Search Results - "JUHL, Kirstine"
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The Cation Efflux Transporter ZnT8 (Slc30A8) Is a Major Autoantigen in Human Type 1 Diabetes
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2007)“…Type 1 diabetes (T1D) results from progressive loss of pancreatic islet mass through autoimmunity targeted at a diverse, yet limited, series of molecules that…”
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2
The dental perspective on osteogenesis imperfecta in a Danish adult population
Published in BMC oral health (24-10-2018)“…To report on dental characteristics and treatment load in Danish adult patients with osteogenesis imperfecta (OI). Oral examination of 73 patients with OI was…”
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Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA
Published in Developmental biology (01-01-2014)“…Specification and maturation of insulin+ cells accompanies a transition in expression of Maf family of transcription factors. In development, MafA is expressed…”
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Bombesin Receptor Subtype-3 (BRS-3) Regulates Glucose-Stimulated Insulin Secretion in Pancreatic Islets across Multiple Species
Published in Endocrinology (Philadelphia) (01-11-2011)“…Bombesin receptor subtype-3 (BRS-3) regulates energy homeostasis, and BRS-3 agonism is being explored as a possible therapy for obesity. Here we study the role…”
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ETS‐family genes in pancreatic development
Published in Developmental dynamics (01-11-2007)“…ETS‐family factors play major roles in development and cancer, notably as critical targets for extra‐cellular signaling pathways, including MAPK‐signaling…”
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Mouse Pancreatic Endocrine Cell Transcriptome Defined in the Embryonic Ngn3-Null Mouse
Published in Diabetes (New York, N.Y.) (01-10-2008)“…Mouse Pancreatic Endocrine Cell Transcriptome Defined in the Embryonic Ngn3 -Null Mouse Kirstine Juhl , Suparna A. Sarkar , Randall Wong , Jan Jensen and John…”
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C16:0 Sulfatide Inhibits Insulin Secretion in Rat β-Cells by Reducing the Sensitivity of KATP Channels to ATP Inhibition
Published in Diabetes (New York, N.Y.) (01-10-2006)“…C16:0 Sulfatide Inhibits Insulin Secretion in Rat β-Cells by Reducing the Sensitivity of K ATP Channels to ATP Inhibition Karsten Buschard 1 , Maria Blomqvist…”
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Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis
Published in Current opinion in organ transplantation (01-02-2010)“…Diabetes results from inadequate functional mass of pancreatic beta-cells and therefore replenishing with new glucose-responsive beta-cells is an important…”
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Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells
Published in Science (American Association for the Advancement of Science) (23-11-2007)“…Inositol pyrophosphates are recognized components of cellular processes that regulate vesicle trafficking, telomere length, and apoptosis. We observed that…”
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Synergizing genomic analysis with biological knowledge to identify and validate novel genes in pancreatic development
Published in Pancreas (01-08-2012)“…This study investigated the utility of advanced computational techniques to large-scale genome-based data to identify novel genes that govern murine pancreatic…”
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Secretory phospholipase A2 is released from pancreatic beta-cells and stimulates insulin secretion via inhibition of ATP-dependent K+ channels
Published in Biochemical and biophysical research communications (17-10-2003)“…The release of sPLA(2) from single mouse pancreatic beta-cells was monitored using a fluorescent substrate of the enzyme incorporated in the outer leaflet of…”
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C16:0 sulfatide inhibits insulin secretion in rat β-cells by reducing the sensitivity of [K.sub.ATP] channels to ATP inhibition
Published in Diabetes (New York, N.Y.) (01-10-2006)“…Sulfatide (3'-sulfo-β-galactosyl ceramide) is a glycosphingolipid present in mammalians in various fatty acid isoforms of which the saturated 16 carbon-atom…”
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Stimulus-secretion coupling in the pancreatic beta-cell
Published in Advances in experimental medicine and biology (2004)Get more information
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Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic [beta] Cells
Published in Science (American Association for the Advancement of Science) (23-11-2007)“…Inositol pyrophosphates are recognized components of cellular processes that regulate vesicle trafficking, telomere length, and apoptosis. We observed that…”
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Secretory phospholipase A 2 is released from pancreatic β-cells and stimulates insulin secretion via inhibition of ATP-dependent K + channels
Published in Biochemical and biophysical research communications (2003)“…The release of sPLA 2 from single mouse pancreatic β-cells was monitored using a fluorescent substrate of the enzyme incorporated in the outer leaflet of the…”
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GeneSpeed Beta Cell: An Online Genomics Data Repository and Analysis Resource Tailored for the Islet Cell Biologist
Published in Experimental diabetes research (01-01-2008)“…Objective. We here describe the development of a freely available online database resource, GeneSpeed Beta Cell, which has been created for the pancreatic…”
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cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells
Published in American journal of physiology: endocrinology and metabolism (01-07-2003)“…Using capacitance measurements, we investigated the effects of intracellularly applied recombinant human cytosolic phospholipase A2 (cPLA2alpha) and its…”
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Phentolamine inhibits exocytosis of glucagon by G i2 protein-dependent activation of calcineurin in rat pancreatic α-cells
Published in The Journal of biological chemistry (12-01-2001)Get full text
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Phentolamine Inhibits Exocytosis of Glucagon by Gi2 Protein-dependent Activation of Calcineurin in Rat Pancreatic α-Cells
Published in The Journal of biological chemistry (12-01-2001)“…Capacitance measurements were used to investigate the molecular mechanisms by which imidazoline compounds inhibit glucagon release in rat pancreatic α-cells…”
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