Search Results - "Jablonski, Angela M."
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Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology
Published in Neurobiology of disease (01-12-2021)“…TDP-43 pathology is a hallmark of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal lobar degeneration (FTLD). Namely, both diseases feature aggregated…”
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Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription
Published in PLoS biology (01-04-2015)“…Protein quality control is essential for clearing misfolded and aggregated proteins from the cell, and its failure is associated with many neurodegenerative…”
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Oxygen sensing neurons and neuropeptides regulate survival after anoxia in developing C. elegans
Published in PloS one (26-06-2014)“…Hypoxic brain injury remains a major source of neurodevelopmental impairment for both term and preterm infants. The perinatal period is a time of rapid…”
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GluA1 promotes the activity-dependent development of motor circuitry in the developing segmental spinal cord
Published in Annals of the New York Academy of Sciences (01-03-2013)“…The neuronal dendritic tree is a key determinant of how neurons receive, compute, and transmit information. During early postnatal life, synaptic activity…”
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Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance
Published in The Journal of neuroscience (21-10-2015)“…Misfolded proteins accumulate and aggregate in neurodegenerative disease. The existence of these deposits reflects a derangement in the protein homeostasis…”
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Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription: e1002114
Published in PLoS biology (01-04-2015)“…Protein quality control is essential for clearing misfolded and aggregated proteins from the cell, and its failure is associated with many neurodegenerative…”
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Journal Article