Search Results - "JUFFERMANS, N. P."

Between-trial heterogeneity in ARDS research by Juschten, J., Tuinman, P. R., Guo, T., Juffermans, N. P., Schultz, M. J., Loer, S. A., Girbes, A. R. J., de Grooth, H. J.

“…Purpose Most randomized controlled trials (RCTs) in patients with acute respiratory distress syndrome (ARDS) revealed indeterminate or conflicting study…”
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Awake prone positioning in nonintubated spontaneous breathing ICU patients with acute hypoxemic respiratory failure (PRONELIFE)-protocol for a randomized clinical trial by Morales-Quinteros, L, Schultz, M J, Serpa-Neto, A, Antonelli, M, Grieco, D L, Roca, O, Juffermans, N P, de Haro, C, de Mendoza, D, Blanch, Ll, Camprubí-Rimblas, M, Gomà, Gemma, Artigas-Raventós, A

“…It is uncertain whether awake prone positioning can prevent intubation for invasive ventilation in spontaneous breathing critically ill patients with acute…”
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Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy by Balvers, K., van Dieren, S., Baksaas‐Aasen, K., Gaarder, C., Brohi, K., Eaglestone, S., Stanworth, S., Johansson, P. I., Ostrowski, S. R., Stensballe, J., Maegele, M., Goslings, J. C., Juffermans, N. P., Bergman, R., Naess, P. A., Kolstadbråten, K. M., Rourke, C., Gall, L., Curry, N., Stürmer, E. K., Schäfer, N., Driessen, A., Orr, A., Schubert, A., Görlinger, K., Harrison, M., Buchanan, J., Char, A., Neble, S., Sayel, H.

“…Background The combined effects of balanced transfusion ratios and use of procoagulant and antifibrinolytic therapies on trauma‐induced exsanguination are not…”
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Mitochondrial oxygen tension in critically ill patients receiving red blood cell transfusions: a multicenter observational cohort study by Baysan, M., Hilderink, B., van Manen, L., Caram-Deelder, C., Mik, E. G., Juffermans, N. P., van der Bom, J. G., Arbous, M. S.

“…Purpose Currently, there is no marker of efficacy of red blood cell (RBC) transfusion. This study describes the impact of RBC transfusion on mitochondrial…”
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Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD) by de Jonge, E, de Wilde, R B P, Juffermans, N P, Oostdijk, E A N, Bernards, A T, van Essen, E H R, Kuijper, E J, Visser, C E, Kesecioglu, J, Bonten, M J M

“…Selective decontamination of the digestive tract (SDD) and selective oropharyngeal decontamination (SOD) reduce colonization with antibiotic-resistant…”
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Interhospital critical care transports: a safe trip indeed by van Lieshout, E. J., Juffermans, N. P., Dongelmans, D. A., de Haan, R. J.

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Induction of a hypometabolic state during critical illness - a new concept in the ICU? by ASLAMI, H, JUFFERMANS, N. P

“…Induced hypothermia after cardiopulmonary resuscitation provides organ protection and is currently considered standard of care in clinical practice. An…”
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Lack of evidence of CD40 ligand involvement in transfusion‐related acute lung injury by Tuinman, P. R., Gerards, M. C., Jongsma, G., Vlaar, A. P., Boon, L., Juffermans, N. P.

“…Summary Activated platelets have been implicated in playing a major role in transfusion‐related acute lung injury (TRALI), as platelets can trigger…”
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The effect of aspirin in transfusion‐related acute lung injury in critically ill patients by Tuinman, P. R., Vlaar, A. P., Binnenkade, J. M., Juffermans, N. P.

“…Summary Aspirin has been found to improve outcomes in an animal model of transfusion‐related acute lung injury. We examined the association of aspirin use…”
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Mechanical ventilation aggravates transfusion-related acute lung injury induced by MHC-I class antibodies by Vlaar, A. P. J., Wolthuis, E. K., Hofstra, J. J., Roelofs, J. J. T. H., Boon, L., Schultz, M. J., Lutter, R., Juffermans, N. P.

“…Purpose Transfusion-related acute lung injury (TRALI) occurs more often in critically ill patients than in a general hospital population, possibly due to the…”
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Transfusion-related acute lung injury: a change of perspective by VLAAR, A. P, SCHULTZ, M. J, JUFFERMANS, N. P

“…Two decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, TRALI has emerged as the…”
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Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients by Dickson, Robert P, Schultz, Marcus J, van der Poll, Tom, Schouten, Laura R, Falkowski, Nicole R, Luth, Jenna E, Sjoding, Michael W, Brown, Christopher A, Chanderraj, Rishi, Huffnagle, Gary B, Bos, Lieuwe D J

“…Recent studies have revealed that, in critically ill patients, lung microbiota are altered and correlate with alveolar inflammation. The clinical significance…”
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Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial by Baksaas-Aasen, K., Gall, L. S., Stensballe, J., Juffermans, N. P., Curry, N., Maegele, M., Brooks, A., Rourke, C., Gillespie, S., Murphy, J., Maroni, R., Vulliamy, P., Henriksen, H. H., Pedersen, K. Holst, Kolstadbraaten, K. M., Wirtz, M. R., Kleinveld, D. J. B., Schäfer, N., Chinna, S., Davenport, R. A., Naess, P. A., Goslings, J. C., Eaglestone, S., Stanworth, S., Johansson, P. I., Gaarder, C., Brohi, K.

“…Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We…”
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Depletion of Alveolar Macrophages Exerts Protective Effects in Pulmonary Tuberculosis in Mice by Leemans, Jaklien C, Juffermans, Nicole P, Florquin, Sandrine, van Rooijen, Nico, Vervoordeldonk, Margriet J, Verbon, Annelies, van Deventer, Sander J. H, van der Poll, Tom

“…Mycobacterium tuberculosis bacilli are intracellular organisms that reside in phagosomes of alveolar macrophages (AMs). To determine the in vivo role of AM…”
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Impact of a vancomycin loading dose on the achievement of target vancomycin exposure in the first 24 h and on the accompanying risk of nephrotoxicity in critically ill patients by Hodiamont, C J, Juffermans, N P, Berends, S E, van Vessem, D J, Hakkens, N, Mathôt, R A A, de Jong, M D, van Hest, R M

“…Abstract Background The advocated pharmacokinetic/pharmacodynamic (PK/PD) target for vancomycin, AUC/MIC ≥ 400 mg·h/L, may not be reached with a conventional…”
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Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy by Müller, M. C. A., Straat, M., Meijers, J. C. M., Klinkspoor, J. H., Jonge, E., Arbous, M. S., Schultz, M. J., Vroom, M. B., Juffermans, N. P.

“…Summary Background Coagulopathy has a high prevalence in critically ill patients. An increased International Normalized Ratio (INR) is a common trigger to…”
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Red and wet by VAN WESTERLOO, D. J, JUFFERMANS, N. P

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A Single Oral Dose of Thalidomide Enhances the Capacity of Lymphocytes to Secrete Gamma Interferon in Healthy Humans by VERBON, A, JUFFERMANS, N. P, SPEELMAN, P, VAN DEVENTER, S. J. H, TEN BERGE, I. J. M, GUCHELAAR, H.-J, VAN DER POLL, T

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Diagnosing acute lung injury in the critically ill: a national survey among critical care physicians by VLAAR, A. P. J., HONSELAAR, W. B., BINNEKADE, J. M., GROENEVELD, A. B., SPRONK, P. E., SCHULTZ, M. J., JUFFERMANS, N. P.

“…Background: Incidence reports on acute lung injury (ALI) vary widely. An insight into the diagnostic preferences of critical care physicians when diagnosing…”
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Mechanical Ventilation and the Titer of Antibodies as Risk Factors for the Development of Transfusion-Related Lung Injury by Vlaar, Alexander P. J., Kuipers, Maria T., Hofstra, J. J., Wolthuis, Esther K., Wieland, C. W., Roelofs, Joris J. T. H., Boon, L., Schultz, Marcus J., Lutter, R., Juffermans, Nicole P.

“…Purpose. Onset of transfusion-related acute lung injury (TRALI) is suggested to be a threshold-event. Data is lacking on the relation between titer of…”
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