Search Results - "Jackson, Johanna S."

Altered Synapse Stability in the Early Stages of Tauopathy by Jackson, Johanna S., Witton, Jonathan, Johnson, James D., Ahmed, Zeshan, Ward, Mark, Randall, Andrew D., Hutton, Michael L., Isaac, John T., O’Neill, Michael J., Ashby, Michael C.

“…Synapse loss is a key feature of dementia, but it is unclear whether synaptic dysfunction precedes degenerative phases of the disease. Here, we show that even…”
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Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study by Jackson, Johanna S, Golding, Jon P, Chapon, Catherine, Jones, William A, Bhakoo, Kishore K

“…This study aimed to determine the homing potential and fate of epidermal neural crest stem cells (eNCSCs) derived from hair follicles, and bone marrow-derived…”
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Pinpointing the locus of GABAergic vulnerability in Alzheimer’s disease by Melgosa-Ecenarro, Leire, Doostdar, Nazanin, Radulescu, Carola I., Jackson, Johanna S., Barnes, Samuel J.

“…The early stages of Alzheimer’s disease (AD) have been linked to microcircuit dysfunction and pathophysiological neuronal firing in several brain regions…”
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Characterisation of premature cell senescence in Alzheimer’s disease using single nuclear transcriptomics by Fancy, Nurun N., Smith, Amy M., Caramello, Alessia, Tsartsalis, Stergios, Davey, Karen, Muirhead, Robert C. J., McGarry, Aisling, Jenkyns, Marion H., Schneegans, Eleonore, Chau, Vicky, Thomas, Michael, Boulger, Sam, Cheung, To Ka Dorcas, Adair, Emily, Papageorgopoulou, Marianna, Willumsen, Nanet, Khozoie, Combiz, Gomez-Nicola, Diego, Jackson, Johanna S., Matthews, Paul M.

“…Aging is associated with cell senescence and is the major risk factor for AD. We characterized premature cell senescence in postmortem brains from non-diseased…”
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Mass spectrometry imaging highlights dynamic patterns of lipid co‐expression with Aβ plaques in mouse and human brains by Huang, Helen Xuexia, Inglese, Paolo, Tang, Jiabin, Yagoubi, Riad, Correia, Gonçalo D. S., Horneffer‐van der Sluis, Verena M., Camuzeaux, Stephane, Wu, Vincen, Kopanitsa, Maksym V., Willumsen, Nanet, Jackson, Johanna S., Barron, Anna M., Saito, Takashi, Saido, Takaomi C., Gentlemen, Steve, Takats, Zoltan, Matthews, Paul M.

“…Lipids play crucial roles in the susceptibility and brain cellular responses to Alzheimer's disease (AD) and are increasingly considered potential soluble…”
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Imbalance in the response of pre- and post-synaptic components to amyloidopathy by Stephen, Terri-Leigh, Tamagnini, Francesco, Piegsa, Judith, Sung, Katherine, Harvey, Joshua, Oliver-Evans, Alice, Murray, Tracey K., Ahmed, Zeshan, Hutton, Michael L., Randall, Andrew, O’Neill, Michael J., Jackson, Johanna S.

“…Alzheimer’s disease (AD)-associated synaptic dysfunction drives the progression of pathology from its earliest stages. Amyloid β (Aβ) species, both soluble and…”
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A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease by Tsartsalis, Stergios, Sleven, Hannah, Fancy, Nurun, Wessely, Frank, Smith, Amy M., Willumsen, Nanet, Cheung, To Ka Dorcas, Rokicki, Michal J., Chau, Vicky, Ifie, Eseoghene, Khozoie, Combiz, Ansorge, Olaf, Yang, Xin, Jenkyns, Marion H., Davey, Karen, McGarry, Aisling, Muirhead, Robert C. J., Debette, Stephanie, Jackson, Johanna S., Montagne, Axel, Owen, David R., Miners, J. Scott, Love, Seth, Webber, Caleb, Cader, M. Zameel, Matthews, Paul M.

“…Brain perfusion and blood-brain barrier (BBB) integrity are reduced early in Alzheimer’s disease (AD). We performed single nucleus RNA sequencing of vascular…”
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Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment by Wood, James C., Jackson, Johanna S., Jakubs, Katherine, Chapman, Katie Z., Ekdahl, Christine T., Kokaia, Zaal, Kokaia, Merab, Lindvall, Olle

“…We have previously shown that following severe brain insults, chronic inflammation induced by lipopolysaccharide (LPS) injection, and status epilepticus, new…”
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An In Vivo Multimodal Imaging Study Using MRI and PET of Stem Cell Transplantation after Myocardial Infarction in Rats by Chapon, Catherine, Jackson, Johanna S., Aboagye, Eric O., Herlihy, Amy H., Jones, William A., Bhakoo, Kishore K.

“…Purpose The purpose of the study is to track iron-oxide nanoparticle-labelled adult rat bone marrow-derived stem cells (IO-rBMSCs) by magnetic resonance…”
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