Search Results - "Jackson, Laurence"

Deformable Slice-to-Volume Registration for Motion Correction of Fetal Body and Placenta MRI by Uus, Alena, Zhang, Tong, Jackson, Laurence H., Roberts, Thomas A., Rutherford, Mary A., Hajnal, Joseph V., Deprez, Maria

“…In in-utero MRI, motion correction for fetal body and placenta poses a particular challenge due to the presence of local non-rigid transformations of organs…”
Get full text

Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta by Slator, Paddy J., Hutter, Jana, Palombo, Marco, Jackson, Laurence H., Ho, Alison, Panagiotaki, Eleftheria, Chappell, Lucy C., Rutherford, Mary A., Hajnal, Joseph V., Alexander, Daniel C.

“…Purpose A combined diffusion‐relaxometry MR acquisition and analysis pipeline for in vivo human placenta, which allows for exploration of coupling between T2*…”
Get full text

T2 Placental Magnetic Resonance Imaging in Preterm Preeclampsia: An Observational Cohort Study by Ho, Alison E.P., Hutter, Jana, Jackson, Laurence H., Seed, Paul T., Mccabe, Laura, Al-Adnani, Mudher, Marnerides, Andreas, George, Simi, Story, Lisa, Hajnal, Joseph V., Rutherford, Mary A., Chappell, Lucy C.

“…Placental dysfunction underlies the cause of pregnancies complicated by preeclampsia. The use of placental magnetic resonance imaging to provide an insight…”
Get full text

Systematic evaluation of velocity‐selective arterial spin labeling settings for placental perfusion measurement by Harteveld, Anita A., Hutter, Jana, Franklin, Suzanne L., Jackson, Laurence H., Rutherford, Mary, Hajnal, Joseph V., Osch, Matthias J. P., Bos, Clemens, De Vita, Enrico

“…Purpose Placental function is key for successful human pregnancies. Perfusion may be a sensitive marker for the in vivo assessment of placental function…”
Get full text

Fetal whole heart blood flow imaging using 4D cine MRI by Roberts, Thomas A., van Amerom, Joshua F. P., Uus, Alena, Lloyd, David F. A., van Poppel, Milou P. M., Price, Anthony N., Tournier, Jacques-Donald, Mohanadass, Chloe A., Jackson, Laurence H., Malik, Shaihan J., Pushparajah, Kuberan, Rutherford, Mary A., Razavi, Reza, Deprez, Maria, Hajnal, Joseph V.

“…Prenatal detection of congenital heart disease facilitates the opportunity for potentially life-saving care immediately after the baby is born…”
Get full text

Data-Driven multi-Contrast spectral microstructure imaging with InSpect: INtegrated SPECTral component estimation and mapping by Slator, Paddy J., Hutter, Jana, Marinescu, Razvan V., Palombo, Marco, Jackson, Laurence H., Ho, Alison, Chappell, Lucy C., Rutherford, Mary, Hajnal, Joseph V., Alexander, Daniel C.

“…•Unsupervised learning technique for spectroscopic analysis of quantitative MRI.•Shares information across voxels to improve estimation of multi-dimensional or…”
Get full text

An efficient and combined placental T1‐ADC acquisition in pregnancies with and without pre‐eclampsia by Hutter, Jana, Ho, Alison, Jackson, Laurence H., Slator, Paddy J., Chappell, Lucy C., Hajnal, Joseph V., Rutherford, Mary A.

“…Purpose To provide a new approach to jointly assess microstructural and molecular properties of the human placenta in vivo fast and efficiently and to present…”
Get full text

Perfusion and apparent oxygenation in the human placenta (PERFOX) by Hutter, Jana, Harteveld, Anita A., Jackson, Laurence H., Franklin, Suzanne, Bos, Clemens, Osch, Matthias J. P., O'Muircheartaigh, Jonathan, Ho, Alison, Chappell, Lucy, Hajnal, Joseph V., Rutherford, Mary, De Vita, Enrico

“…Purpose To study placental function—both perfusion and an oxygenation surrogate (T2*)—simultaneously and quantitatively in‐vivo. Methods Fifteen pregnant women…”
Get full text

Non-invasive mapping of human placenta microenvironments throughout pregnancy with diffusion-relaxation MRI by Slator, Paddy J, Cromb, Daniel, Jackson, Laurence H, Ho, Alison, Counsell, Serena J, Story, Lisa, Chappell, Lucy C, Rutherford, Mary, Hajnal, Joseph V, Hutter, Jana, Alexander, Daniel C

“…In-vivo measurements of placental structure and function have the potential to improve prediction, diagnosis, and treatment planning for a wide range of…”
Get full text

Complex Congenital Heart Disease Associated With Disordered Myocardial Architecture in a Midtrimester Human Fetus by Garcia-Canadilla, Patricia, Dejea, Hector, Bonnin, Anne, Balicevic, Vedrana, Loncaric, Sven, Zhang, Chong, Butakoff, Constantine, Aguado-Sierra, Jazmin, Vázquez, Mariano, Jackson, Laurence H, Stuckey, Daniel J, Rau, Cristoph, Stampanoni, Marco, Bijnens, Bart, Cook, Andrew C

“…In the era of increasingly successful corrective interventions in patients with congenital heart disease (CHD), global and regional myocardial remodeling are…”
Get full text

Author Correction: Fetal whole heart blood flow imaging using 4D cine MRI by Roberts, Thomas A., van Amerom, Joshua F. P., Uus, Alena, Lloyd, David F. A., van Poppel, Milou P. M., Price, Anthony N., Tournier, Jacques-Donald, Mohanadass, Chloe A., Jackson, Laurence H., Malik, Shaihan J., Pushparajah, Kuberan, Rutherford, Mary A., Razavi, Reza, Deprez, Maria, Hajnal, Joseph V.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20353-3…”
Get full text

In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques by Shangaris, Panicos, Loukogeorgakis, Stavros P., Subramaniam, Sindhu, Flouri, Christina, Jackson, Laurence H., Wang, Wei, Blundell, Michael P., Liu, Shanrun, Eaton, Simon, Bakhamis, Nahla, Ramachandra, Durrgah Latchumi, Maghsoudlou, Panayiotis, Urbani, Luca, Waddington, Simon N., Eddaoudi, Ayad, Archer, Joy, Antoniou, Michael N., Stuckey, Daniel J., Schmidt, Manfred, Thrasher, Adrian J., Ryan, Thomas M., De Coppi, Paolo, David, Anna L.

“…In utero gene therapy (IUGT) to the fetal hematopoietic compartment could be used to treat congenital blood disorders such as β-thalassemia. A humanised mouse…”
Get full text

Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia by Jackson, Laurence H., Vlachodimitropoulou, Evangelia, Shangaris, Panicos, Roberts, Thomas A., Ryan, Thomas M., Campbell-Washburn, Adrienne E., David, Anna L., Porter, John B., Lythgoe, Mark F., Stuckey, Daniel J.

“…β-thalassemia (βT) is a genetic blood disorder causing profound and life threatening anemia. Current clinical management of βT is a lifelong dependence on…”
Get full text

Publisher Correction: In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques by Shangaris, Panicos, Loukogeorgakis, Stavros P., Subramaniam, Sindhu, Flouri, Christina, Jackson, Laurence H., Wang, Wei, Blundell, Michael P., Liu, Shanrun, Eaton, Simon, Bakhamis, Nahla, Ramachandra, Durrgah Latchumi, Maghsoudlou, Panayiotis, Urbani, Luca, Waddington, Simon N., Eddaoudi, Ayad, Archer, Joy, Antoniou, Michael N., Stuckey, Daniel J., Schmidt, Manfred, Thrasher, Adrian J., Ryan, Thomas M., De Coppi, Paolo, David, Anna L.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Automated decision making in Barrett’s oesophagus: development and deployment of a natural language processing tool by Zecevic, Agathe, Jackson, Laurence, Zhang, Xinyue, Pavlidis, Polychronis, Dunn, Jason, Trudgill, Nigel, Ahmed, Shahd, Visaggi, Pierfrancesco, YoonusNizar, Zanil, Roberts, Angus, Zeki, Sebastian S.

“…Manual decisions regarding the timing of surveillance endoscopy for premalignant Barrett’s oesophagus (BO) is error-prone. This leads to inefficient resource…”
Get full text

Myocardial Viability Imaging using Manganese‐Enhanced MRI in the First Hours after Myocardial Infarction by Jasmin, Nur Hayati, Thin, May Zaw, Johnson, Robert D., Jackson, Laurence H., Roberts, Thomas A., David, Anna L., Lythgoe, Mark F., Yang, Philip C., Davidson, Sean M., Camelliti, Patrizia, Stuckey, Daniel J.

“…Early measurements of tissue viability after myocardial infarction (MI) are essential for accurate diagnosis and treatment planning but are challenging to…”
Get full text

Direct comparison of high‐temporal‐resolution CINE MRI with Doppler ultrasound for assessment of diastolic dysfunction in mice by Roberts, Thomas A., Price, Anthony N., Jackson, Laurence H., Taylor, Valerie, David, Anna L., Lythgoe, Mark F., Stuckey, Daniel J.

“…Diastolic dysfunction is a sensitive early indicator of heart failure and can provide additional data to conventional measures of systolic function…”
Get full text

Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment by Speidel, Alessondra T, Stuckey, Daniel J, Chow, Lesley W, Jackson, Laurence H, Noseda, Michela, Abreu Paiva, Marta, Schneider, Michael D, Stevens, Molly M

“…Retention and survival of transplanted cells are major limitations to the efficacy of regenerative medicine, with short-term paracrine signals being the…”
Get full text

Integrated and efficient diffusion-relaxometry using ZEBRA by Hutter, Jana, Slator, Paddy J., Christiaens, Daan, Teixeira, Rui Pedro A. G., Roberts, Thomas, Jackson, Laurence, Price, Anthony N., Malik, Shaihan, Hajnal, Joseph V.

“…The emergence of multiparametric diffusion models combining diffusion and relaxometry measurements provides powerful new ways to explore tissue microstructure,…”
Get full text

An efficient and combined placental ‐ADC acquisition in pregnancies with and without pre‐eclampsia by Hutter, Jana, Ho, Alison, Jackson, Laurence H., Slator, Paddy J., Chappell, Lucy C., Hajnal, Joseph V., Rutherford, Mary A.

Get full text