Search Results - "Jack, Richard M"
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Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease
Published in JCI insight (08-12-2016)“…Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating…”
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Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease
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Complement Receptor Type 1 (CR1, CD35) Is a Receptor for C1q
Published in Immunity (Cambridge, Mass.) (01-09-1997)“…Molecular definition of the cellular receptor for the collagen domain of C1q has been elusive. We now report that C1q binds specifically to human CR1 (CD35),…”
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Low Erythrocyte Complement Receptor Type 1 (CR1, CD35) Expression in Preeclamptic Gestations
Published in American journal of reproductive immunology (1989) (01-12-2005)“…Problem Erythrocyte complement receptor type 1 (E‐CR1) is the main immune complex clearance mechanism in humans. Decreased E‐CR1 expression is noted in certain…”
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The Role of Complement Component C3b and Its Receptors in Sperm-Oocyte Interaction
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1993)“…Previous studies have shown that human sperm that have undergone the acrosome reaction express a unique tissue-specific variant of the complement component 3…”
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A path from primary protein sequence to ligand recognition
Published in Proteins, structure, function, and bioinformatics (01-03-2003)“…A novel method to organize protein structural information based solely on sequence is presented. The method clusters proteins into families that correlate with…”
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Genome-Wide Profile of Oxidoreductases in Viruses, Prokaryotes, and Eukaryotes
Published in Journal of proteome research (01-11-2003)“…Enzymes that utilize nicotinamide adenine dinucleotide (NAD) or its 2‘-phosphate derivative (NADP) are found throughout the kingdoms of life. These enzymes are…”
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Biostability and pharmacokinetics of LJP 920, an octameric Gal (α1-3) Gal conjugate for the inhibition of xenotransplantation rejection
Published in Journal of pharmacy and pharmacology (01-07-2001)“…Antibodies to an α‐galactosyl saccharide structure present in human serum are associated with hyperacute rejection and delayed xenograft rejection after…”
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Triad Therapeutics: integration of NMR structural determinations and smart chemistry to speed drug discovery
Published in Drug discovery today (01-03-2002)“…Triad Therapeutics’ proprietary technologies enable dramatic increases in both the speed of lead compound generation and the quality (binding affinity and…”
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Fetal origin of amniotic fluid polymorphonuclear leukocytes
Published in American journal of obstetrics and gynecology (01-01-1997)“…OBJECTIVE: Although polymorphonuclear leukocytes are the inflammatory cells most frequently recovered from the amniotic cavity in cases of suspected…”
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Characterization of the effector cell that mediates cytotoxicity against Theileria parva (East Coast fever) in immune cattle
Published in Infection and Immunity (01-06-1981)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Purification of human lung leukotriene C4 synthase and preparation of a polyclonal antibody
Published in American journal of respiratory and critical care medicine (01-07-1995)“…Leukotriene (LT) C4 synthase is an integral membrane protein that catalyzes the conjugation of LTA4 to reduced glutathione to form LTC4. LTC4 synthase has been…”
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ORIGINAL ARTICLE: Low Erythrocyte Complement Receptor Type 1 (CR1, CD35) Expression in Preeclamptic Gestations
Published in American Journal Of Reproductive Immunology (01-12-2005)“…Problem: Erythrocyte complement receptor type 1 (E-CR1) is the main immune complex clearance mechanism in humans. Decreased E-CR1 expression is noted in…”
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DEVELOPMENT OF MULTIVALENT TOLERAGENS TO INHIBIT BINDING OF HUMAN ANTI-GALACTOSE??1,3 GALACTOSE ANTIBODIES
Published in Transplantation (01-05-1999)Get full text
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Purification of human leukotriene C4 synthase
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1992)“…Leukotriene (LT) C4 synthase, the enzyme that catalyzes the conjugation of LTA4 with reduced glutathione to form LTC4, was purified to homogeneity from the…”
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Regulation of C1q receptor expression on human polymorphonuclear leukocytes
Published in The Journal of immunology (1950) (01-07-1994)“…The C1q receptor (C1qR) is expressed on a variety of cells, including polymorphonuclear leukocytes (PMN), in which stimulation by the C1qR leads to activation…”
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Granulocyte-macrophage colony-stimulating factor increases synthesis and expression of CR1 and CR3 by human peripheral blood neutrophils
Published in The Journal of immunology (1950) (15-11-1990)“…Polymorphonuclear leukocytes (PMN) constitutively synthesize various plasma membrane proteins including CR1(3) (CD35), CR3 (or Mac-1) alpha-chain (CD11b) and…”
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Lipid and membrane protein transfer from human neutrophils to schistosomes is mediated by ligand binding
Published in Journal of cell science (01-10-1993)“…Attachment of human neutrophils to schistosomula of Schistosoma mansoni involves leukocyte receptors recognizing carbohydrate, complement and/or IgG ligands on…”
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Abnormal Stimulated Adherence of Neonatal Granulocytes: Impaired Induction of Surface MAC-1 by Chemotactic Factors or Secretagogues
Published in Blood (01-09-1987)“…To identify possible secretory determinants of impaired hyperadherence and stimulated migration of neonatal granulocytes (NGs), we performed correlative…”
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