Search Results - "Jack, Sandy"

Neo-train: study protocol and feasibility results for a two-arm randomized controlled trial investigating the effect of supervised exercise during neoadjuvant chemotherapy on tumour response in patients with breast cancer by Kjeldsted, Eva, Ammitzball, Gunn, Jargensen, Lars Bo, Lodin, Alexey, Bojesen, Rasmus Dahlin, Ceballos, Silvia Gonzalez, Rosthaj, Susanne, Laenkholm, Anne-Vibeke, Skou, Saren T, Jack, Sandy, Gehl, Julie, Dalton, Susanne Oksbjerg

“…Abstract Background Prehabilitation with exercise interventions during neoadjuvant chemotherapy (NACT) is effective in reducing physical and psychosocial…”
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Systematic review of evidence for relationships between physiological and CT indices of small airways and clinical outcomes in COPD by Gove, Kerry, Wilkinson, Tom, Jack, Sandy, Ostridge, Kristoffer, Thompson, Bruce, Conway, Joy

“…Small airways disease (SAD) is considered pivotal in the pathology of COPD. There are numerous publications describing physiological and Computed Tomography…”
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Frail2Fit study protocol: a feasibility and acceptability study of a virtual multimodal intervention delivered by volunteers to improve functional outcomes in older adults with frailty after discharge from hospital by Meredith, Samantha Jane, Roberts, Helen, Grocott, Michael P W, Jack, Sandy, Murphy, Jane, Varkonyi-Sepp, Judit, Bates, Andrew, Lim, Stephen Eu Ruen

“…IntroductionPhysical activity (PA) and replete nutritional status are key to maintaining independence and improving frailty status among frail older adults. In…”
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Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery by West, Malcolm A., Dijk, David P.J., Gleadowe, Fredrick, Reeves, Thomas, Primrose, John N., Abu Hilal, Mohammed, Edwards, Mark R., Jack, Sandy, Rensen, Sander S.S., Grocott, Michael P.W., Levett, Denny Z.H., Olde Damink, Steven W.M.

“…Background Body composition assessment, measured using single‐slice computed tomography (CT) image at L3 level, and aerobic physical fitness, objectively…”
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SafeFit Trial: virtual clinics to deliver a multimodal intervention to improve psychological and physical well-being in people with cancer. Protocol of a COVID-19 targeted non-randomised phase III trial by Grimmett, Chloe, Bates, Andrew, West, Malcolm, Leggett, Samantha, Varkonyi-Sepp, Judit, Campbell, Anna, Davis, June, Wootton, Stephen, Shaw, Clare, Barlow, Rachael, Ashcroft, Joanna, Scott, Andrew, Moyes, Helen, Hawkins, Lesley, Levett, Denny Z H, Williams, Fran, Grocott, Michael P W, Jack, Sandy

“…IntroductionThe impact of the COVID-19 pandemic (caused by the SARS-CoV-2 virus) on individuals with cancer has been profound. It has led to increased anxiety,…”
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Multiphasic Prehabilitation Across the Cancer Continuum: A Narrative Review and Conceptual Framework by Santa Mina, Daniel, van Rooijen, Stefanus J, Minnella, Enrico M, Alibhai, Shabbir M H, Brahmbhatt, Priya, Dalton, Susanne O, Gillis, Chelsia, Grocott, Michael P W, Howell, Doris, Randall, Ian M, Sabiston, Catherine M, Silver, Julie K, Slooter, Gerrit, West, Malcolm, Jack, Sandy, Carli, Franco

“…The field of cancer survivorship has significantly advanced person-centered care throughout the cancer continuum. Within cancer survivorship, the last decade…”
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Cardiopulmonary exercise testing has greater prognostic value than sarcopenia in oesophago‐gastric cancer patients undergoing neoadjuvant therapy and surgical resection by West, Malcolm A, Baker, William CA, Rahman, Saqib, Munro, Alicia, Jack, Sandy, Grocott, Michael PW, Underwood, Timothy J, Levett, Denny ZH

“…Background Sarcopenia (low skeletal muscle mass), myosteatosis (low skeletal muscle radiation‐attenuation) and fitness are independently associated with…”
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Preparing for and Not Waiting for Surgery by Bates, Andrew, West, Malcolm A, Jack, Sandy, Grocott, Michael P W

“…Cancer surgery is an essential treatment strategy but can disrupt patients' physical and psychological health. With worldwide demand for surgery expected to…”
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The effects of exercise on pain, fatigue, insomnia, and health perceptions in patients with operable advanced stage rectal cancer prior to surgery: a pilot trial by Brunet, Jennifer, Burke, Shaunna, Grocott, Michael P W, West, Malcolm A, Jack, Sandy

“…Promoting quality of life (QoL) is a key priority in cancer care. We investigated the hypothesis that, in comparison to usual care, exercise post-neoadjuvant…”
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The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer patients--an observational pilot study by West, Malcolm A, Loughney, Lisa, Lythgoe, Daniel, Barben, Christopher P, Adams, Valerie L, Bimson, William E, Grocott, Michael P W, Jack, Sandy, Kemp, Graham J

“…In the United Kingdom, patients with locally advanced rectal cancer routinely receive neoadjuvant chemoradiotherapy. However, the effects of this on physical…”
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Exercise-Induced Systemic Venous Hypertension in the Fontan Circulation by Navaratnam, Devaraj, BMedSci, Fitzsimmons, Samantha, MBChB, Grocott, Michael, MBBS, Rossiter, Harry B., PhD, Emmanuel, Yaso, PhD, MBBS, Diller, Gerard-Paul, MD, PhD, Gordon-Walker, Timothy, PhD, MBBS, Jack, Sandy, PhD, Sheron, Nick, MD, MBBS, Pappachan, John, MB BChir, Pratap, Jayant Nick, MB BChir, Vettukattil, Joseph J., MD, Veldtman, Gruschen, MBChB

“…Increasingly end-organ injury is being demonstrated late after institution of the Fontan circulation, particularly liver fibrosis and cirrhosis. The exact…”
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The effects of neoadjuvant chemoradiotherapy and an in-hospital exercise training programme on physical fitness and quality of life in locally advanced rectal cancer patients: a randomised controlled trial (The EMPOWER Trial) by Loughney, Lisa, West, Malcolm A, Moyses, Helen, Bates, Andrew, Kemp, Graham J, Hawkins, Lesley, Varkonyi-Sepp, Judit, Burke, Shaunna, Barben, Christopher P, Calverley, Peter M, Cox, Trevor, Palmer, Daniel H, Mythen, Michael G, Grocott, Michael P W, Jack, Sandy

“…The EMPOWER trial aimed to assess the effects of a 9-week exercise prehabilitation programme on physical fitness compared with a usual care control group…”
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Establishment of clinical exercise physiology as a regulated healthcare profession in the UK: a progress report by Jones, Helen, Crozier, Anthony, George, Keith, Miller, Gemma, Whyte, Greg P, Rycroft, Joanna, Scott, Andrew, Buckley, John P, McGregor, Gordon, Askew, Christopher David, Jack, Sandy, Birkett, Steffan, Broom, David R, Tolfrey, Keith, Campbell, Anna, Skelton, Dawn A, Steenkamp, Lizanne, Savage, Jude, Green, Daniel J

“…In 2021, a ‘call to action’ was published to highlight the need for professional regulation of clinical exercise physiologists to be established within UK…”
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The Wessex Fit-4-Cancer Surgery Trial (WesFit): a protocol for a factorial-design, pragmatic randomised-controlled trial investigating the effects of a multi-modal prehabilitation programme in patients undergoing elective major intra-cavity cancer surgery [version 2; peer review: 2 approved] by West, Malcolm, Bates, Andrew, Grimmett, Chloe, Allen, Cait, Green, Richard, Hawkins, Lesley, Moyses, Helen, Leggett, Samantha, Z H Levett, Denny, Rickard, Sally, Varkonyi-Sepp, Judit, Williams, Fran, Wootton, Stephen, Hayes, Matthew, P W Grocott, Micheal, Jack, Sandy

“…Background: Surgical resection remains the primary curative treatment for intra-cavity cancer. Low physical fitness and psychological factors such as…”
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Body composition and chemotherapy toxicity in women with early breast cancer (CANDO-3): protocol for an observational cohort study by Durkin, Kesta, Heetun, Adam, Ewings, Sean, Munday, Richard, Wootton, Stephen A, Turner, Lesley, Copson, Ellen R, Cutress, Ramsey I, Batchelor, James, Copson, Ellen R, Cutress, Ramsey I, Durkin, Kesta, Ewings, Sean, Grocott, Mike, Harvie, Michelle, Heetun, Adam, Jack, Sandy, Jackson, Alan, James, Fiona, Munday, Richard, Turner, Lesley, Wootton, Stephen

“…IntroductionSystemic anticancer therapy is given to selected patients with early breast cancer (EBC) before or after surgery with the aim of eradicating…”
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Individualised Exercise Training Enhances Antioxidant Buffering Capacity in Idiopathic Pulmonary Fibrosis by Wallis, Tim J. M., Minnion, Magdalena, Freeman, Anna, Bates, Andrew, Otto, James M., Wootton, Stephen A., Fletcher, Sophie V., Grocott, Michael P. W., Feelisch, Martin, Jones, Mark G., Jack, Sandy

“…Exercise training is recommended for patients with idiopathic pulmonary fibrosis (IPF); however, the mechanism(s) underlying its physiological benefits remain…”
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Exercise Training Induces a Shift in Extracellular Redox Status with Alterations in the Pulmonary and Systemic Redox Landscape in Asthma by Freeman, Anna, Cellura, Doriana, Minnion, Magdalena, Fernandez, Bernadette O, Spalluto, Cosma Mirella, Levett, Denny, Bates, Andrew, Wallis, Timothy, Watson, Alastair, Jack, Sandy, Staples, Karl J, Grocott, Michael P W, Feelisch, Martin, Wilkinson, Tom M A

“…Redox dysregulation and oxidative stress have been implicated in asthma pathogenesis. Exercise interventions improve symptoms and reduce inflammation in asthma…”
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Physical activity levels in locally advanced rectal cancer patients following neoadjuvant chemoradiotherapy and an exercise training programme before surgery: a pilot study by Loughney, Lisa, West, Malcolm A, Dimitrov, Borislav D, Kemp, Graham J, Grocott, Michael Pw, Jack, Sandy

“…The aim of this pilot study was to measure changes in physical activity level (PAL) variables, as well as sleep duration and efficiency in people with locally…”
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The effects of cancer therapies on physical fitness before oesophagogastric cancer surgery: a prospective, blinded, multi-centre, observational, cohort study [version 1; peer review: 2 approved] by West, Malcolm A, Anastasiou, Zachos, Ambler, Gareth, Loughney, Lisa, Mythen, Michael G, Owen, Thomas, Danjoux, Gerard, Levett, Denny Z H, Calverley, Peter M A, Kelly, Jamie J, Jack, Sandy, Grocott, Michael P W

“…Neoadjuvant cancer treatment is associated with improved survival following major oesophagogastric cancer surgery. The impact of neoadjuvant…”
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Ventilatory Responses to Inhaled Carbon Dioxide, Hypoxia, and Exercise in Idiopathic Hyperventilation by Jack, Sandy, Rossiter, Harry B, Pearson, Michael G, Ward, Susan A, Warburton, Christopher J, Whipp, Brian J

“…Idiopathic hyperventilation (IH) is a poorly understood condition of sustained hypocapnia and controversial etiology. Although behavioral/emotional factors may…”
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