Search Results - "JUNGHARD, O"
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Development of the GerdQ, a tool for the diagnosis and management of gastro‐oesophageal reflux disease in primary care
Published in Alimentary pharmacology & therapeutics (15-11-2009)“…Summary Background Accurate diagnosis and effective management of gastro‐oesophageal reflux disease (GERD) can be challenging for clinicians and other health…”
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Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study
Published in Gut (01-06-2010)“…The aim of this study was to determine the accuracy of the diagnosis of gastro-oesophageal reflux disease (GORD) by the Reflux Disease Questionnaire (RDQ),…”
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Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial
Published in Gut (01-09-2008)“…With the introduction of laparoscopic antireflux surgery (LARS) for gastro-oesophageal reflux disease (GORD) along with the increasing efficacy of modern…”
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Esomeprazole 20 mg maintains symptom control in endoscopy‐negative gastro‐oesophageal reflux disease: a controlled trial of ‘on‐demand’ therapy for 6 months
Published in Alimentary pharmacology & therapeutics (01-03-2001)“…Background: Most patients with gastro‐oesophageal reflux disease (GERD), regardless of endoscopic status, suffer symptomatic relapse within 6 months of…”
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Gastro‐oesophageal reflux symptoms and health‐related quality of life in the adult general population – the Kalixanda study
Published in Alimentary pharmacology & therapeutics (15-06-2006)“…Summary Background The impact of gastro‐oesophageal reflux symptoms on health‐related quality of life in the general population is poorly characterized. Aim To…”
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Prognostic influence of Barrett’s oesophagus and Helicobacter pylori infection on healing of erosive gastro-oesophageal reflux disease (GORD) and symptom resolution in non-erosive GORD: report from the ProGORD study
Published in Gut (01-06-2005)“…Background: Adequacy of acid suppression is a critical factor influencing healing in gastro-oesophageal reflux disease (GORD). The European prospective study…”
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The Usefulness of a Structured Questionnaire in the Assessment of Symptomatic Gastroesophageal Reflux Disease
Published in Scandinavian journal of gastroenterology (1998)“…Background: The diagnosis of gastroesophageal reflux disease (GERD) rests primarily on recognition of symptom patterns that are classical for reflux disease,…”
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Medical or Surgical Management of GERD Patients with Barrett’s Esophagus: The LOTUS Trial 3-Year Experience
Published in Journal of gastrointestinal surgery (01-10-2008)“…Introduction The long-term management of gastroesophageal reflux in patients with Barrett’s esophagus (BE) is not well supported by an evidence-based…”
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Predictors of treatment response in patients with non‐erosive reflux disease
Published in Alimentary pharmacology & therapeutics (15-07-2006)“…Summary Background Up to 40% of patients with non‐erosive reflux disease (NERD) fail to respond to proton pump inhibitor therapy. Aim To determine useful…”
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Heartburn without Oesophagitis: Efficacy of Omeprazole Therapy and Features Determining Therapeutic Response
Published in Scandinavian journal of gastroenterology (1997)“…Background: Data are limited on the value of effective antisecretory therapy in the relief of heartburn in patients without oesophagitis. Methods: Patients…”
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The role of acid suppression in patients with endoscopy‐negative reflux disease: the effect of treatment with esomeprazole or omeprazole
Published in Alimentary pharmacology & therapeutics (15-08-2004)“…Summary Background : Patients with endoscopy‐negative reflux disease have reflux symptoms, mainly heartburn, but not mucosal breaks characteristic of erosive…”
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A model of healing of Los Angeles grades C and D reflux oesophagitis: is there an optimal time of acid suppression for maximal healing?
Published in Alimentary pharmacology & therapeutics (01-08-2010)“…Aliment Pharmacol Ther 2010; 32: 443–447 Summary Background In patients with Los Angeles (LA) grade C or D oesophagitis, a positive relationship has been…”
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Patterns of gastritis and the effect of eradicating Helicobacter pylori on gastro‐oesophageal reflux disease in Western patients with non‐ulcer dyspepsia
Published in Alimentary pharmacology & therapeutics (01-07-2006)“…Summary Background The effect of Helicobacter pylori eradication on the development of gastro‐oesophageal reflux disease is controversial. Aim To determine the…”
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On demand therapy with omeprazole for the long‐term management of patients with heartburn without oesophagitis—a placebo‐controlled randomized trial
Published in Alimentary pharmacology & therapeutics (01-07-1999)“…Aim : To observe the natural course of gastro‐oesophageal reflux disease (GERD) in patients without oesophagitis following effective symptom relief, and to…”
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Intravenous esomeprazole for prevention of peptic ulcer re‐bleeding: rationale/design of Peptic Ulcer Bleed study
Published in Alimentary pharmacology & therapeutics (01-04-2008)“…Summary Background A limited number of trials have investigated the efficacy of proton pump inhibitors for peptic ulcer bleeding, and some study design issues…”
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Quality of life in patients with heartburn but without esophagitis: effects of treatment with omeprazole
Published in The American journal of gastroenterology (01-07-1999)“…Because improvement in quality of life (QoL) is an important therapeutic goal in patients with heartburn but without esophagitis, the aim of the present study…”
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Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire
Published in Alimentary pharmacology & therapeutics (01-05-2007)“…Summary Background The reflux disease questionnaire (RDQ) is a short, patient‐completed instrument. Aims To investigate the psychometric characteristics of the…”
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Sufficient control of heartburn in endoscopy-negative gastro-oesophageal reflux disease trials
Published in Scandinavian journal of gastroenterology (01-12-2003)Get full text
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The effect of the area under the plasma concentration vs time curve and the maximum plasma concentration of esomeprazole on intragastric pH
Published in European journal of clinical pharmacology (01-10-2002)“…The aim of this study was to create a useful model of the effect of the area under the plasma concentration vs time curve (AUC) and the maximum plasma…”
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Effect of Profound Acid Suppression in Functional Dyspepsia: a Double-Blind, Randomized, Placebo-Controlled Trial
Published in Scandinavian journal of gastroenterology (2002)“…Background: Functional dyspepsia (FD) is defined as persistent or recurrent pain/discomfort centred in the upper abdomen, where no structural explanation for…”
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