Search Results - "Jackson, Brian C"

Update of human and mouse forkhead box (FOX) gene families by Jackson, Brian C, Carpenter, Christopher, Nebert, Daniel W, Vasiliou, Vasilis

“…The forkhead box (FOX) proteins are transcription factors that play complex and important roles in processes from development and organogenesis to regulation…”
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Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2 by Keysar, Stephen B, Le, Phuong N, Miller, Bettina, Jackson, Brian C, Eagles, Justin R, Nieto, Cera, Kim, Jihye, Tang, Binwu, Glogowska, Magdalena J, Morton, J Jason, Padilla-Just, Nuria, Gomez, Karina, Warnock, Emily, Reisinger, Julie, Arcaroli, John J, Messersmith, Wells A, Wakefield, Lalage M, Gao, Dexiang, Tan, Aik-Choon, Serracino, Hilary, Vasiliou, Vasilis, Roop, Dennis R, Wang, Xiao-Jing, Jimeno, Antonio

“…We have an incomplete understanding of the differences between cancer stem cells (CSCs) in human papillomavirus-positive (HPV-positive) and -negative…”
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Human ALDH1B1 Polymorphisms may Affect the Metabolism of Acetaldehyde and All-trans retinaldehyde—In Vitro Studies and Computational Modeling by Jackson, Brian C., Reigan, Philip, Miller, Bettina, Thompson, David C., Vasiliou, Vasilis

“…Purpose To elucidate additional substrate specificities of ALDH1B1 and determine the effect that human ALDH1B1 polymorphisms will have on substrate…”
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Update of human and mouse matrix metalloproteinase families by Jackson, Brian C, Nebert, Daniel W, Vasiliou, Vasilis

“…Matrix metalloproteinases (MMPs) are a family of zinc proteases that degrade most of the components of the extracellular matrix (ECM). MMPs also have a number…”
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Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily by Jackson, Brian C, Thompson, David C, Wright, Mathew W, McAndrews, Monica, Bernard, Alfred, Nebert, Daniel W, Vasiliou, Vasilis

“…The secretoglobins (SCGBs) comprise a family of small, secreted proteins found in animals exclusively of mammalian lineage. There are 11 human SCGB genes and…”
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Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress by Singh, Surendra, Brocker, Chad, Koppaka, Vindhya, Chen, Ying, Jackson, Brian C, Matsumoto, Akiko, Thompson, David C, Vasiliou, Vasilis

“…Reactive oxygen species (ROS) are continuously generated within living systems and the inability to manage ROS load leads to elevated oxidative stress and cell…”
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Aldehyde dehydrogenases in cellular responses to oxidative/electrophilicstress by Singh, Surendra, Brocker, Chad, Koppaka, Vindhya, Chen, Ying, Jackson, Brian C., Matsumoto, Akiko, Thompson, David C., Vasiliou, Vasilis

“…Reactive oxygen species (ROS) are continuously generated within living systems and the inability to manage ROS load leads to elevated oxidative stress and cell…”
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Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme by Stagos, Dimitrios, Chen, Ying, Brocker, Chad, Donald, Elizabeth, Jackson, Brian C, Orlicky, David J, Thompson, David C, Vasiliou, Vasilis

“…Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed…”
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Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions by Le, Phuong N., Keysar, Stephen B., Miller, Bettina, Eagles, Justin R., Chimed, Tugs‐Saikhan, Reisinger, Julie, Gomez, Karina E., Nieto, Cera, Jackson, Brian C., Somerset, Hilary L., Morton, John J., Wang, Xiao‐Jing, Jimeno, Antonio

“…Wnt pathway activation maintains the cancer stem cell (CSC) phenotype and promotes tumor progression, making it an attractive target for anti‐cancer therapy…”
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Update of the human and mouse SERPIN gene superfamily by Heit, Claire, Jackson, Brian C, McAndrews, Monica, Wright, Mathew W, Thompson, David C, Silverman, Gary A, Nebert, Daniel W, Vasiliou, Vasilis

“…The serpin family comprises a structurally similar, yet functionally diverse, set of proteins. Named originally for their function as serine proteinase…”
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Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma by Keysar, Stephen B, Gomes, Nathan, Miller, Bettina, Jackson, Brian C, Le, Phuong N, Morton, J Jason, Reisinger, Julie, Chimed, Tugs-Saikhan, Gomez, Karina E, Nieto, Cera, Frederick, Barbara, Pronk, Gijsbertus J, Somerset, Hilary L, Tan, Aik-Choon, Wang, Xiao-Jing, Raben, David, Su, Tin Tin, Jimeno, Antonio

“…Cancer stem cells (CSC) drive growth, therapy resistance, and recurrence in head and neck squamous cell carcinoma (HNSCC). Regulation of protein translation is…”
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Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression by Keysar, Stephen B, Eagles, Justin R, Miller, Bettina, Jackson, Brian C, Chowdhury, Farshad N, Reisinger, Julie, Chimed, Tugs-Saikhan, Le, Phuong N, Morton, John J, Somerset, Hilary L, Varella-Garcia, Marileila, Tan, Aik-Choon, Song, John I, Bowles, Daniel W, Reyland, Mary E, Jimeno, Antonio

“…Salivary gland cancers (SGC) frequently present with distant metastases many years after diagnosis, suggesting a cancer stem cell (CSC) subpopulation that…”
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Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology by Jackson, Brian C, Thompson, David C, Charkoftaki, Georgia, Vasiliou, Vasilis

“…Dead enzymes are gene products (proteins) that lack key residues required for catalytic activity. In the pre-genome era, dead enzymes were thought to occur…”
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ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein–protein interactions with HPRT1 by Vasiliou, Vasilis, Sandoval, Monica, Backos, Donald S., Jackson, Brian C., Chen, Ying, Reigan, Philip, Lanaspa, Miguel A., Johnson, Richard J., Koppaka, Vindhya, Thompson, David C.

“…Gout, a common form of inflammatory arthritis, is strongly associated with elevated uric acid concentrations in the blood (hyperuricemia). A recent study in…”
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Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2 by Jackson, Brian C., Holmes, Roger S., Backos, Donald S., Reigan, Philip, Thompson, David C., Vasiliou, Vasilis

“…Vertebrate ALDH2 genes encode mitochondrial enzymes capable of metabolizing acetaldehyde and other biological aldehydes in the body. Mammalian ALDH1B1, another…”
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Effects of Cutrine-Plus® algaecide and predators on wood frog (Lithobates sylvaticus) tadpole survival and growth by Christenson, Tia A., Horton, Marisa E., Jackson, Brian C., Smith, Geoffrey R., Rettig, Jessica E.

“…Copper contamination is increasing in many aquatic ecosystems. One mode by which copper can be introduced into aquatic ecosystems is as an algaecide, such as…”
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Impact of Duration Versus Frequency of Probing by Homalodisca vitripennis (Hemiptera: Cicadellidae) on Inoculation of Xylella fastidiosa by Jackson, Brian C., Blua, Matthew J., Bextine, Blake

“…Successful infection of the plant pathogenic bacterium Xylella fastidiosa (Wells) from an infected plant to a new host involves three main steps: 1)…”
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Update of the human and mouse SERPINgene superfamily by Heit, Claire, Jackson, Brian C, McAndrews, Monica, Wright, Mathew W, Thompson, David C, Silverman, Gary A, Nebert, Daniel W, Vasiliou, Vasilis

“…The serpin family comprises a structurally similar, yet functionally diverse, set of proteins. Named originally for their function as serine proteinase…”
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Homalodisca coagulata (Hemiptera: Cicadellidae) Feeding Posture by Bextine, Blake R, Jackson, Brian C, Harshman, David B, Miller, Thomas A

“…The sharpshooter Homalodisca coagulata Say (Hemiptera: Cicadellidae) is a polyphagous insect that feeds primarily from the xylem vessels of host plants. This…”
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Effects of Cutrine-Plus registered algaecide and predators on wood frog (Lithobates sylvaticus) tadpole survival and growth by Christenson, Tia A, Horton, Marisa E, Jackson, Brian C, Smith, Geoffrey R, Rettig, Jessica E

“…Copper contamination is increasing in many aquatic ecosystems. One mode by which copper can be introduced into aquatic ecosystems is as an algaecide, such as…”
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