Search Results - "JUARRANZ, Y."

Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients by Villanueva-Romero, R., Gutiérrez-Cañas, I., Carrión, M., González-Álvaro, I., Rodríguez-Frade, J. M., Mellado, M., Martínez, C., Gomariz, R. P., Juarranz, Y.

“…Vasoactive Intestinal Peptide (VIP) is an important immunomodulator of CD4 + cells in normal and pathological conditions, which exerts its anti-inflammatory…”
Get full text

Vasoactive intestinal peptide axis is dysfunctional in patients with Graves’ disease by Carrión, M., Ramos-Leví, A. M., Seoane, I. V., Martínez-Hernández, R., Serrano-Somavilla, A., Castro, D., Juarranz, Y., González-Álvaro, I., Gomariz, Rosa P., Marazuela, Mónica

“…Vasoactive intestinal peptide (VIP) is a neuropeptide with potent immunoregulatory properties. Reduced serum VIP levels and alterations in VIP…”
Get full text

VIP-PACAP system in immunity: new insights for multitarget therapy by Gomariz, R P, Juarranz, Y, Abad, C, Arranz, A, Leceta, J, Martinez, C

“…Our research about VIP/PACAP and the immune system goes back to 1990 when our group described the expression of VIP on lymphocytes for the first time. Since…”
Get full text

VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts by Gutiérrez-Cañas, I., Juarranz, Y., Santiago, B., Arranz, A., Martinez, C., Galindo, M., Payá, M., Gomariz, R. P., Pablos, J. L.

“…Objectives. Vasoactive intestinal peptide (VIP) has demonstrated therapeutic effects in arthritis by inhibiting both innate and acquired immune responses. We…”
Get full text

Impact of chondroitin sulfate treatment on immunoregulatory neuropeptides levels in OA patients synovitis by Pérez-García, S, Tio, L, Montañés, F, Benito, P, Juarranz, Y, Gomariz, R.P, Monfort, J

Get full text

Vasoactive intestinal peptide as a healing mediator in Crohn's disease by Arranz, A, Abad, C, Juarranz, Y, Leceta, J, Martinez, C, Gomariz, R P

“…The vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide (VIP/PACAP) system is considered as a paradigm for the use of a…”
Get more information

Regulation of TLR expression, a new perspective for the role of VIP in immunity by Gomariz, R.P., Arranz, A., Juarranz, Y., Gutierrez-Cañas, I., Garcia-Gomez, M., Leceta, J., Martínez, C.

“…The contribution of VIP immune functions to the regulation of homeostasis and health is well known. Modulation of immune responses through new therapeutics is…”
Get full text

VIP and Tolerance Induction in Autoimmunity by ROSIGNOLI, F., TORROBA, M., JUARRANZ, Y., GARCÍA-GÓMEZ, M., MARTINEZ, C., GOMARIZ, R.P., PÉREZ-LEIRÓS, C., LECETA, J.

“…:  Vasoactive intestinal peptide (VIP) is a potent anti‐inflammatory agent with immunoregulatory properties, skewing the immune response to a Th2 pattern of…”
Get full text

VIP Decreases TLR4 Expression Induced by LPS and TNF-α Treatment in Human Synovial Fibroblasts by JUARRANZ, Y., GUTIÉRREZ-CAÑAS, I., ARRANZ, A., MARTÍNEZ, C., ABAD, C., LECETA, J., PABLOS, J.L., GOMARIZ, R.P.

“…:  It has been demonstrated that VIP produces beneficial effects both in a murine model of rheumatoid arthritis and in human rheumatoid synovial fibroblasts…”
Get full text

VIP-PACAP System in Immunity by GOMARIZ, R.P., JUARRANZ, Y., ABAD, C., ARRANZ, A., LECETA, J., MARTINEZ, C.

“…:  Our research about VIP/PACAP and the immune system goes back to 1990 when our group described the expression of VIP on lymphocytes for the first time. Since…”
Get full text

Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis by Juarranz, Yasmina, Abad, Catalina, Martinez, Carmen, Arranz, Alicia, Gutierrez-Cañas, Irene, Rosignoli, Florencia, Gomariz, Rosa P, Leceta, Javier

“…Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology, characterized by the presence of inflammatory synovitis accompanied by destruction of…”
Get full text

Peptides targeting Toll-like receptor signalling pathways for novel immune therapeutics by Gomariz, R P, Gutiérrez-Cañas, I, Arranz, A, Carrión, M, Juarranz, Y, Leceta, J, Martínez, C

“…Toll-like receptors (TLRs) are a family of key proteins that permit mammals to detect microbes and endogenous molecules, which are present in body fluids, cell…”
Get more information

Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP by Gomariz, Rosa P., Arranz, Alicia, Abad, Catalina, Torroba, Marta, Martinez, Carmen, Rosignoli, Florencia, Garcia‐Gómez, Maria, Leceta, Javier, Juarranz, Yasmina

“…Toll‐like receptor 2 (TLR2) and ‐4 mediate signals from a great variety of bacterial gut products, giving the host a panel of microbe‐recognizing receptors…”
Get full text

cDNA array analysis of cytokines, chemokines, and receptors involved in the development of tnbs‐induced colitis: Homeostatic role of VIP by Abad, Catalina, Juarranz, Yasmina, Martinez, Carmen, Arranz, Alicia, Rosignoli, Florencia, García‐Gómez, María, Leceta, Javier, Gomariz, Rosa P

“…Crohn's disease (CD) is a chronic inflammatory pathology of the intestine, characterized by diarrhea and weight loss. A healing effect of vasoactive intestinal…”
Get full text

Immunoregulatory properties of vasoactive intestinal peptide in human T cell subsets: Implications for rheumatoid arthritis by Gutiérrez-Cañas, Irene, Juarranz, Yasmina, Santiago, Begoña, Martínez, Carmen, Gomariz, Rosa P, Pablos, José Luis, Leceta, Javier

“…Abstract Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease whose pathogenesis is not completely understood. Unbalanced Th1/Th2 T-cell…”
Get full text

Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock by Martínez, Carmen, Juarranz, Yasmina, Abad, Catalina, Arranz, Alicia, Miguel, Begoña G., Rosignoli, Florencia, Leceta, Javier, Gomariz, Rosa P.

“…Infections caused by Gram‐negative bacteria constitute one of the major causes of septic shock, which results from the inability of the immune system to limit…”
Get full text

Regulation of TLR expression, a new perspective for the role of VIP in immunity: Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide by GOMARIZ, R. P, ARRANZ, A, JUARRANZ, Y, GUTIERREZ-CANAS, I, GARCIA-GOMEZ, M, LECETA, J, MARTINEZ, C

Get full text