Search Results - "Jaakkola, Olli"

Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells by Solakivi, Tiina, Kunnas, Tarja, Kärkkäinen, Satu, Jaakkola, Olli, Nikkari, Seppo T

“…Dietary fatty acids may modulate inflammation in macrophages of the atherosclerotic plaque, affecting its stability. The n-6 polyunsaturated fatty acid (PUFA)…”
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Paraoxonase gene polymorphisms and coronary reactivity in young healthy men by MALIN, Riikka, KNUUTI, Juhani, LEHTIMÄKI, Terho, JANATUINEN, Tuula, LAAKSONEN, Reijo, VESALAINEN, Risto, NUUTILA, Pirjo, JOKELA, Hannu, LAAKSO, Juha, JAAKKOLA, Olli, SOLAKIVI, Tiina

“…This study examined the relationships between paraoxonase genotypes, coronary artery reactivity, and indices of low-density lipoprotein oxidation in healthy…”
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Lipoprotein docosapentaenoic acid is associated with serum matrix metalloproteinase-9 concentration by Solakivi, Tiina, Jaakkola, Olli, Kalela, Anne, Pispa, Mari, Salomäki, Anne, Lehtimäki, Terho, Höyhtyä, Matti, Jokela, Hannu, Nikkari, Seppo T

“…Polyunsaturated fatty acids (PUFA) are thought to play important roles in inflammation. The n-3 series is considered as anti-inflammatory, and some studies…”
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Nitric oxide donor GEA 3162 inhibits endothelial cell-mediated oxidation of low density lipoprotein by Malo-Ranta, Ulla, Ylä-Herttuala, Seppo, Metsä-Ketelä, Timo, Jaakkola, Olli, Moilanen, Eeva, Vuorinen, Pauli, Nikkari, Tapio

“…The effect of a nitric oxide (NO) donor GEA 3162 on the endothelial cell (EC)-mediated oxidation of low density lipoprotein (LDL) was studied. In comparison to…”
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Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro by Solakivi, Tiina, Kunnas, Tarja, Jaakkola, Olli, Renko, Jaana, Lehtimäki, Terho, Nikkari, Seppo T

“…Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not…”
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The effect of proteoglycans, collagen and lysyl oxidase on the metabolism of low density lipoprotein by macrophages by Ylä-Herttuala, S, Jaakkola, O, Solakivi, T, Kuivaniemi, H, Nikkari, T

“…To study the interactions of lipoproteins, connective tissue components and cells, mouse peritoneal macrophages were incubated in the presence of human low…”
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Autoantibodies Against Oxidized Low Density Lipoprotein in Patients With Angiographically Verified Coronary Artery Disease by Lehtimaki, Terho, Lehtinen, Saara, Solakivi, Tiina, Nikkila, Matti, Jaakkola, Olli, Jokela, Hannu, Yla-Herttuala, NA, Luoma, Jukka S, Koivula, Timo, Nikkari, Tapio

“…Oxidation of low density lipoproteins (LDL) obviously plays an important role in the pathogenesis of atherosclerosis. The purpose of the study was to determine…”
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ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study by Levula, Mari, Airla, Nina, Oksala, Niku, Hernesniemi, Jussi A, Pelto-Huikko, Markku, Salenius, Juha-Pekka, Zeitlin, Rainer, Järvinen, Otso, Huovila, Ari-Pekka J, Nikkari, Seppo T, Jaakkola, Olli, Ilveskoski, Erkki, Mikkelsson, Jussi, Perola, Markus, Laaksonen, Reijo, Kytömäki, Leena, Soini, Juhani T, Kähönen, Mika, Parkkinen, Jyrki, Karhunen, Pekka J, Lehtimäki, Terho

“…Previously, we scanned all 23,000 human genes for differential expression between normal and atherosclerotic tissues and found the involvement of ADAM8. We…”
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Receptor-mediated binding and degradation of subfractions of human plasma low-density lipoprotein by cultured fibroblasts by Jaakkola, O, Solakivi, T, Ylä-Herttuala, S, Nikkari, T

“…The receptor-mediated metabolism of human plasma low-density lipoprotein (LDL) subfractions was studied. LDL was isolated from healthy donors and further…”
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ALCOHOL MISUSE INCREASES SERUM ANTIBODIES TO OXIDIZED LDL AND C-REACTIVE PROTEIN by ALHO, HANNU, SILLANAUKEE, PEKKA, KALELA, ANNE, JAAKKOLA, OLLI, LAINE, SEPPO, NIKKARI, SEPPO T.

“…Aims: To clarify the relationship of alcohol consumption with serum antibodies to oxidized low-density lipoprotein (oxLDL) and the inflammation marker…”
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Antibodies against copper‐oxidised and malondialdehyde‐modified low density lipoproteins in pre‐eclamptic pregnancies by Uotila, Jukka, Solakivi, Tiina, Jaakkola, Olli, Tuimala, Risto, Lehtimaki, Terho

“…Objective To measure auto‐antibodies against oxidatively modified low density lipoprotein (LDL) in pre‐eclamptic pregnancies using two different techniques…”
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Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis by Rontu, Riikka, Metso, Saara, Jaakkola, Olli, Nikkilä, Matti, Jokela, Hannu, Lehtimäki, Terho

“…Antibody titer against malondialdehyde (MDA)-modified low-density lipoprotein (LDL) has been found to be associated with atherosclerosis, but it has not been…”
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Myeloperoxidase gene variation and coronary flow reserve in young healthy men by Mäkelä, Riikka, Laaksonen, Reijo, Janatuinen, Tuula, Vesalainen, Risto, Nuutila, Pirjo, Jaakkola, Olli, Knuuti, Juhani, Lehtimäki, Terho

“…Chronic inflammation may lead to endothelial dysfunction, which manifests as an impaired coronary reactivity. Impairment in coronary flow reserve (CFR),…”
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Oxidized LDL autoantibodies are related to apolipoprotein E phenotype, independently of postprandial change in plasma triglycerides and LDL size, among patients with angiographically verified coronary artery disease and healthy controls by Metso, Saara, Nikkilä, Matti, Laippala, Pekka, Jaakkola, Olli, Solakivi, Tiina, Lehtimäki, Terho

“…Oxidized low-density lipoprotein (LDL) autoantibodies (oxLDLab), apolipoprotein E (apoE) phenotype, postprandial triglyceride changes and LDL size are…”
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Oxidized low-density lipoprotein is chemotactic for arterial smooth muscle cells in culture by Autio, Ismo, Jaakkola, Olli, Solakivi, Tiina, Nikkari, Tapio

“…The effects of human native and Cu 2+-oxidized low-density lipoprotein (LDL) were tested on the migration of cultured bovine aortic smooth muscle cells (SMCs)…”
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Large-displacement modelling and simulation of micromechanical electrostatically driven resonators using the harmonic balance method by Veijola, T., Mattila, T., Jaakkola, O., Kiihamaki, J., Lamminmaki, T., Oja, A., Ruokonen, K., Seppa, H., Seppala, P., Tittonen, I.

“…Nonlinearities in electrostatically driven micromechanical resonators are studied with circuit simulations. Models for the resonators are built of elementary…”
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The relation of oxidized LDL autoantibodies and long-term hormone replacement therapy to ultrasonographically assessed atherosclerotic plaque quantity and severity in postmenopausal women by Koivu, Tommi A., Dastidar, Prasun, Jokela, Hannu, Nikkari, Seppo T., Jaakkola, Olli, Koivula, Timo, Punnonen, Reijo, Lehtimäki, Terho

“…Background: In epidemiologic studies, the incidence of atherosclerosis rises soon after menopause in women, and hormone replacement therapy (HRT) has proved to…”
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Metabolism of modified LDL and foam cell formation in murine macrophage-like raw 264 cells by Ylitalo, Ritva, Jaakkola, Olli, Lehtolainen, Pauliina, Ylä-Herttuala, Seppo

“…The uptake of modified low density lipoprotein (LDL) by arterial macrophages is a key event in the atherogenesis. We studied 1) the uptake and degradation of…”
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Autoimmune Responses Against Oxidant Stress and Acetaldehyde-Derived Epitopes in Human Alcohol Consumers by Viitala, Katja, Makkonen, Kati, Israel, Yedy, Lehtimäki, Terho, Jaakkola, Olli, Koivula, Timo, Blake, Joan E., Niemelä, Onni

“…Background: Studies in experimental animals have indicated that chronic ethanol ingestion triggers the formation of antibodies directed against proteins…”
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Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers by VIITALA, K, MAKKONEN, K, ISRAEL, Y, LEHTIMÄKI, T, JAAKKOLA, O, KOIVULA, T, BLAKE, J. E, NIEMELÄ, O

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