Search Results - "Jabba, Sairam V"
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Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti‐inflammatory effects of eucalyptol
Published in British journal of pharmacology (01-05-2017)“…Background and Purpose Eucalyptol (1,8‐cineol), the major ingredient in the essential oil of eucalyptus leaves and other medicinal plants, has long been known…”
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Antillatoxin-Stimulated Neurite Outgrowth Involves the Brain-Derived Neurotrophic Factor (BDNF) - Tropomyosin Related Kinase B (TrkB) Signaling Pathway
Published in Journal of natural products (Washington, D.C.) (25-03-2022)“…Voltage-gated sodium channel (VGSC) activators promote neurite outgrowth by augmenting intracellular Na+ concentration ([Na+]i) and upregulating…”
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3
Biosynthetically Intriguing Chlorinated Lipophilic Metabolites from Geographically Distant Tropical Marine Cyanobacteria
Published in Journal of organic chemistry (04-05-2012)“…Five new vinylchlorine-containing metabolites, the lipoamides janthielamide A and kimbeamides A–C and the ketide-extended pyranone kimbelactone A, have been…”
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4
Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model
Published in BMC medicine (20-08-2004)“…Pendred syndrome, a common autosomal-recessive disorder characterized by congenital deafness and goiter, is caused by mutations of SLC26A4, which codes for…”
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5
Formation of flavorant-propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids
Published in Nicotine & tobacco research (19-08-2019)“…"Vaping" electronic cigarettes (e-cigarettes) is increasingly popular with youth, driven by the wide range of available flavors, often created using flavor…”
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6
Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways
Published in Cell host & microbe (10-02-2021)“…The intestinal epithelium senses nutritional and microbial stimuli using epithelial sensory enteroendocrine cells (EEC). EECs communicate nutritional…”
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Turbocharged Juul device challenges European tobacco regulators
Published in The European respiratory journal (01-08-2020)Get full text
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Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model
Published in BMC medicine (22-12-2006)“…Pendred syndrome, an autosomal-recessive disorder characterized by deafness and goiter, is caused by a mutation of SLC26A4, which codes for the anion exchanger…”
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9
Estimating Fluid Consumption Volumes in Electronic Cigarette Use-Reply
Published in JAMA internal medicine (01-03-2020)Get more information
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10
Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues
Published in JAMA : the journal of the American Medical Association (03-09-2024)“…This study characterizes and quantifies constituents in 2 e-cigarette products to assess product consistency and inform future risk assessments…”
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Synthetic Cooling Agent and Other Flavor Additives in “Non-Menthol” Cigarettes Marketed in California and Massachusetts After Menthol Cigarette Bans
Published in JAMA : the journal of the American Medical Association (07-11-2023)“…This study uses a bioassay and chemical analysis to determine the proportion of newly introduced “non-menthol” cigarette brands with sensory cooling effects,…”
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Synthetic Cooling Agents in US-marketed E-cigarette Refill Liquids and Popular Disposable E-cigarettes: Chemical Analysis and Risk Assessment
Published in Nicotine & tobacco research (15-06-2022)“…Abstract Introduction Menthol, through its cooling and pleasant sensory effects, facilitates smoking and tobacco product initiation, resulting in the high…”
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13
Microarray-based comparison of three amplification methods for nanogram amounts of total RNA
Published in American Journal of Physiology: Cell Physiology (01-05-2005)“…Gene expression profiling using microarrays requires microgram amounts of RNA, which limits its direct application for the study of nanogram RNA samples…”
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14
Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism
Published in Tobacco control (01-11-2016)“…BackgroundNicotine is a major oral irritant in smokeless tobacco products and has an aversive taste. Mentholated smokeless tobacco products are highly popular,…”
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Marketing of nicotinamide as nicotine replacement in electronic cigarettes and smokeless tobacco
Published in Tobacco prevention & cessation (2024)“…In the United States, the Food and Drug Administration (FDA) requires tobacco product manufacturers to submit Premarket Tobacco Product Applications (PMTA) for…”
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Sodium Channel Activation Augments NMDA Receptor Function and Promotes Neurite Outgrowth in Immature Cerebrocortical Neurons
Published in The Journal of neuroscience (11-03-2009)“…A range of extrinsic signals, including afferent activity, affect neuronal growth and plasticity. Neuronal activity regulates intracellular Ca(2+), and…”
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Asteropsin A: An unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx
Published in Biochimica et biophysica acta (01-03-2013)“…Herein we report the discovery of a cystine-crosslinked peptide from Porifera along with high-quality spatial details accompanied by the description of its…”
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Chemical Adducts of Reactive Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells
Published in Nicotine & tobacco research (15-12-2020)“…Flavor aldehydes in e-cigarettes, including vanillin, ethyl vanillin (vanilla), and benzaldehyde (berry/fruit), rapidly undergo chemical reactions with the…”
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The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
Published in British journal of pharmacology (01-10-2023)“…The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular…”
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Prioritizing Common Terminology and Measures to Advance Research on Oral Nicotine Product Use
Published in Nicotine & tobacco research (22-04-2024)“…This commentary calls for consistent measurement of oral nicotine product use by the scientific community, recommends specific measures where possible, and…”
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