Search Results - "Jażdżewski, Krystian"

The rs2910164 Genetic Variant of miR-146a-3p Is Associated with Increased Overall Mortality in Patients with Follicular Variant Papillary Thyroid Carcinoma by Kotlarek, Marta, Kubiak, Anna, Czetwertyńska, Małgorzata, Świerniak, Michał, Gierlikowski, Wojciech, Kolanowska, Monika, Bakuła-Zalewska, Elwira, Jhiang, Sissy M, Jażdżewski, Krystian, Wójcicka, Anna

“…Aberrant expression of the sodium-iodide symporter (NIS) and the resistance to post-operative radioactive iodide treatment is a crucial cause of higher…”
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Circular RNAs Could Encode Unique Proteins and Affect Cancer Pathways by Crudele, Francesca, Bianchi, Nicoletta, Terrazzan, Anna, Ancona, Pietro, Frassoldati, Antonio, Gasparini, Paolo, D'Adamo, Adamo P, Papaioannou, Dimitrios, Garzon, Ramiro, Wójcicka, Anna, Gaj, Paweł, Jażdżewski, Krystian, Palatini, Jeffrey, Volinia, Stefano

“…circRNAs constitute a novel class of RNA, generally considered as non-coding RNAs; nonetheless, their coding potential has been under scrutiny. In this work,…”
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Variants in the ATM-CHEK2-BRCA1 axis determine genetic predisposition and clinical presentation of papillary thyroid carcinoma by Wójcicka, Anna, Czetwertyńska, Małgorzata, Świerniak, Michał, Długosińska, Joanna, Maciąg, Monika, Czajka, Agnieszka, Dymecka, Kinga, Kubiak, Anna, Kot, Adam, Płoski, Rafał, de la Chapelle, Albert, Jażdżewski, Krystian

“…The risk of developing papillary thyroid carcinoma (PTC), the most frequent form of thyroid malignancy, is elevated up to 8.6‐fold in first‐degree relatives of…”
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BMPR1B gene in brachydactyly type 2–A family with de novo R486W mutation and a disease phenotype by Bednarek, Marcin, Trybus, Marek, Kolanowska, Monika, Koziej, Mateusz, Kiec‐Wilk, Beata, Dobosz, Artur, Kotlarek‐Łysakowska, Marta, Kubiak‐Dydo, Anna, Użarowska‐Gąska, Ewelina, Staręga‐Rosłan, Julia, Gaj, Paweł, Górzyńska, Izabela, Serwan, Katarzyna, Świerniak, Michał, Kot, Adam, Jażdżewski, Krystian, Wójcicka, Anna

“…Background Brachydactylies are a group of inherited conditions, characterized mainly by the presence of shortened fingers and toes. Based on the patients’…”
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Family of microRNA-146 Regulates RARβ in Papillary Thyroid Carcinoma by Czajka, Agnieszka Anna, Wójcicka, Anna, Kubiak, Anna, Kotlarek, Marta, Bakuła-Zalewska, Elwira, Koperski, Łukasz, Wiechno, Wiesław, Jażdżewski, Krystian

“…Retinoic acid is a promising tool in adjuvant cancer therapies, including refractory thyroid cancer, and its biological role is mediated by the retinoic acid…”
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Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma by Jazdzewski, Krystian, Murray, Elizabeth L, Franssila, Kaarle, Jarzab, Barbara, Schoenberg, Daniel R, de la Chapelle, Albert

“…Although papillary thyroid carcinoma (PTC) displays strong heritability, no predisposing germ-line mutations have been found. We show that a common G/C…”
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Polymorphic Mature MicroRNAs from Passenger Strand of Pre-MiR-146a Contribute to Thyroid Cancer by Jazdzewski, Krystian, Liyanarachchi, Sandya, Swierniak, Michal, Pachucki, Janusz, Ringel, Matthew D., Jarzab, Barbara, de la Chapelle, Albert

“…Prior work has shown that heterozygosity G/C of single nucleotide polymorphism (SNP rs2910164) within the precursor of microRNA-146a predisposes to PTC (odds…”
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In-Depth Characterization of the MicroRNA Transcriptome in Normal Thyroid and Papillary Thyroid Carcinoma by Swierniak, Michal, Wojcicka, Anna, Czetwertynska, Malgorzata, Stachlewska, Elzbieta, Maciag, Monika, Wiechno, Wieslaw, Gornicka, Barbara, Bogdanska, Magdalena, Koperski, Lukasz, de la Chapelle, Albert, Jazdzewski, Krystian

“…Context: A single microRNA gene may give rise to several mature products that differ in length, called isomiRs. IsomiRs are known to be tissue specific and…”
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MicroRNA Analysis Using Next-Generation Sequencing by Kolanowska, Monika, Kubiak, Anna, Jażdżewski, Krystian, Wójcicka, Anna

“…Next-generation sequencing (NGS) enables the analysis of both microRNA expression and sequence, allowing for elucidation of a comprehensive landscape of miRNAs…”
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MicroRNA Analysis Using the Quantitative Real-Time PCR Reaction by Kotlarek, Marta, Kubiak, Anna, Jażdżewski, Krystian, Wójcicka, Anna

“…The analysis of microRNA expression patterns provides new insights into numerous cellular processes and their aberrances in diseases. Despite its potential…”
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Next-generation sequencing reveals microRNA markers of adrenocortical tumors malignancy by Koperski, Łukasz, Kotlarek, Marta, Świerniak, Michał, Kolanowska, Monika, Kubiak, Anna, Górnicka, Barbara, Jażdżewski, Krystian, Wójcicka, Anna

“…Adrenocortical carcinoma is a rare finding among common adrenocortical tumors, but it is highly aggressive and requires early detection and treatment. Still,…”
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Next generation sequencing reveals microRNA isoforms in liver cirrhosis and hepatocellular carcinoma by Wojcicka, Anna, Swierniak, Michal, Kornasiewicz, Oskar, Gierlikowski, Wojciech, Maciag, Monika, Kolanowska, Monika, Kotlarek, Marta, Gornicka, Barbara, Koperski, Lukasz, Niewinski, Grzegorz, Krawczyk, Marek, Jazdzewski, Krystian

“…Hepatocellular carcinoma (HCC) represents the major histological subtype of liver cancer. Tumorigenic changes in hepatic cells potentially result from aberrant…”
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The Role of MicroRNA Genes in Papillary Thyroid Carcinoma by He, Huiling, Krystian Jazdzewski, Li, Wei, Liyanarachchi, Sandya, Rebecca Nagy, Volinia, Stefano, Calin, George A., Liu, Chang-gong, Kaarle Franssila, Suster, Saul, Kloos, Richard T., Croce, Carlo M., de la Chapelle, Albert

“…Apart from alterations in the RET/PTC-RAS-BRAF pathway, comparatively little is known about the genetics of papillary thyroid carcinoma (PTC). We show that…”
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Regulatory mechanisms in arterial hypertension: role of microRNA in pathophysiology and therapy by Klimczak, Dominika, Jazdzewski, Krystian, Kuch, Marek

“…Multiple factors underlie the pathophysiology of hypertension, involving endothelial dysregulation, vascular smooth muscle dysfunction, increased oxidative…”
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A Risk of Gonadoblastoma in Familial Swyer Syndrome-A Case Report and Literature Review by Rudnicka, Ewa, Jaroń, Aleksandra, Kruszewska, Jagoda, Smolarczyk, Roman, Jażdżewski, Krystian, Derlatka, Paweł, Kucharska, Anna Małgorzata

“…A complete gonadal dysgenesis (CGD) with 46,XY karyotype is known as the Swyer syndrome and belongs to the group of 46,XY differences of sex development (DSD)…”
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Association between GWAS-Derived rs966423 Genetic Variant and Overall Mortality in Patients with Differentiated Thyroid Cancer by Świerniak, Michał, Wójcicka, Anna, Czetwertyńska, Małgorzata, Długosińska, Joanna, Stachlewska, Elżbieta, Gierlikowski, Wojciech, Kot, Adam, Górnicka, Barbara, Koperski, Łukasz, Bogdańska, Magdalena, Wiechno, Wiesław, Jażdżewski, Krystian

“…Five germline genetic variants (rs116909374, rs965513, rs944289, rs966423, and rs2439302) have been associated in genome-wide association studies (GWAS) with…”
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Functional analysis of a novel, thyroglobulin-embedded microRNA gene deregulated in papillary thyroid carcinoma by Kolanowska, Monika, Wójcicka, Anna, Kubiak, Anna, Świerniak, Michał, Kotlarek, Marta, Maciąg, Monika, Gaj, Paweł, Koperski, Łukasz, Górnicka, Barbara, Jażdżewski, Krystian

“…MicroRNAs, non-coding regulators of gene expression, are known culprits of thyroid cancer. Using next-generation sequencing, we identified a novel microRNA…”
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MicroRNAs: powerful regulators and potential diagnostic tools in cardiovascular disease by Klimczak, Dominika, Pączek, Leszek, Jażdżewski, Krystian, Kuch, Marek

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Association Between Parafibromin Expression and Presence of Brown Tumors and Jaw Tumors in Patients with Primary Hyperparathyroidism: Series of Cases with Review of the Literature by Popow, Michał, Kaszczewska, Monika, Góralska, Magdalena, Kaszczewski, Piotr, Skwarek-Szewczyk, Agata, Chudziński, Witold, Jażdżewski, Krystian, Kolanowska, Monika, Bogdańska, Magdalena, Starzyńska-Kubicka, Aleksandra, Gałązka, Zbigniew

“…Case series Patients: Male, 57-year-old • Male, 42-year-old • Female, 45-year-old • Male, 42-year-old Final Diagnosis: Brown tumor • hyperparathyroidism…”
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MECHANISMS IN ENDOCRINOLOGY: MicroRNA in diagnostics and therapy of thyroid cancer by Wójcicka, Anna, Kolanowska, Monika, Jażdżewski, Krystian

“…MicroRNAs, short non-coding regulators of the gene expression, are subjects of numerous investigations assessing their potential use in the diagnostics and…”
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