Search Results - "Jack L. Martin"

B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury by Inaba, Akimichi, Tuong, Zewen K, Riding, Alexandra M, Mathews, Rebeccah J, Martin, Jack L, Saeb-Parsy, Kourosh, Clatworthy, Menna R

“…Acute kidney injury (AKI) is a serious condition affecting one fifth of hospital inpatients. B lymphocytes have immunological functions beyond Ab production…”
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Validation of Reference Genes for Oral Cancer Detection Panels in a Prospective Blinded Cohort by Martin, Jack L

“…Reference genes are needed as internal controls to determine relative expression for clinical application of gene expression panels. Candidate constitutively…”
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Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury by Beach, Timothy E., Prag, Hiran A., Pala, Laura, Logan, Angela, Huang, Margaret M., Gruszczyk, Anja V., Martin, Jack L., Mahbubani, Krishnaa, Hamed, Mazin O., Hosgood, Sarah A., Nicholson, Michael L., James, Andrew M., Hartley, Richard C., Murphy, Michael P., Saeb-Parsy, Kourosh

“…Renal ischemia reperfusion (IR) injury leads to significant patient morbidity and mortality, and its amelioration is an urgent unmet clinical need. Succinate…”
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Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA by Arndt, Sabine, Baeza-Garza, Carlos D., Logan, Angela, Rosa, Tiziana, Wedmann, Rudolf, Prime, Tracy A., Martin, Jack L., Saeb-Parsy, Kourosh, Krieg, Thomas, Filipovic, Milos R., Hartley, Richard C., Murphy, Michael P.

“…Hydrogen sulfide (H2S) is produced endogenously in vivo and has multiple effects on signaling pathways and cell function. Mitochondria can be both an H2S…”
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Acute and Late Outcomes of Unprotected Left Main Stenting in Comparison With Surgical Revascularization by Buszman, Pawel E., MD, FACC, Kiesz, Stefan R., MD, FACC, Bochenek, Andrzej, MD, Peszek-Przybyla, Ewa, MD, Szkrobka, Iwona, MD, Debinski, Marcin, MD, Bialkowska, Bozena, MD, Dudek, Dariusz, MD, Gruszka, Agata, MD, Zurakowski, Aleksander, MD, Milewski, Krzysztof, MD, Wilczynski, Miroslaw, MD, Rzeszutko, Lukasz, MD, Buszman, Piotr, Szymszal, Jan, PhD, Martin, Jack L., MD, FACC, Tendera, Michal, MD, FACC

“…Acute and Late Outcomes of Unprotected Left Main Stenting in Comparison With Surgical Revascularization Pawel E. Buszman, Stefan R. Kiesz, Andrzej Bochenek,…”
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A randomized trial comparing compression, perclose proglide™ and Angio-Seal VIP™ for arterial closure following percutaneous coronary intervention: The cap trial by Martin, Jack L., Pratsos, Antonis, Magargee, Edward, Mayhew, Kim, Pensyl, Catherine, Nunn, Mary, Day, Francis, Shapiro, Timothy

“…Objective: This prospective randomized trial compared the Angio‐Seal VIP™ with Perclose Proglide™ and to manual compression with respect to time to hemostasis…”
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Predictors of Infarct Size After Primary Coronary Angioplasty in Acute Myocardial Infarction from Pooled Analysis from Four Contemporary Trials by Stone, Gregg W., MD, Dixon, Simon R., MD, Grines, Cindy L., MD, Cox, David A., MD, Webb, John G., MD, Brodie, Bruce R., MD, Griffin, John J., MD, Martin, Jack L., MD, Fahy, Martin, MsC, Mehran, Roxana, MD, Miller, Todd D., MD, Gibbons, Raymond J., MD, O’Neill, William W., MD

“…Determinates of infarct size in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) have been incompletely…”
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Diabetes-induced oxidative stress and low-grade inflammation in porcine coronary arteries by Zhang, LiFeng, Zalewski, Andrew, Liu, Yuchuan, Mazurek, Tomasz, Cowan, Scott, Martin, Jack L, Hofmann, Susanna M, Vlassara, Helen, Shi, Yi

“…Multiple pathways contribute to accelerated coronary atherosclerosis in diabetics, including increased oxidative stress and inflammatory burden. Accordingly,…”
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Effect of Supersaturated Oxygen Delivery on Infarct Size After Percutaneous Coronary Intervention in Acute Myocardial Infarction by Stone, Gregg W, Martin, Jack L, de Boer, Menko-Jan, Margheri, Massimo, Bramucci, Ezio, Blankenship, James C, Metzger, D Christopher, Gibbons, Raymond J, Lindsay, Barbara S, Weiner, Bonnie H, Lansky, Alexandra J, Krucoff, Mitchell W, Fahy, Martin, Boscardin, W John

“…BACKGROUND—Myocardial salvage is often suboptimal after percutaneous coronary intervention in ST-segment elevation myocardial infarction. Posthoc subgroup…”
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Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation by Martin, Jack L., Costa, Ana S. H., Gruszczyk, Anja V., Beach, Timothy E., Allen, Fay M., Prag, Hiran A., Hinchy, Elizabeth C., Mahbubani, Krishnaa, Hamed, Mazin, Tronci, Laura, Nikitopoulou, Efterpi, James, Andrew M., Krieg, Thomas, Robinson, Alan J., Huang, Margaret M., Caldwell, Stuart T., Logan, Angela, Pala, Laura, Hartley, Richard C., Frezza, Christian, Saeb-Parsy, Kourosh, Murphy, Michael P.

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Mitochondria as Therapeutic Targets in Transplantation by Saeb-Parsy, Kourosh, Martin, Jack L., Summers, Dominic M., Watson, Christopher J.E., Krieg, Thomas, Murphy, Michael P.

“…Advances in surgical procedures, technology, and immune suppression have transformed organ transplantation. However, the metabolic changes that occur during…”
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Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury by Martin, Jack L., Gruszczyk, Anja V., Beach, Timothy E., Murphy, Michael P., Saeb-Parsy, Kourosh

“…Acute kidney injury (AKI) remains a major problem in critically unwell children and young adults. Ischaemia reperfusion (IR) injury is a major contributor to…”
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An emerging role for stress granules in neurodegenerative disease and hearing loss by Martin, Jack L., Dawson, Sally J., Gale, Jonathan E.

“…•Evidence is accumulating to show that stress granules are essential for the maintenance of cochlear function and determining its response to stress.•Stress…”
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The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition by Martin, Jack L, Terry, Stephen J, Gale, Jonathan E, Dawson, Sally J

“…Cisplatin is an effective platinum-based chemotherapeutic with several side effects, including ototoxicity. Cochlear cells have low rates of proliferation yet…”
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Left Main Stenting in Comparison With Surgical Revascularization: 10-Year Outcomes of the (Left Main Coronary Artery Stenting) LE MANS Trial by Buszman, Pawel E, Buszman, Piotr P, Banasiewicz-Szkróbka, Iwona, Milewski, Krzysztof P, Żurakowski, Aleksander, Orlik, Bartłomiej, Konkolewska, Magda, Trela, Błażej, Janas, Adam, Martin, Jack L, Kiesz, R Stefan, Bochenek, Andrzej

“…This study has reported 10-year clinical follow-up of patients enrolled in the prospective, randomized LE MANS (Left Main Stenting) trial. The very long-term…”
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Localized Liver Injury During Normothermic Ex Situ Liver Perfusion Has No Impact on Short-term Liver Transplant Outcomes by Martin, Jack L, Rhodes, Freya, Upponi, Sara, Udeaja, Yagazie, Swift, Lisa, Fear, Corina, Webster, Rachel, Webb, Gwilym James, Allison, Michael, Paterson, Anna, Gaurav, Rohit, Butler, Andrew J, Watson, Christopher J E

“…Normothermic ex situ liver perfusion (NESLiP) has the potential to increase organ utilization. Radiological evidence of localized liver injury due to…”
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Correction to: Mitochondria as Therapeutic Targets in Transplantation: (Trends in Molecular Medicine 27:2 p:185–198, 2021) by Saeb-Parsy, Kourosh, Martin, Jack L., Summers, Dominic M., Watson, Christopher J.E., Krieg, Thomas, Murphy, Michael P.

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Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation by Martin, Jack L., Costa, Ana S. H., Gruszczyk, Anja V., Beach, Timothy E., Allen, Fay M., Prag, Hiran A., Hinchy, Elizabeth C., Mahbubani, Krishnaa, Hamed, Mazin, Tronci, Laura, Nikitopoulou, Efterpi, James, Andrew M., Krieg, Thomas, Robinson, Alan J., Huang, Margaret M., Caldwell, Stuart T., Logan, Angela, Pala, Laura, Hartley, Richard C., Frezza, Christian, Saeb-Parsy, Kourosh, Murphy, Michael P.

“…During heart transplantation, storage in cold preservation solution is thought to protect the organ by slowing metabolism, providing osmotic support and…”
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ST-Elevation Myocardial Infarction Track by Abella, Benjamin S, Otterspoor, Luuk, Nichol, Graham, Martin, Jack L

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Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel -Eluting or a Bare-Metal Stent Into a Single Coronary Artery by Martin, Jack L., MD, Ellis, Stephen G., MD, Colombo, Antonio, MD, Grube, Eberhard, MD, Maloney, Tom, MS, Friedman, Mark I., MD, Baim, Donald S., MD, Dawkins, Keith, MD, Caputo, Ron, MD, Stone, Gregg W., MD

“…Limited data are available on the relative effect of drug-eluting versus bare-metal stents on the requirement for subsequent coronary artery bypass grafting…”
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