Search Results - "Jäger, Marcus"

Cotranslational protein folding on the ribosome monitored in real time by Holtkamp, Wolf, Kokic, Goran, Jäger, Marcus, Mittelstaet, Joerg, Komar, Anton A, Rodnina, Marina V

“…Protein domains can fold into stable tertiary structures while they are synthesized on the ribosome. We used a high-performance, reconstituted in vitro…”
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The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines by Landgraeber, Stefan, Jäger, Marcus, Jacobs, Joshua J., Hallab, Nadim James

“…All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow…”
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Functionalization of Synthetic Bone Substitutes by Busch, André, Jäger, Marcus, Mayer, Constantin, Sowislok, Andrea

“…Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized…”
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Slow Unfolded-State Structuring in Acyl-CoA Binding Protein Folding Revealed by Simulation and Experiment by Voelz, Vincent A, Jäger, Marcus, Yao, Shuhuai, Chen, Yujie, Zhu, Li, Waldauer, Steven A, Bowman, Gregory R, Friedrichs, Mark, Bakajin, Olgica, Lapidus, Lisa J, Weiss, Shimon, Pande, Vijay S

“…Protein folding is a fundamental process in biology, key to understanding many human diseases. Experimentally, proteins often appear to fold via simple two- or…”
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Modifications to advanced Core decompression for treatment of Avascular necrosis of the femoral head by Landgraeber, Stefan, Warwas, Sebastian, Claßen, Tim, Jäger, Marcus

“…"Advanced Core Decompression" (ACD) is a new technique for treatment of osteonecrosis of the femoral head (ONFH) that includes removal of the necrotic tissue…”
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Antimicrobial and Osseointegration Properties of Nanostructured Titanium Orthopaedic Implants by Jäger, Marcus, Jennissen, Herbert P, Dittrich, Florian, Fischer, Alfons, Köhling, Hedda Luise

“…The surface design of titanium implants influences not only the local biological reactions but also affects at least the clinical result in orthopaedic…”
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Single-Molecule Fluorescence Studies of Protein Folding and Conformational Dynamics by Michalet, Xavier, Weiss, Shimon, Jäger, Marcus

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A network of trans-cortical capillaries as mainstay for blood circulation in long bones by Grüneboom, Anika, Hawwari, Ibrahim, Weidner, Daniela, Culemann, Stephan, Müller, Sylvia, Henneberg, Sophie, Brenzel, Alexandra, Merz, Simon, Bornemann, Lea, Zec, Kristina, Wuelling, Manuela, Kling, Lasse, Hasenberg, Mike, Voortmann, Sylvia, Lang, Stefanie, Baum, Wolfgang, Ohs, Alexandra, Kraff, Oliver, Quick, Harald H., Jäger, Marcus, Landgraeber, Stefan, Dudda, Marcel, Danuser, Renzo, Stein, Jens V., Rohde, Manfred, Gelse, Kolja, Garbe, Annette I., Adamczyk, Alexandra, Westendorf, Astrid M., Hoffmann, Daniel, Christiansen, Silke, Engel, Daniel Robert, Vortkamp, Andrea, Krönke, Gerhard, Herrmann, Martin, Kamradt, Thomas, Schett, Georg, Hasenberg, Anja, Gunzer, Matthias

“…Closed circulatory systems underlie the function of vertebrate organs, but in long bones their structure is unclear although they constitute the exit route for…”
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Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro by Rehage, Emely, Sowislok, Andrea, Busch, André, Papaeleftheriou, Eleftherios, Jansen, Melissa, Jäger, Marcus

“…There is evidence that surgical site tissue (SSRT) released during orthopedic surgery has a strong mesenchymal regenerative potential. Some data also suggest…”
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Mesenchymal stem cells augment the anti-bacterial activity of neutrophil granulocytes by Brandau, Sven, Jakob, Mark, Bruderek, Kirsten, Bootz, Friedrich, Giebel, Bernd, Radtke, Stefan, Mauel, Katharina, Jäger, Marcus, Flohé, Stefanie B, Lang, Stephan

“…Mesenchymal stem cells (MSCs) participate in the regulation of inflammation and innate immunity, for example by responding to pathogen-derived signals and by…”
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Identification of hospitalized elderly patients at risk for adverse in-hospital outcomes in a university orthopedics and trauma surgery environment by Gronewold, Janine, Dahlmann, Christian, Jäger, Marcus, Hermann, Dirk M

“…As a consequence of demographic changes, hospitals are confronted with increasing numbers of elderly patients, who are at high risk of adverse events during…”
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Ceramic Scaffolds in a Vacuum Suction Handle for Intraoperative Stromal Cell Enrichment by Busch, André, Herten, Monika, Haversath, Marcel, Kaiser, Christel, Brandau, Sven, Jäger, Marcus

“…During total joint replacement, high concentrations of mesenchymal stromal cells (MSCs) are released at the implantation site. They can be found in cell-tissue…”
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Arthroscopic three-dimensional autologous chondrocyte transplantation using spheroids for the treatment of full-thickness cartilage defects of the hip joint by Körsmeier, Konrad, Claßen, Tim, Kamminga, Michael, Rekowski, Jan, Jäger, Marcus, Landgraeber, Stefan

“…Purpose Treatment of full-thickness cartilage defects in the hip is a major issue for orthopaedic surgeons. Autologous matrix-induced three-dimensional…”
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Is Procalcitonin (PCT) a reliable biomarker for preoperative diagnosing of low grade periprosthetic joint infection? A prospective study by Busch, André, Jäger, Marcus, Engler, Harald, Haversath, Marcel, Bielefeld, Charlotte, Landgraeber, Stefan, Wegner, Alexander

“…Since a "gold-standard" is missing, diagnosing periprosthetic joint infection (PJI) remains a challenge in orthopedic surgery. The purpose of this study was to…”
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Transforaminal lumbar interbody fusion with expandable cages: Radiological and clinical results of banana-shaped and straight implants by Tassemeier, Tjark, Haversath, Marcel, Jäger, Marcus

“…Purpose: Expandable titanium transforaminal lumbar interbody fusion (TLIF) devices are a relatively new group of implants allowing restoration of lumbar…”
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Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant Failure by Sowislok, Andrea, Busch, André, Kaschani, Farnusch, Kaiser, Markus, Jäger, Marcus

“…Implant loosening is a severe complication after total joint replacement. Here, differential diagnosis between septic and aseptic cases is crucial for further…”
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Acute traumatic patellar tendon rupture and simultaneous fracture of the tibial tubercle avulsion in a premature soccer player by Mayer, Constantin, Nolte-Boenigk, Louisa, Stanjek, Matthias, Klingler, Anika, Jäger, Marcus

“…Bone-tendon junctions are prone for acute trauma due to its structural weakness, especially in premature males. For the lower limb, the most eminent area is…”
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Evaluation of intra- and interobserver reliability in the assessment of the 'critical trochanter angle' by Serong, Sebastian, Schutzbach, Moritz, Zovko, Ivica, Jäger, Marcus, Landgraeber, Stefan, Haversath, Marcel

“…The recently described 'critical trochanter angle' (CTA) is a novel parameter in the preoperative risk assessment of stem malalignment in total hip…”
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The 'critical trochanter angle': a predictor for stem alignment in total hip arthroplasty by Haversath, Marcel, Busch, André, Jäger, Marcus, Tassemeier, Tjark, Brandenburger, Daniel, Serong, Sebastian

“…Stem malalignment can affect offset reconstruction and may result in gluteal muscle insufficiency. In this retrospective study, a novel geometric angle named…”
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Structure-Function-Folding Relationship in a WW Domain by Jäger, Marcus, Zhang, Yan, Bieschke, Jan, Nguyen, Houbi, Dendle, Maria, Bowman, Marianne E., Noel, Joseph P., Gruebele, Martin, Kelly, Jeffery W.

“…Protein folding barriers result from a combination of factors including unavoidable energetic frustration from nonnative interactions, natural variation and…”
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