Search Results - "JUNYING ZHENG"

Senescence of endplate osteoclasts induces sensory innervation and spinal pain by Pan, Dayu, Benkato, Kheiria Gamal, Han, Xuequan, Zheng, Jinjian, Kumar, Vijay, Wan, Mei, Zheng, Junying, Cao, Xu

“…Spinal pain affects individuals of all ages and is the most common musculoskeletal problem globally. Its clinical management remains a challenge as the…”
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Unloading‐Induced Skeletal Interoception Alters Hypothalamic Signaling to Promote Bone Loss and Fat Metabolism by Guo, Qiaoyue, Chen, Ningrong, Patel, Kalp, Wan, Mei, Zheng, Junying, Cao, Xu

“…Microgravity is the primary factor that affects human physiology in spaceflight, particularly bone loss and disturbances of the central nervous system…”
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Increased talin–vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections by Liu, Yakun, Xiao, Jie, Zhang, Ben, Shelite, Thomas R., Su, Zhengchen, Chang, Qing, Judy, Barbara, Li, Xiang, Drelich, Aleksandra, Bei, Jiani, Zhou, Yixuan, Zheng, Junying, Jin, Yang, Rossi, Shannan L., Tang, Shao-Jun, Wakamiya, Maki, Saito, Tais, Ksiazek, Thomas, Kaphalia, Bhupendra, Gong, Bin

“…Talin and vinculin, both actin-cytoskeleton-related proteins, have been documented to participate in establishing bacterial infections, respectively, as the…”
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Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses by Zheng, Junying, Wang, Junru, Pouliot, Mylene, Authier, Simon, Zhou, Daohong, Loose, David S, Hauer-Jensen, Martin

“…Although extensive studies have investigated radiation-induced injuries in particular gastrointestinal (GI) segments, a systematic comparison among the…”
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Cell-Type Apoptosis in Lung during SARS-CoV-2 Infection by Liu, Yakun, Garron, Tania M, Chang, Qing, Su, Zhengchen, Zhou, Changcheng, Qiu, Yuan, Gong, Eric C, Zheng, Junying, Yin, Y Whitney, Ksiazek, Thomas, Brasel, Trevor, Jin, Yang, Boor, Paul, Comer, Jason E, Gong, Bin

“…The SARS-CoV-2 pandemic has inspired renewed interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS) following…”
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Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain by Gao, Feng, Hu, Qimiao, Chen, Wenwei, Li, Jilong, Qi, Cheng, Yan, Yiwen, Qian, Cheng, Wan, Mei, Ficke, James, Zheng, Junying, Cao, Xu

“…Bone is a mechanosensitive tissue and undergoes constant remodeling to adapt to the mechanical loading environment. However, it is unclear whether the signals…”
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Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog by Zheng, Junying, Wei, Chih-Chang, Hase, Naoki, Shi, Ke, Killingsworth, Cheryl R, Litovsky, Silvio H, Powell, Pamela C, Kobayashi, Tsunefumi, Ferrario, Carlos M, Rab, Andras, Aban, Inmaculada, Collawn, James F, Dell'Italia, Louis J

“…Cardiac ischemia and reperfusion (I/R) injury occurs because the acute increase in oxidative/inflammatory stress during reperfusion culminates in the death of…”
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Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia by Zheng, Junying, Ru, Wenjuan, Adolacion, Jay R., Spurgat, Michael S., Liu, Xin, Yuan, Subo, Liang, Rommel X., Dong, Jianli, Potter, Andrew S., Potter, S Steven, Chen, Ken, Chen, Rui, Varadarajan, Navin, Tang, Shao-Jun

“…Microglia are ubiquitous central nervous system (CNS)-resident macrophages that maintain homeostasis of neural tissues and protect them from pathogen attacks…”
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Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss by Wei, Chih-Chang, Chen, Yuanwen, Powell, Lindsay C, Zheng, Junying, Shi, Ke, Bradley, Wayne E, Powell, Pamela C, Ahmad, Sarfaraz, Ferrario, Carlos M, Dell'Italia, Louis J

“…The clinical problem of a "pure volume overload" as in isolated mitral or aortic regurgitation currently has no documented medical therapy that attenuates…”
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Development of a prognostic composite cytokine signature based on the correlation with nivolumab clearance: translational PK/PD analysis in patients with renal cell carcinoma by Wang, Rui, Zheng, Junying, Shao, Xiao, Ishii, Yuko, Roy, Amit, Bello, Akintunde, Lee, Richard, Zhang, Joshua, Wind-Rotolo, Megan, Feng, Yan

“…BackgroundAlthough several therapeutic options for patients with renal cell carcinoma (RCC) have been approved over recent years, including immune checkpoint…”
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Microarray Identifies Extensive Downregulation of Noncollagen Extracellular Matrix and Profibrotic Growth Factor Genes in Chronic Isolated Mitral Regurgitation in the Dog by JUNYING ZHENG, YUANWEN CHEN, HUSAIN, Ahsan, DELL'ITALIA, Louis J, PAT, Betty, DELL'ITALIA, Louis A, TILLSON, Michael, DILLON, A. Ray, POWELL, Pamela C, KE SHI, SHAH, Neil, DENNEY, Thomas

“…The volume overload of isolated mitral regurgitation (MR) in the dog results in left ventricular (LV) dilatation and interstitial collagen loss. To better…”
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Roles of Sensory Nerves in the Regulation of Radiation-Induced Structural and Functional Changes in the Heart by Sridharan, Vijayalakshmi, PhD, Tripathi, Preeti, MS, Sharma, Sunil, PhD, Moros, Eduardo G., PhD, Zheng, Junying, PhD, Hauer-Jensen, Martin, MD, PhD, Boerma, Marjan, PhD

“…Purpose Radiation-induced heart disease (RIHD) is a chronic severe side effect of radiation therapy of intrathoracic and chest wall tumors. The heart contains…”
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Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestine by Zheng, Junying, Garg, Sarita, Wang, Junru, Loose, David S, Hauer-Jensen, Martin

“…The intestinal mucosa is the compartment that sustains the most severe injury in response to radiation and is therefore of primary interest. The use of whole…”
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Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload by Ulasova, Elena, Gladden, James D, Chen, Yuanwen, Zheng, Junying, Pat, Betty, Bradley, Wayne, Powell, Pamela, Zmijewski, Jaroslaw W, Zelickson, Blake R, Ballinger, Scott W, Darley-Usmar, Victor, Dell'Italia, Louis J

“…Abstract Volume overload (VO) caused by aortocaval fistula (ACF) is associated with oxidative/inflammatory stress. The resulting inflammation, matrix…”
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Chymase Inhibition Prevents Fibronectin and Myofibrillar Loss and Improves Cardiomyocyte Function and LV Torsion Angle in Dogs With Isolated Mitral Regurgitation by PAT, Betty, YUANWEN CHEN, DESAI, Ravi, WEI, Chih-Chang, HASE, Naoki, KOBAYASHI, Tsunefumi, SABRI, Abdelkarim, GRANZIER, Henk, DENNEY, Thomas, TILLSON, Michael, RAY DILLON, A, HUSAIN, Ahsan, KILLINGSWORTH, Cheryl, DELL'ITALIA, Louis J, GLADDEN, James D, KE SHI, JUNYING ZHENG, POWELL, Pamela C, WALCOTT, Greg, AHMED, Mustafa I, GUPTA, Himanshu

“…The left ventricular (LV) dilatation of isolated mitral regurgitation (MR) is associated with an increase in chymase and a decrease in interstitial collagen…”
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Polymeric Structure and Host Toll-like Receptor 4 Dictate Immunogenicity of NY-ESO-1 Antigen in Vivo by Liu, Yanan, Tian, Xiaoli, Leitner, Wolfgang W., Aldridge, Michael E., Zheng, Junying, Yu, Zhiya, Restifo, Nicholas P., Weiss, Richard, Scheiblhofer, Sandra, Xie, Chong, Sun, Ren, Cheng, Genhong, Zeng, Gang

“…In search of intrinsic factors that contribute to the distinctively strong immunogenicity of a non-mutated cancer/testis antigen, we found that NY-ESO-1 forms…”
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Molecular cloning of a putative crustacean hyperglycemic hormone (CHH) isoform from extra-eyestalk tissue of the blue crab ( Callinectes sapidus ), and determination of temporal and spatial patterns of CHH gene expression by Zheng, Junying, Chen, Hsiang-Yin, Choi, Cheol Young, Roer, Robert D, Watson, R. Douglas

“…Abstract Crustacean hyperglycemic hormone (CHH) is a polypeptide neurohormone involved in regulation of multiple physiological processes. We report here the…”
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Total synthesis of (−)-salicylihalamide A and related congeners by Smith, Amos B, Zheng, Junying

“…A concise, highly efficient total synthesis of (−)-salicylihalamide A ( 1 ), a novel marine sponge metabolite, has been achieved. Key features of the synthetic…”
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Molecular cloning of a cDNA encoding a crustacean hyperglycemic hormone from eyestalk ganglia of the blue crab, Callinectes sapidus by Choi, Cheol Young, Zheng, Junying, Watson, R. Douglas

“…Crustacean hyperglycemic hormone (CHH), a polypeptide with multiple physiological effects, was first identified in the X-organ/sinus gland neurosecretory…”
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Studies of a receptor guanylyl cyclase cloned from Y-organs of the blue crab ( Callinectes sapidus ), and its possible functional link to ecdysteroidogenesis by Zheng, Junying, Nakatsuji, Teruaki, Roer, Robert D, Watson, R. Douglas

“…Abstract Crustacean Y-organs synthesize ecdysteroid molting hormones. Synthesis of ecdysteroids by Y-organs is negatively regulated by a polypeptide…”
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