Search Results - "JUARRANZ, M. G"
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Vasoactive intestinal peptide modulates proinflammatory mediator synthesis in osteoarthritic and rheumatoid synovial cells
Published in Rheumatology (Oxford, England) (01-04-2004)“…Objective. Vasoactive intestinal peptide (VIP) has demonstrated beneficial effects in several murine models of immune-mediated inflammation by inhibiting both…”
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Vasoactive intestinal peptide in the immune system: potential therapeutic role in inflammatory and autoimmune diseases
Published in Journal of molecular medicine (Berlin, Germany) (2002)“…Vasoactive intestinal peptide (VIP), a neuropeptide that is produced by lymphoid as well as neural cells, exerts a wide spectrum of immunological functions,…”
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Two Basic Residues of the h-VPAC1 Receptor Second Transmembrane Helix Are Essential for Ligand Binding and Signal Transduction
Published in The Journal of biological chemistry (12-01-2001)“…We mutated the vasoactive intestinal peptide (VIP) Asp3 residue and two VPAC1receptor second transmembrane helix basic residues (Arg188and Lys195). VIP had a…”
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Receptors for pituitary adenylate cyclase-activating peptide in human liver
Published in The journal of clinical endocrinology and metabolism (01-08-1995)“…The presence as well as the pharmacological, molecular, and functional properties of pituitary adenylate cyclase-activating peptide (PACAP) receptors have been…”
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Different Domains of the VIP Receptors Modulate Agonist Affinity and Intrinsic Activity
Published in Annals of the New York Academy of Sciences (01-01-2000)Get full text
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Anti-Inflammatory Role in Septic Shock of Pituitary Adenylate Cyclase-Activating Polypeptide Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (22-01-2002)“…Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two mediators synthesized by immune cells, specially…”
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Vasoactive intestinal peptide receptors in rat liver after partial hepatectomy
Published in Biochemical journal (15-07-1992)“…We describe the status of vasoactive intestinal peptide (VIP) receptors in regenerating liver. VIP-stimulated adenylate cyclase activity was markedly decreased…”
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Dopamine enhances somatostatin receptor-mediated inhibition of adenylate cyclase in rat striatum and hippocampus
Published in Journal of neuroscience research (01-05-1997)“…Although there is evidence that suggests that dopamine (DA) has stimulatory effects on somatostatinergic transmission, it is unknown to date if DA increases…”
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Effects of Chronic Ethanol Ingestion on the Vasoactive Intestinal Peptide Receptor-Effector System From Rat Seminal Vesicle Membranes
Published in Alcoholism, clinical and experimental research (01-02-1999)“…We studied the modifications of the vasoactive intestinal peptide (VIP) receptor/effector system from the rat seminal vesicle after chronic ethanol ingestion…”
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Analysis of vasoactive intestinal peptide receptors and the G protein regulation of adenylyl cyclase in seminal vesicle membranes from streptozotocin-diabetic rats
Published in Cellular signalling (01-02-1994)“…The present report describes the status of the vasoactive intestinal peptide (VIP) receptor/effector system of signal transduction in seminal vesicle from…”
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G-protein regulation of adenylate cyclase activity in rat prostatic membranes after chronic ethanol ingestion
Published in The Prostate (01-09-1998)“…BACKGROUND The possibility that long‐term ethanol ingestion might alter either vasoactive intestinal peptide (VIP) content, VIP binding to membrane receptors,…”
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Stimulation of the adenylyl cyclase activity in human endometrial membranes by VIP and related peptides
Published in Bioscience reports (01-04-1993)“…Vasoactive intestinal peptide (VIP) has been shown to stimulate adenylyl cyclase activity in human endometrial membranes. The effect was dependent on the time…”
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Proline residue 280 in the second extracellular loop (EC2) of the VPAC2 receptor is essential for the receptor structure
Published in Peptides (New York, N.Y. : 1980) (01-09-2001)“…Inspection of the amino acid sequence of the human VPAC1 and the VPAC2 receptors after alignment of the conserved residues indicates that the second…”
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Different vasoactive intestinal polypeptide receptor domains are involved in the selective recognition of two VPAC(2)-selective ligands
Published in Molecular pharmacology (01-12-1999)“…A vasoactive intestinal polypeptide (VIP) analog, acylated on the amino-terminal histidine by hexanoic acid (C(6)-VIP), behaved as a VPAC(2) preferring agonist…”
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Neuroendocrine differentiation of the LNCaP prostate cancer cell line maintains the expression and function of VIP and PACAP receptors
Published in Cellular signalling (01-12-2001)“…The molecular mechanisms involved in differentiation of prostate cancer cells to a neuroendocrine (NE) cell phenotype are not well understood. Here we used the…”
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Vasoactive intestinal polypeptide receptor VPAC(1) subtype is predominant in rat prostate membranes
Published in The Prostate (15-09-1999)“…The 28-amino-acid neuropeptide vasoactive intestinal peptide (VIP) might play an important role in the physiology of the prostate, since it stimulates…”
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Expression of vasoactive intestinal peptide (VIP) receptors in human uterus
Published in Peptides (New York, N.Y. : 1980) (01-09-2000)“…We show the existence of functional vasoactive intestinal peptide (VIP) receptors in normal human female genital tract (endometrium, myometrium, ovary and…”
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Characterization of a novel VPAC(1) selective agonist and identification of the receptor domains implicated in the carboxyl-terminal peptide recognition
Published in British journal of pharmacology (01-06-2000)“…Vasoactive Intestinal Polypeptide (VIP) interacts with a high affinity to two subclasses of G protein coupled receptors named VPAC(1) and VPAC(2), and has a 3…”
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Vasoactive intestinal peptide (VIP) stimulates rat prostatic epithelial cell proliferation
Published in The Prostate (01-06-2001)“…BACKGROUND Androgens play a major role in supporting normal growth and functional maintenance in the prostate. However, this gland contains an array of…”
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