, Susana, Jaco, Isabel, Muñoz, Purificación, Gonzalez, Susana, Schoeftner, Stefan, Murchison, Elizabeth, Andl, Thomas, Chen, Taiping, Klatt, Peter, Li, En, Serrano, Manuel, Millar, Sarah, Hannon, Gregory, Blasco, Maria A

“…Nat. Struct. Mol. Biol. 15, 268–279 (2008); published online 2 March 2008; corrected after print 18 June 2008 In the version of this article initially…”
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Navigating the landscape of tourism, leisure, and sport studies in Mexico by Monterrubio, Carlos, Dashper, Katherine, Wadham, Helen, Chávez-Dagostino, Rosa María, Martínez Moreno, Omaira Cecilia, Pérez, Javier, Ramírez-Hernández, Omar I., Ruiz Andrade, José Gabriel, Rosas-Jaco, M. Isabel, Silva, Sandy

“…Research in tourism, leisure, and sports in Mexico is justified by the country's rich cultural, natural, and traditional diversity, as well as its economic and…”
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Triplet repeats, RNA secondary structure and toxic gain-of-function models for pathogenesis by GALVAO, Rui, MENDES-SOARES, Luis, CAMARA, Joana, JACO, Isabel, CARMO-FONSECA, Maria

“…Ten years after the discovery of human diseases caused by trinucleotide repeat expansions, searching for mechanistic links between gene mutation and…”
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