Search Results - "JUNSHU YANG"

Application of Mycobacterium smegmatis as a surrogate to evaluate drug leads against Mycobacterium tuberculosis by Lelovic, Nada, Mitachi, Katsuhiko, Yang, Junshu, Lemieux, Maddie R., Ji, Yinduo, Kurosu, Michio

“…Discovery of new anti-tuberculosis (TB) drugs is a time-consuming process due to the slow-growing nature of Mycobacterium tuberculosis (Mtb). A requirement of…”
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The Staphylococcus aureus AirSR Two-Component System Mediates Reactive Oxygen Species Resistance via Transcriptional Regulation of Staphyloxanthin Production by Hall, Jeffrey W, Yang, Junshu, Guo, Haiyong, Ji, Yinduo

“…Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden…”
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Antibacterial Activity of Pharmaceutical-Grade Rose Bengal: An Application of a Synthetic Dye in Antibacterial Therapies by Kurosu, Michio, Mitachi, Katsuhiko, Yang, Junshu, Pershing, Edward V, Horowitz, Bruce D, Wachter, Eric A, Lacey, 3rd, John W, Ji, Yinduo, Rodrigues, Dominic J

“…Rose bengal has been used in the diagnosis of ophthalmic disorders and liver function, and has been studied for the treatment of solid tumor cancers. To date,…”
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Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages by Qiu, Xiaoxue, Guo, Hong, Yang, Junshu, Ji, Yinduo, Wu, Chia-Shan, Chen, Xiaoli

“…Macrophage polarization is tightly associated with its metabolic reprograming and immune dysfunction. However, the intracellular molecules/pathways that…”
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Broad-Spectrum Antibacterial Activity of Antioxidant Octyl Gallate and Its Impact on Gut Microbiome by Yang, Junshu, Gould, Trevor J, Jeon, Byeonghwa, Ji, Yinduo

“…In this study, we investigated the antibacterial activity of octyl gallate (OG), an antioxidant food additive, against both Gram-positive and Gram-negative…”
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New Insights into the Biological Functions of Essential TsaB/YeaZ Protein in Staphylococcus aureus by Guo, Haiyong, Lei, Ting, Yang, Junshu, Wang, Yue, Wang, Yifan, Ji, Yinduo

“…TsaB/YeaZ represents a promising target for novel antibacterial agents due to its indispensable role in bacterial survival, high conservation within bacterial…”
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Identification and Validation of a Novel Antibacterial Compound MZ-01 against Methicillin-Resistant Staphylococcus aureus by Yang, Junshu, Brown, Christopher, Noland, Wayland, Johnson, Timothy J., Ji, Yinduo

“…The discovery of new classes of antibiotics is slow, and it is being greatly outpaced by the development of bacterial resistance. This disparity places us in…”
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Contribution of Coagulase and Its Regulator SaeRS to Lethality of CA-MRSA 923 Bacteremia by Liu, Ying, Gao, Wei, Yang, Junshu, Guo, Haiyong, Zhang, Jiang, Ji, Yinduo

“…Coagulase is a critical factor for distinguishing Staphylococcus aureus and coagulase-negative Staphylococcus. Our previous studies demonstrated that the null…”
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Identification of cbiO Gene Critical for Biofilm Formation by MRSA CFSa36 Strain Isolated from Pediatric Patient with Cystic Fibrosis by Liu, Ying, Yang, Junshu, Ji, Michelle, Phillips, James, Wylam, Mark, Ji, Yinduo

“…The colonization of Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), has a detrimental effect on the respiratory care of pediatric…”
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The SaeRS Two-Component System Controls Survival of Staphylococcus aureus in Human Blood through Regulation of Coagulase by Guo, Haiyong, Hall, Jeffrey W, Yang, Junshu, Ji, Yinduo

“…The SaeRS two-component system plays important roles in regulation of key virulence factors and pathogenicity. In this study, however, we found that the…”
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The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus by Yan, Meiying, Hall, Jeffrey W, Yang, Junshu, Ji, Yinduo

“…Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level,…”
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The Essential Two-Component System YhcSR Is Involved in Regulation of the Nitrate Respiratory Pathway of Staphylococcus aureus by Yan, Meiying, Yu, Chuanxin, Yang, Junshu, Ji, Yinduo

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The essentiality of staphylococcal Gcp is independent of its repression of branched-chain amino acids biosynthesis by Lei, Ting, Yang, Junshu, Zheng, Li, Markowski, Todd, Witthuhn, Bruce A, Ji, Yinduo

“…Our previous studies revealed that the staphylococcal protein Gcp is essential for bacterial growth; however, the essential function of Gcp remains undefined…”
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Identification of single nucleotide polymorphisms associated with hyperproduction of alpha-toxin in Staphylococcus aureus by Liang, Xudong, Hall, Jeffrey W, Yang, Junshu, Yan, Meiying, Doll, Katherine, Bey, Russell, Ji, Yinduo

“…The virulence factor α-toxin (hla) is needed by Staphylococcus aureus in order to cause infections in both animals and humans. Although the complicated…”
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The C-terminal domain of the novel essential protein Gcp is critical for interaction with another essential protein YeaZ of Staphylococcus aureus by Lei, Ting, Liang, Xudong, Yang, Junshu, Yan, Meiying, Zheng, Li, Walcheck, Bruce, Ji, Yinduo

“…Previous studies have demonstrated that the novel protein Gcp is essential for the viability of various bacterial species including Staphylococcus aureus;…”
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Characterization of essential enolase in Staphylococcus aureus by Yu, Xuping, Zheng, Li, Yang, Junshu, Lei, Ting, Ji, Yinduo

“…In this study, we characterized the essentiality of enolase for growth of Staphylococcus aureus in vitro by using a TetR-regulated antisense RNA expression…”
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Identification of a Novel Essential Two-Component Signal Transduction System, YhcSR, in Staphylococcus aureus by JUNSONG SUN, LI ZHENG, LANDWEHR, Christina, JUNSHU YANG, YINDUO JI

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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SATB1 3′‐UTR and lncRNA‐UCA1 competitively bind to miR‐495‐3p and together regulate the proliferation and invasion of gastric cancer by Sun, Li, Liu, Lina, Yang, Junshu, Li, Hai, Zhang, Can

“…High expression of special AT‐rich‐binding protein 1 (SATB1) correlates with the advanced TNM stage and short overall and recurrence‐free survival of gastric…”
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Identification of an essential glycoprotease in Staphylococcus aureus by Zheng, Li, Yang, Junshu, Landwehr, Christina, Fan, Frank, Ji, Yinduo

“…The emergence of multi-drug resistant bacterial pathogens is generating enormous public health concern, and highlights an urgent need for new, alternative…”
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Determining Impact of Growth Phases on Capacity of Staphylococcus aureus to Adhere to and Invade Host Cells by Ji, Nansea, Yang, Junshu, Ji, Yinduo

“…One of the largest concerns in public health is the continual emergence of multidrug-resistant bacterial pathogens. The resistance of bacterial pathogens to…”
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