Search Results - "JURASZ, P."

The potential of enzastaurin to enhance platelet aggregation and growth factor secretion: implications for cancer cell survival by Lesyk, G., Fong, T., Ruvolo, P. P., Jurasz, P.

“…Summary Background Enzastaurin is a protein kinase C (PKC)β inhibitor with antiproliferative and proapoptotic effects that was in clinical development for the…”
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PHARMACOLOGICAL CHARACTERIZATION OF THE FUNCTIONAL ROLE OF CALCIUM-ACTIVATED POTASSIUM CHANNELS IN PLATELETS by Back, V, Plane, F, Jurasz, P

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Generation of platelet angiostatin mediated by urokinase plasminogen activator: effects on angiogenesis by JURASZ, P., SANTOS‐MARTINEZ, M. J., RADOMSKA, A., RADOMSKI, M. W.

“…Background: Angiogenesis, the growth of new capillaries from pre‐existing blood vessels, is regulated by a balance between its promoters and inhibitors…”
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522 Characterization of Platelet Subpopulations Based on the Heterogeneity of NOS Signalling by Radziwon-Balicka, A, El-Sikhry, H, Zielnik, B, Ogg, S, Seubert, J, Jurasz, P

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PB0601 Identification of a Novel Growth Factor-Enriched Platelet Subpopulation: Potential Implications for COVID-19 by Asgari, A., Jurasz, P.

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OC 22.5 Effect of Angiostatin and its Neutralization on Cellular Infection by SARS-CoV and SARS-CoV-2 by Franczak, A., Joyce, M., Saito, M., Tyrrell, L., Jurasz, P.

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SELECTIVE ANGIOSTATIN NEUTRALIZATION PROMOTES ENDOTHELIAL MIGRATION AN EARLY STAGE OF ANGIOGENESIS by Govindasamy, N., Chatterjee, K., Lesyk, G., Kalyaanamoorthy, S., Barakat, K., Jurasz, P.

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Nanoparticle‐induced platelet aggregation and vascular thrombosis by Radomski, Anna, Jurasz, Paul, Alonso‐Escolano, David, Drews, Magdalena, Morandi, Maria, Malinski, Tadeusz, Radomski, Marek W

“…Ever increasing use of engineered carbon nanoparticles in nanopharmacology for selective imaging, sensor or drug delivery systems has increased the potential…”
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Platelet–cancer interactions: mechanisms and pharmacology of tumour cell‐induced platelet aggregation by Jurasz, Paul, Alonso‐Escolano, David, Radomski, Marek W

“…During haematogenous metastasis, cancer cells migrate to the vasculature and interact with platelets resulting in tumour cell‐induced platelet aggregation…”
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Decreased platelet nitric oxide synthase activity and plasma nitric oxide metabolites in major depressive disorder by Chrapko, Wendy E, Jurasz, Paul, Radomski, Marek W, Lara, Nathalie, Archer, Stephen L, Le Mellédo, Jean-Michel

“…Major depression (MD) has been associated with increased cardiovascular mortality in patients with coronary heart disease (CHD) and has been described as an…”
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Platelet aggregation-induced by caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate by Medina, Carlos, Jurasz, Paul, Santos-Martinez, Maria Jose, Jeong, Soon Seog, Mitsky, Timothy, Chen, Ridong, Radomski, Marek W

“…Formation of tumor cell-platelet aggregates facilitates hematogenous metastases. However, molecular mechanisms implicated in tumor cell-induced platelet…”
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Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation : Regulation by nitric oxide by JURASZ, Paul, SAWICKI, Grzegorz, DUSZYK, Marek, SAWICKA, Jolanta, MIRANDA, Carlos, MAYERS, Irvin, RADOMSKI, Marek W

“…A correlation exists between the ability of tumor cells to aggregate platelets and their tendency to metastasize. Tumor cell-induced platelet aggregation…”
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Generation and role of angiostatin in human platelets by Jurasz, Paul, Alonso, David, Castro-Blanco, Susana, Murad, Ferid, Radomski, Marek W.

“…Platelets regulate new blood vessel growth, because they contain a number of angiogenesis promoters and inhibitors. Additionally, platelets contain matrix…”
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Platelet–leukocyte aggregation induced by PAR agonists: regulation by nitric oxide and matrix metalloproteinases by Chung, Ada W Y, Radomski, Anna, Alonso‐Escolano, David, Jurasz, Paul, Stewart, Michael W, Malinski, Tadeusz, Radomski, Marek W

“…Platelet–leukocyte aggregation (PLA) links haemostasis to inflammation. The role of nitric oxide (NO) and matrix metalloproteinases (MMP‐1, ‐2, ‐3, ‐9) in PLA…”
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Mechanisms of action of proteinase‐activated receptor agonists on human platelets by Chung, Ada W Y, Jurasz, Paul, Hollenberg, Morley D, Radomski, Marek W

“…We studied the activation of human platelets by thrombin and proteinase activated receptor (PAR)‐activating peptides (PAR‐APs) [SFLLRNPNDKYEPF‐amide (TRAP),…”
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Identification, regulation and role of tissue inhibitor of metalloproteinases‐4 (TIMP‐4) in human platelets by Radomski, Anna, Jurasz, Paul, Sanders, Esmond J, Overall, Christopher M, Bigg, Heather F, Edwards, Dylan R, Radomski, Marek W

“…Matrix metalloproteinase‐2 (MMP‐2) released during activation of human platelets by aggregating agents and cancer cells is known to stimulate platelet…”
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Nonremodeling Properties of Matrix Metalloproteinases: The Platelet Connection by Jurasz, Paul, Chung, Ada W.Y, Radomski, Anna, Radomski, Marek W

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Pharmacological characteristics of solid‐phase von Willebrand factor in human platelets by Radomski, Anna, Stewart, Michael W, Jurasz, Paul, Radomski, Marek W

“…The pharmacological characteristics of solid‐phase von Willebrand factor (svWF), a novel platelet agonist, were studied. Washed platelet suspensions were…”
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Matrix metalloproteinase-2 contributes to increased platelet reactivity in patients with metastatic prostate cancer: a preliminary study by Jurasz, Paul, North, Scott, Venner, Peter, Radomski, Marek W

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Role of von Willebrand factor in tumour cell‐induced platelet aggregation: differential regulation by NO and prostacyclin by Jurasz, Paul, Stewart, Michael W, Radomski, Anna, Khadour, Fadi, Duszyk, Marek, Radomski, Marek W

“…We have studied the effects of a novel agonist, solid‐phase von Willebrand Factor (sVWF), on tumour cell‐induced platelet aggregation (TCIPA). Washed platelet…”
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