Search Results - "Jablonska, Patrycja"
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Macrophage-Derived Adenosine Deaminase 2 Correlates with M2 Macrophage Phenotype in Triple Negative Breast Cancer
Published in International journal of molecular sciences (05-04-2021)“…Several lines of evidence suggest that altered adenosine deaminase (ADA) activity, especially its ADA2 iso-enzyme, is associated with malignant breast cancer…”
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2
Elevated Plasma Concentration of 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR) Highlights Malignancy of Renal Cell Carcinoma
Published in International journal of molecular sciences (01-02-2024)“…Nicotinamide (NA) derivatives play crucial roles in various biological processes, such as inflammation, regulation of the cell cycle, and DNA repair. Recently,…”
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3
Enhanced Muscle Strength in Dyslipidemic Mice and Its Relation to Increased Capacity for Fatty Acid Oxidation
Published in International journal of molecular sciences (12-11-2021)“…Dyslipidemia is commonly linked to skeletal muscle dysfunction, accumulation of intramyocellular lipids, and insulin resistance. However, our previous research…”
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An unusual nicotinamide derivative, 4-pyridone-3-carboxamide ribonucleoside (4PYR), is a novel endothelial toxin and oncometabolite
Published in Experimental & molecular medicine (01-09-2021)“…Our recent studies identified a novel pathway of nicotinamide metabolism that involves 4-pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR) and demonstrated…”
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5
Nucleotide ecto-enzyme metabolic pattern and spatial distribution in calcific aortic valve disease; its relation to pathological changes and clinical presentation
Published in Clinical research in cardiology (01-02-2020)“…Background Extracellular nucleotide metabolism contributes to chronic inflammation, cell differentiation, and tissue mineralization by controlling nucleotide…”
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6
Rosiglitazone Ameliorates Cardiac and Skeletal Muscle Dysfunction by Correction of Energetics in Huntington’s Disease
Published in Cells (Basel, Switzerland) (27-08-2022)“…Huntington’s disease (HD) is a rare neurodegenerative disease that is accompanied by skeletal muscle atrophy and cardiomyopathy. Tissues affected by HD…”
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Differences in Extracellular NAD + and NMN Metabolism on the Surface of Vascular Endothelial Cells
Published in Biology (Basel, Switzerland) (27-04-2022)“…The disruption of the metabolism of extracellular NAD and NMN may affect related signaling cascades and pathologies, such as cardiovascular or respiratory…”
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Systemic Effects of Radiotherapy and Concurrent Chemo-Radiotherapy in Head and Neck Cancer Patients-Comparison of Serum Metabolome Profiles
Published in Metabolites (07-02-2020)“…Anticancer treatment induces systemic molecular changes that could be detected at the level of biofluids. Understanding how human metabolism is influenced by…”
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The Effect of One Anastomosis Gastric Bypass on Branched-Chain Fatty Acid and Branched-Chain Amino Acid Metabolism in Subjects with Morbid Obesity
Published in Obesity surgery (2020)“…Background Subjects with morbid obesity have low levels of serum branched-chain fatty acids (BCFAs), which correlate inversely with insulin resistance,…”
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10
Developing application in JavaScript - comparison of commercial and open source solution
Published in Journal of Computer Sciences Institute (30-09-2018)“…Subject of this article is comparative analysis of two popular frameworks in JavaScript: AngularJS (open source) and Ext JS (commercial package). There were…”
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11
Serum fatty acid profiles in breast cancer patients following treatment
Published in BMC cancer (12-05-2023)“…Breast cancer is associated with alterations in lipid metabolism. The treatment of breast cancer can also affect serum lipid composition. The purpose of this…”
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12
Quirky n-words in Polish: NPIs, Negative Qantifiers or neither?
Published in Nordlyd (Tromsø, Norway) (27-01-2004)“…The present paper investigates the contexts in which the so-called n-words - the items which are taken to be Negative Polarity Items in Slavic languages -…”
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Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis
Published in Journal of Chromatography A (29-09-2017)“…•A new LC/MS method was developed for analysis of amino acid-related (AA) metabolome.•The method was applied for analysis of plasma in calcific aortic stenosis…”
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14
The comparison of nucleotide metabolites and amino acids patterns in patients with eating disorders, with and without symptoms of depression
Published in Nucleosides, nucleotides & nucleic acids (2022)“…Purines, pyrimidines, and amino acid level have gained attention recently as potential determinants of mental disorders. However, eating disorders patients…”
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Simultaneous accurate quantification of HO-1, CD39, and CD73 in human calcified aortic valves using multiple enzyme digestion – filter aided sample pretreatment (MED-FASP) method and targeted proteomics
Published in Talanta (Oxford) (15-05-2018)“…Several proteins such as membrane-associated ectonucleotidases: ecto-5’-nucleotidase (E5NT/CD73) and ectonucleoside triphosphate diphosphohydrolase 1…”
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Comparison of plasma nucleotide metabolites and amino acids pattern in patients with binge eating disorder and obesity
Published in Nucleosides, nucleotides & nucleic acids (01-01-2021)“…Binge eating disorder (BED) increasingly affects population, but the mechanisms of the disease and its biomarkers are not well characterized. Recently, plasma…”
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Increased activity of vascular adenosine deaminase in atherosclerosis and therapeutic potential of its inhibition
Published in Cardiovascular research (01-11-2016)“…Extracellular nucleotides and adenosine that are formed or degraded by membrane-bound ecto-enzymes could affect atherosclerosis by regulating the inflammation…”
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The new insight into extracellular NAD + degradation-the contribution of CD38 and CD73 in calcific aortic valve disease
Published in Journal of cellular and molecular medicine (01-07-2021)“…Nicotinamide adenine dinucleotide (NAD ) is crucial for cell energy metabolism and many signalling processes. Recently, we proved the role of ecto-enzymes in…”
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19
Inhibition of LPS-stimulated ecto-adenosine deaminase attenuates endothelial cell activation
Published in Journal of molecular and cellular cardiology (01-03-2019)“…Vascular inflammation is an important factor in the pathophysiology of cardiovascular diseases, such as atherosclerosis. Changes in the extracellular…”
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Statin treatment of patients with calcific aortic valve disease modulates extracellular adenosine metabolism on the cell surface of the aortic valve
Published in Nucleosides, nucleotides & nucleic acids (01-12-2020)“…Statins efficiently prevent cardiovascular events by lipid-dependent and independent mechanisms. We hypothesize that part of these protective effects could be…”
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