Search Results - "Jaźwiec, Radosław"

A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori by Wojtyś, Marta Ilona, Jaźwiec, Radosław, Kazazić, Saša, Leščić Ašler, Ivana, Knežević, Petar, Aleksić Sabo, Verica, Luić, Marija, Jagusztyn-Krynicka, Elżbieta Katarzyna, Bzowska, Agnieszka

“…Due to the growing number of Helicobacter pylori strains resistant to currently available antibiotics, there is an urgent need to design new drugs utilizing…”
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Serum indoxyl sulphate and its relation to albumin and α1-acid  glycoprotein as a potential biomarkers of maternal intestinal metabolism  during pregnancy and postpartum by Lisowska-Myjak, Barbara, Zborowska, Hanna, Jaźwiec, Radosław, Karlińska, Maria, Skarżyńska, Ewa

“…Serum indoxyl sulfate (IS) levels depend on the production of indole in the gut. The biological effects of IS in the vascular bed could be confirmed by changes…”
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Cerebrovascular reactivity and cerebral perfusion of rats with acute liver failure: role of L‐glutamine and asymmetric dimethylarginine in L‐arginine‐induced response by Czarnecka, Anna, Aleksandrowicz, Marta, Jasiński, Krzysztof, Jaźwiec, Radosław, Kalita, Katarzyna, Hilgier, Wojciech, Zielińska, Magdalena

“…Cerebral blood flow (CBF) is impaired in acute liver failure (ALF), however, the complexity of the underlying mechanisms has often led to inconclusive…”
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In vivo assessment of potential for UGT-inhibition-based drug-drug interaction between sorafenib and tapentadol by Karbownik, Agnieszka, Miedziaszczyk, Miłosz, Grabowski, Tomasz, Stanisławiak-Rudowicz, Joanna, Jaźwiec, Radosław, Wolc, Anna, Grześkowiak, Edmund, Szałek, Edyta

“…[Display omitted] •If sorafenib and tapentadol are co-administered in combination therapy, it may be necessary to reduce the dose of the drugs, because of…”
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Expression of maize calcium‐dependent protein kinase (ZmCPK11) improves salt tolerance in transgenic Arabidopsis plants by regulating sodium and potassium homeostasis and stabilizing photosystem II by Borkiewicz, Lidia, Polkowska‐Kowalczyk, Lidia, Cieśla, Jarosław, Sowiński, Paweł, Jończyk, Maciej, Rymaszewski, Wojciech, Szymańska, Katarzyna P., Jaźwiec, Radosław, Muszyńska, Grażyna, Szczegielniak, Jadwiga

“…In plants, CALCIUM‐DEPENDENT PROTEIN KINASES (CDPKs/CPKs) are involved in calcium signaling in response to endogenous and environmental stimuli. Here, we…”
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Ammonia Reduces Intracellular Asymmetric Dimethylarginine in Cultured Astrocytes Stimulating Its y⁺LAT2 Carrier-Mediated Loss by Milewski, Krzysztof, Bogacińska-Karaś, Małgorzata, Fręśko, Inez, Hilgier, Wojciech, Jaźwiec, Radosław, Albrecht, Jan, Zielińska, Magdalena

“…Previously we had shown that ammonia stimulates nitric oxide (NO) synthesis in astrocytes by increasing the uptake of the precursor amino acid, arginine via…”
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Pharmacokinetic Drug Interaction Study of Sorafenib and Morphine in Rats by Karbownik, Agnieszka, Szkutnik-Fiedler, Danuta, Grabowski, Tomasz, Wolc, Anna, Stanisławiak-Rudowicz, Joanna, Jaźwiec, Radosław, Grześkowiak, Edmund, Szałek, Edyta

“…A combination of the tyrosine kinase inhibitor-sorafenib-and the opioid analgesic-morphine-can be found in the treatment of cancer patients. Since both are…”
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Intracerebral Administration of S-Adenosylhomocysteine or S-Adenosylmethionine Attenuates the Increases in the Cortical Extracellular Levels of Dimethylarginines Without Affecting cGMP Level in Rats with Acute Liver Failure by Czarnecka, Anna, Milewski, Krzysztof, Jaźwiec, Radosław, Zielińska, Magdalena

“…Alterations in brain nitric oxide (NO)/cGMP synthesis contribute to the pathogenesis of hepatic encephalopathy (HE). An increased asymmetrically dimethylated…”
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Dose-adjusted and dose/kg-adjusted concentrations of mycophenolic acid precursors reflect metabolic ratios of their metabolites in contrast with tacrolimus and cyclosporine by Hryniewiecka, Ewa, Żegarska, Jolanta, Żochowska, Dorota, Samborowska, Emilia, Jaźwiec, Radosław, Kosieradzki, Maciej, Nazarewski, Sławomir, Dadlez, Michał, Pączek, Leszek

“…Therapeutic drug monitoring is a valuable tool supporting immunosuppressive therapy. Significant variation of immunosuppressive drug (ISD) concentrations…”
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Cyclosporine Metabolites’ Metabolic Ratios May Be Markers of Cardiovascular Disease in Kidney Transplant Recipients Treated with Cyclosporine A-Based Immunosuppression Regimens by Hryniewiecka, Ewa, Żegarska, Jolanta, Żochowska, Dorota, Samborowska, Emilia, Jaźwiec, Radosław, Kosieradzki, Maciej, Nazarewski, Sławomir, Dadlez, Michał, Pączek, Leszek

“…Cardiovascular disease (CVD) remains one of the primary causes of death after kidney transplantation (KTX). Cyclosporine (CsA) metabolites may play a role in…”
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Complement components, proteolysis‑related, and cell communication‑related proteins detected in urine proteomics are associated with IgA nephropathy by Mucha, Krzysztof, Bakun, Magdalena, Jaźwiec, Radosław, Dadlez, Michał, Florczak, Michał, Bajor, Małgorzata, Gala, Kamila, Pączek, Leszek

“…IgA nephropathy (IgAN) is the most common primary glomerulonephritis. The first symptoms of IgAN are erytrocyturia or hematuria, proteinuria, and decline in…”
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LC-MS/MS improves screening towards 21-hydroxylase deficiency by Ambroziak, Urszula, K pczy ska-Nyk, Anna, Kury owicz, Alina, Wys ouch- Cieszy ska, Aleksandra, Ma unowicz, Ewa Maria, Bartoszewicz, Zbigniew, Kondracka, Agnieszka, Ja wiec, Rados aw, Paw owska, Emilia, Szcze niak, Magdalena, Dadlez, Micha, Bednarczuk, Tomasz

“…Abstract Basal serum 17OHP measurement remains the first screening step for nonclassic congenital adrenal hyperplasia (NCCAH) and the accuracy of the test is…”
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Mycophenolic Acid Metabolites Acyl-Glucuronide and Glucoside Affect the Occurrence of Infectious Complications and Bone Marrow Dysfunction in Liver Transplant Recipients by Zegarska, Jolanta, Hryniewiecka, Ewa, Żochowska, Dorota, Tszyrsznic, Wlodzimierz, Jaźwiec, Radosław, Borowiec, Agnieszka, Pawłowska, Emilia, Dadlez, Michał, Pączek, Leszek

“…BACKGROUND Mycophenolic acid (MPA) prodrugs are anti-proliferative immunosuppressive agents commonly used after organ transplantation. Although they are…”
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Total testosterone to dihydrotestosterone ratio assessed by LC-MS/MS predicts a worse metabolic profile not only in PCOS patients by Ambroziak, Urszula, Kuryłowicz, Alina, Kępczyńska-Nyk, Anna, Bartoszewicz, Zbigniew, Kondracka, Agnieszka, Jaźwiec, Radosław, Samborowska, Emilia, Dadlez, Michał, Wysłouch-Cieszyńska, Aleksandra, Bednarczuk, Tomasz

“…Total testosterone/dihydrotestosterone ratio (TT/DHT) was found to determine metabolic risk in polycystic ovary syndrome (PCOS). The aim of this study was to…”
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Can we accurately measure the concentration of clinically relevant vitamin D metabolites in the circulation? The problems and their consequences by Bartoszewicz, Zbigniew, Kondracka, Agnieszka, Jaźwiec, Radosław, Popow, Michał, Dadlez, Michał, Bednarczuk, Tomasz

“…Increased interest in vitamin D measurements in clinical studies has contributed to the development in recent years of several new immunochemical assays…”
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Absorption of Polyunsaturated Fatty Acid (PUFA) Is Related to IgG Blood Levels of Neonatal Pigs during the First 48 Hours Postpartum by Shmigel, Halyna, Jazwiec, Radosław, Weström, Björn, Woliński, Jarosław, Pierzynowska, Kateryna, Pierzynowski, Stefan G.

“…The current study is aimed at highlighting the impact of enterally or parenterally applied immunoglobulins (Igs) on polyunsaturated fatty acid (PUFA)…”
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Serum indoxyl sulphate and its relation to albumin and α1-acid  glycoprotein as a potential biomarkers of maternal intestinal metabolism  during pregnancy and postpartum by Barbara Lisowska-Myjak, Hanna Zborowska, Radosław Jaźwiec, Maria Karlińska, Ewa Skarżyńska

“…BackgroundSerum indoxyl sulfate (IS) levels depend on the production of indole in the gut. The biological effects of IS in the vascular bed could be confirmed…”
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Trimethylamine-N-Oxide: A Carnitine-Derived Metabolite That Prolongs the Hypertensive Effect of Angiotensin II in Rats by Ufnal, Marcin, PhD, MD, Jazwiec, Radoslaw, MSc, Dadlez, Michal, PhD, Drapala, Adrian, MD, Sikora, Mariusz, MD, Skrzypecki, Janusz, MD

“…Abstract Background Recent evidence suggests that an elevated plasma trimethylamine N-oxide (TMAO) level is associated with an increased risk of adverse…”
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Serum indoxyl sulphate and its relation to albumin and [alpha].sub.1-acid glycoprotein as a potential biomarkers of maternal intestinal metabolism during pregnancy and postpartum by Lisowska-Myjak, Barbara, Zborowska, Hanna, Jazwiec, Radoslaw, Karlinska, Maria, Skarzynska, Ewa

“…Background Serum indoxyl sulfate (IS) levels depend on the production of indole in the gut. The biological effects of IS in the vascular bed could be confirmed…”
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Two rapid ultra performance liquid chromatography/tandem mass spectrometry (UPLC/MS/MS) methods with common sample pretreatment for therapeutic drug monitoring of immunosuppressants compared to immunoassay by Tszyrsznic, Wlodzimierz, Borowiec, Agnieszka, Pawlowska, Emilia, Jazwiec, Radoslaw, Zochowska, Dorota, Bartlomiejczyk, Irena, Zegarska, Jolanta, Paczek, Leszek, Dadlez, Michal

“…•Application of UPLC/MS/MS in therapeutic drug monitoring of four immunosuppressants in whole blood and one in blood plasma.•Comparison of results obtained…”
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