Search Results - "Jackman, Nicole A"
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Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death
Published in ASN neuro (08-02-2012)“…Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain…”
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2
Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis
Published in Glia (01-09-2015)“…Astrocytes produce and export the antioxidant glutathione (GSH). Previously, we found that interleukin‐1β (IL‐1β) enhanced the expression of astrocyte system…”
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3
Interleukin-1[beta] protects astrocytes against oxidant-induced injury via an NF-[kappa]B-Dependent upregulation of glutathione synthesis
Published in Glia (01-09-2015)“…Astrocytes produce and export the antioxidant glutathione (GSH). Previously, we found that interleukin-1[beta] (IL-1[beta]) enhanced the expression of…”
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4
Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury
Published in Glia (15-11-2010)“…We recently demonstrated that interleukin-1β (IL-1β) increases system x(c)(-) (cystine/glutamate antiporter) activity in mixed cortical cell cultures,…”
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5
A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x Mediates Aglycemic Neuronal Cell Death
Published in ASN neuro (01-11-2015)“…The astrocyte cystine/glutamate antiporter (system x c − ) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation…”
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Journal Article -
6
Non-Cell Autonomous Influence of the Astrocyte System x on Hypoglycaemic Neuronal Cell Death
Published in ASN neuro (01-01-2012)“…Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain…”
Get full text
Journal Article -
7
A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc− Mediates Aglycemic Neuronal Cell Death
Published in ASN neuro (03-11-2015)“…The astrocyte cystine/glutamate antiporter (system xc−) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation…”
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Journal Article -
8
Generation of primary astrocyte cultures devoid of contaminating microglia
Published in Methods in molecular biology (Clifton, N.J.) (2012)“…Microglia, resident phagocytic cells of the central nervous system, are frequent contaminants of astrocyte cultures. Unfortunately and not always fully…”
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9
A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x c − Mediates Aglycemic Neuronal Cell Death
Published in ASN neuro (01-12-2015)“…The astrocyte cystine/glutamate antiporter (system x c − ) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation…”
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Journal Article -
10
Regulation of System x c − Activity and Expression in Astrocytes by Interleukin‐1β: Implications for Hypoxic Neuronal Injury
Published in Glia (15-11-2010)“…We recently demonstrated that interleukin‐1β (IL‐1β) increases system x c − (cystine/glutamate antiporter) activity in mixed cortical cell cultures, resulting…”
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Journal Article -
11
Regulation of System xc−Activity and Expression in Astrocytes by Interleukin-1β
Published in Glia (15-11-2010)“…We recently demonstrated that interleukin‐1β (IL‐1β) increases system xc− (cystine/glutamate antiporter) activity in mixed cortical cell cultures, resulting in…”
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Journal Article -
12
Regulation of system xc− activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury
Published in Glia (15-11-2010)“…We recently demonstrated that interleukin-1β (IL-1β) increases system x c − (cystine/glutamate antiporter) activity in mixed cortical cell cultures, resulting…”
Get full text
Journal Article -
13
Non-Cell Autonomous Influence of the Astrocyte System x c − on Hypoglycaemic Neuronal Cell Death
Published in ASN neuro (01-01-2012)“…Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain…”
Get full text
Journal Article