Search Results - "Jackson, Trevor R."

Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis by Jones, Dylan T., Ganeshaguru, Kanagasabai, Anderson, Robert J., Jackson, Trevor R., Bruckdorfer, K. Richard, Low, Sylvia Y., Palmqvist, Lars, Prentice, H. Grant, Hoffbrand, A. Victor, Mehta, Atul B., Wickremasinghe, R. Gitendra

“…Activation of the phosphatidylinositol 3- kinase/AKT pathway antagonizes apoptosis in diverse cellular systems. We previously showed that human plasma…”
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Cytohesins and centaurins control subcellular trafficking of macromolecular signaling complexes: regulation by phosphoinositides and ADP-ribosylation factors by Hawadle, Muhamed A, Folarin, Najeem, Martin, Rosemary, Jackson, Trevor R

“…The ADP-ribosylation factor family of small GTP-binding proteins are implicated in the regulation of vesicular transport and control of cytoskeletal and cell…”
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ACAPs Are Arf6 GTPase-Activating Proteins That Function in the Cell Periphery by Jackson, Trevor R., Brown, Fraser D., Nie, Zhongzhen, Miura, Koichi, Foroni, Letizia, Sun, Jianlan, Hsu, Victor W., Donaldson, Julie G., Randazzo, Paul A.

“…The GTP-binding protein ADP-ribosylation factor 6 (Arf6) regulates endosomal membrane trafficking and the actin cytoskeleton in the cell periphery…”
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Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling by Jackson, Trevor R, Kearns, Brian G, Theibert, Anne B

“…Receptor-activated phosphoinositide (PI) 3-kinases produce PtdIns(3,4,5) P 3 and its metabolite PtdIns(3,4) P 2 that function as second messengers in membrane…”
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Identification of a specific lns(l,3,4,5)P4-binding protein as a member of the GAP1 family by Cullen, Peter J., Hsuan, J. Justin, Truong, Oanh, Letcher, Andrew J., Jackson, Trevor R., Dawson, Alan P., Irvine, Robin F.

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GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitro by Blader, I J, Cope, M J, Jackson, T R, Profit, A A, Greenwood, A F, Drubin, D G, Prestwich, G D, Theibert, A B

“…Recent cloning of a rat brain phosphatidylinositol 3,4, 5-trisphosphate binding protein, centaurin alpha, identified a novel gene family based on homology to…”
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Phosphoinositide-dependent Activation of the ADP-ribosylation Factor GTPase-activating Protein ASAP1 by Kam, Jeanelle L., Miura, Koichi, Jackson, Trevor R., Gruschus, James, Roller, Peter, Stauffer, Stacey, Clark, Jenny, Aneja, Rajindra, Randazzo, Paul A.

“…The ADP-ribosylation factor (Arf) family of GTP-binding proteins are regulators of membrane traffic and the actin cytoskeleton. Both negative and positive…”
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Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1 by VENKATESWARLU, Kanamarlapudi, OATEY, Paru B., TAVARÉ, Jeremy M., JACKSON, Trevor R., CULLEN, Peter J.

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Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric site by Kam, J L, Miura, K, Jackson, T R, Gruschus, J, Roller, P, Stauffer, S, Clark, J, Aneja, R, Randazzo, P A

“…The ADP-ribosylation factor (Arf) family of GTP-binding proteins are regulators of membrane traffic and the actin cytoskeleton. Both negative and positive…”
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1-Phosphatidylinositol 3-Kinase Activity is Required for Insulin-Stimulated Glucose Transport But not for RAS Activation in CHO Cells by Hara, K, Yonezawa, K, Sakaue, H, Ando, A, Kotani, K, Kitamura, T, Kitamura, Y, Ueda, H, Stephens, L, Jackson, T R

“…Insulin stimulation drives the formation of a complex between tyrosine-phosphorylated insulin receptor substrate 1 (IRS-1) and 1-phosphatidylinositol 3-kinase…”
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Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain by Hammonds-Odie, L P, Jackson, T R, Profit, A A, Blader, I J, Turck, C W, Prestwich, G D, Theibert, A B

“…Using an affinity resin and photoaffinity label based on phospholipid analogs of inositol 1,3,4,5-tetrakisphosphate (InsP4), we have isolated, characterized,…”
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Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins by Dubois, Thierry, Kerai, Preeti, Zemlickova, Eva, Howell, Steven, Jackson, Trevor R., Venkateswarlu, Kanamarlapudi, Cullen, Peter J., Theibert, Anne B., Larose, Louise, Roach, Peter J., Aitken, Alastair

“…Mammalian casein kinases I (CKI) belong to a family of serine/threonine protein kinases involved in diverse cellular processes including cell cycle…”
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Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase by Jackson, T R, Blader, I J, Hammonds-Odie, L P, Burga, C R, Cooke, F, Hawkins, P T, Wolf, A G, Heldman, K A, Theibert, A B

“…Application of nerve growth factor (NGF) to PC12 cells stimulates a programme of physiological changes leading to the development of a sympathetic neuron like…”
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The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s) by STEPHENS, L, RADENBERG, T, THIEL, U, VOGEL, G, KAY-HOOI KHOO, DELL, A, JACKSON, T. R, HAWKINS, P. T, MAYR, G. W

“…A new class of inositol phosphates containing energy-rich pyrophosphoryl residues has been characterized. D/L-1-Diphosphoinositol pentakisphosphate(s) and…”
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Assay and purification of phosphoinositide-dependent ADP-ribosylation factor (ARF) GTPase activating proteins by Randazzo, P A, Miura, K, Jackson, T R

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Receptor specificity of growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells by JACKSON, T. R, STEPHENS, L. R, HAWKINS, P. T

“…We have investigated synthesis of 3-phosphorylated inositol lipids in growth factor-stimulated Swiss 3T3 cells. Those growth factors tested which act via…”
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Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins by Thierry Dubois, Preeti Kerai, Eva Zemlickova, Steven Howell, Trevor R. Jackson, Kanamarlapudi Venkateswarlu, Peter J. Cullen, Anne B. Theibert, Louise Larose, Peter J. Roach, Alastair Aitken

“…Mammalian casein kinases I (CKI) belong to a family of serine/threonine protein kinases involved in diverse cellular processes including cell cycle…”
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Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1 by VENKATESWARLU, Kanamarlapudi, OATEY, Paru B., TAVARÉ, Jeremy M., JACKSON, Trevor R., CULLEN, Peter J.

“…Centaurin-α is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-α1, a human…”
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Simultaneous Measurements of Cytosolic Calcium and Secretion in Single Bovine Adrenal Chromaffin Cells by Fluorescent Imaging of Fura-2 in Cocultured Cells by Cheek, Timothy R., Jackson, Trevor R., O'Sullivan, Antony J., Moreton, Roger B., Berridge, Michael J., Burgoyne, Robert D.

“…The cytosolic free calcium concentration ([ Ca2+] i) and exocytosis of chromaffin granules were measured simultaneously from single, intact bovine adrenal…”
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Tumor promoter 12-O-tetradecanoylphorbol 13-acetate inhibits mas/angiotensin receptor-stimulated inositol phosphate production and intracellular Ca 2+ elevation in the 401L-C3 neuronal cell line by Jackson, Trevor R., Hanley, Michael R.

“…Stimulation of mas-oncogene transfected 401L-C3 cells by angiotensins leads to the production of inositol phosphates. This response shows dose dependence, and…”
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