Search Results - "JOUNG, Hosouk"

2-D08 treatment regulates C2C12 myoblast proliferation and differentiation via the Erk1/2 and proteasome signaling pathways by Liu, Hyunju, Lee, Su-Mi, Joung, Hosouk

“…SUMOylation is one of the post-translational modifications that involves the covalent attachment of the small ubiquitin-like modifier (SUMO) to the substrate…”
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SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation by Kwon, Duk-Hwa, Kang, Joo-Young, Joung, Hosouk, Kim, Ji-Young, Jeong, Anna, Min, Hyun-Ki, Shin, Sera, Lee, Yun-Gyeong, Kim, Young-Kook, Seo, Sang-Beom, Kook, Hyun

“…The demethylation of histone lysine residues, one of the most important modifications in transcriptional regulation, is associated with various physiological…”
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MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification by Kwon, Duk-Hwa, Eom, Gwang Hyeon, Ko, Jeong Hyeon, Shin, Sera, Joung, Hosouk, Choe, Nakwon, Nam, Yoon Seok, Min, Hyun-Ki, Kook, Taewon, Yoon, Somy, Kang, Wanseok, Kim, Yong Sook, Kim, Hyung Seok, Choi, Hyuck, Koh, Jeong-Tae, Kim, Nacksung, Ahn, Youngkeun, Cho, Hyun-Jai, Lee, In-Kyu, Park, Dong Ho, Suk, Kyoungho, Seo, Sang Beom, Wissing, Erin R., Mendrysa, Susan M., Nam, Kwang-Il, Kook, Hyun

“…Vascular calcification (VC) is often associated with cardiovascular and metabolic diseases. However, the molecular mechanisms linking VC to these diseases have…”
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Inhibition of heat shock protein 70 blocks the development of cardiac hypertrophy by modulating the phosphorylation of histone deacetylase 2 by Yoon, Somy, Kim, Mira, Min, Hyun-Ki, Lee, Yeong-Un, Kwon, Duk-Hwa, Lee, Miyoung, Lee, Sumin, Kook, Taewon, Joung, Hosouk, Nam, Kwang-Il, Ahn, Youngkeun, Kim, Young-Kook, Kim, Jaetaek, Park, Woo Jin, McMullen, Julie R, Eom, Gwang Hyeon, Kook, Hyun

“…Abstract Aims Previously, we reported that phosphorylation of histone deacetylase 2 (HDAC2) and the resulting activation causes cardiac hypertrophy. Through…”
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The microRNA miR‐134‐5p induces calcium deposition by inhibiting histone deacetylase 5 in vascular smooth muscle cells by Choe, Nakwon, Shin, Sera, Joung, Hosouk, Ryu, Juhee, Kim, Young‐Kook, Ahn, Youngkeun, Kook, Hyun, Kwon, Duk‐Hwa

“…Calcium deposition in vascular smooth muscle cells (VSMCs) is a form of ectopic ossification in blood vessels. It can result in rigidity of the vasculature and…”
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miR-27a-3p Targets ATF3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells by Choe, Nakwon, Kwon, Duk-Hwa, Ryu, Juhee, Shin, Sera, Cho, Hye Jung, Joung, Hosouk, Eom, Gwang Hyeon, Ahn, Youngkeun, Park, Woo Jin, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun

“…Vascular calcification, the ectopic deposition of calcium in blood vessels, develops in association with various metabolic diseases and atherosclerosis and is…”
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Casein Kinase-2α1 Induces Hypertrophic Response by Phosphorylation of Histone Deacetylase 2 S394 and its Activation in the Heart by HYEON EOM, Gwang, YOUNG KUK CHO, KOOK, Hyun, KO, Jeong-Hyeon, SHIN, Sera, CHOE, Nakwon, KIM, Yoojung, JOUNG, Hosouk, KIM, Hyung-Seok, NAM, Kwang-Il, HAE JIN KEE

“…Cardiac hypertrophy is characterized by transcriptional reprogramming of fetal gene expression, and histone deacetylases (HDACs) are tightly linked to the…”
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Activation of Histone Deacetylase 2 by Inducible Heat Shock Protein 70 in Cardiac Hypertrophy by HAE JIN KEE, GWANG HYEON EOM, KYUNG KEUN KIM, SEO, Jeong-Sun, KOOK, Hyun, JOUNG, Hosouk, SHIN, Sera, KIM, Ju-Ryoung, YOUNG KUK CHO, CHOE, Nakwon, SIM, Bo-Woong, JO, Daewoong, MYUNG HO JEONG

“…Diverse cardiac diseases induce cardiac hypertrophy, which leads to dilatation and heart failure. We previously reported that hypertrophy can be blocked by…”
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PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart by Yoon, Somy, Kook, Taewon, Min, Hyun-Ki, Kwon, Duk-Hwa, Cho, Young Kuk, Kim, Mira, Shin, Sera, Joung, Hosouk, Jeong, Seung Hoon, Lee, Sumin, Kang, Gaeun, Park, Yunchul, Kim, Yong Sook, Ahn, Youngkeun, McMullen, Julie R., Gergs, Ulrich, Neumann, Joachim, Kim, Kyung Keun, Kim, Jungchul, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun, Eom, Gwang Hyeon

“…Cardiac hypertrophy occurs in response to increased hemodynamic demand and can progress to heart failure. Identifying the key regulators of this process is…”
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Author Correction: PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart by Yoon, Somy, Kook, Taewon, Min, Hyun-Ki, Kwon, Duk-Hwa, Cho, Young Kuk, Kim, Mira, Shin, Sera, Joung, Hosouk, Jeong, Seung Hoon, Lee, Sumin, Kang, Gaeun, Park, Yunchul, Kim, Yong Sook, Ahn, Youngkeun, McMullen, Julie R., Gergs, Ulrich, Neumann, Joachim, Kim, Kyung Keun, Kim, Jungchul, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun, Eom, Gwang Hyeon

“…After the publication of this article, the authors noticed an error in one of the grant numbers (2015R1A2A1A05001708) in the Acknowledgements section…”
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Enhancer of Polycomb1 Acts on Serum Response Factor to Regulate Skeletal Muscle Differentiation by Kim, Ju-Ryoung, Kee, Hae Jin, Kim, Ji-Young, Joung, Hosouk, Nam, Kwang-Il, Eom, Gwang Hyeon, Choe, Nakwon, Kim, Hyung-Suk, Kim, Jeong Chul, Kook, Hoon, Seo, Sang Beom, Kook, Hyun

“…Skeletal muscle differentiation is well regulated by a series of transcription factors. We reported previously that enhancer of polycomb1 (Epc1), a chromatin…”
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2‑D08 mediates notable anticancer effects through multiple cellular pathways in uterine leiomyosarcoma cells by Joung, Hosouk, Liu, Hyunju

“…2',3',4'‑trihydroxyflavone (2‑D08), a SUMO E2 inhibitor, has several biological functions, including anticancer activity, but its effects on uterine…”
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Ginkgolic acid regulates myogenic development by influencing the proliferation and differentiation of C2C12 myoblast cells by Liu, Hyunju, Joung, Hosouk

“…Ginkgolic acid (GA), isolated from the leaves and seed coats of , exerts several biological effects, including antitumor, antibacterial, anti‑HIV and…”
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Abstract 939: Mdm2 Induces Vascular Calcification Through Its E3 Ligase Activity by Kook, Hyun, Kwon, Duk-Hwa, Choe, Nakwon, Shin, Sera, Joung, Hosouk, Ryu, Juhee, Kim, Young-Kuk

“…Abstract only Rationale: Calcium deposition to the vascular smooth muscle matrix, or vascular calcification (VC), makes vessels rigid, increasing morbidity and…”
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Abstract 391: Mir-A-3p Targets Atf3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells by CHOE, Nakwon, Kwon, Duk-hwa, Ryu, Juhee, SHIN, SERA, Joung, Hosouk, Ahn, Youngkeun, Kim, Young-Kook, Kook, Hyun

“…Abstract only Vascular calcification, the ectopic deposition of calcium in blood vessels, develops in association with various metabolic diseases and…”
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Abstract 296: The MicroRNA -134-5p Induces Calcium Deposition by Inhibiting Hdac5 in Vascular Smooth Muscle Cells by Choe, Nakwon, SHIN, SERA, Joung, Hosouk, Ryu, Juhee, Kim, Young-Kook, Ahn, Youngkeun, Kwon, Duk-hwa, Kook, Hyun

“…Abstract only Calcium deposition in vascular smooth muscle cells (VSMCs) is a form of ectopic ossification in blood vessels. It can result in rigidity of the…”
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Sulforaphane inhibits restenosis by suppressing inflammation and the proliferation of vascular smooth muscle cells by Kwon, Jin-Sook, Joung, Hosouk, Kim, Yong Sook, Shim, Young-Sun, Ahn, Youngkeun, Jeong, Myung Ho, Kee, Hae Jin

“…Abstract Objective Sulforaphane, a naturally occurring organosulfur compound in broccoli, has chemopreventive properties in cancer. However, the effects of…”
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Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis by Joung, Hosouk, Kwon, Sehee, Kim, Kyoung-Hoon, Lee, Yun-Gyeong, Shin, Sera, Kwon, Duk-Hwa, Lee, Yeong-Un, Kook, Taewon, Choe, Nakwon, Kim, Jeong Chul, Kim, Young-Kook, Eom, Gwang Hyeon, Kook, Hyun

“…Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the…”
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Abstract 418: Mdm2 E3 Ligase-mediated Ubiquitination of Histone Deacetylase 1 in Vascular Calcification by Kook, Hyun, Kwon, Duk-Hwa, Eom, Gwang Hyeon, Shin, Sera, Joung, Hosouk, Choe, Nakwon, Nam, Yoon Seok, Kook, Taewon, Kim, Hyung Seok, Kim, Yong Sook, Koh, Jeong-Tae, Kim, Nacksung, Nam, Kwang Il

“…Abstract only Vascular calcification (VC) often associates with many cardiovascular and metabolic diseases. Although VC is the cause of high morbidity and…”
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Ret finger protein mediates Pax7-induced ubiquitination of MyoD in skeletal muscle atrophy by Joung, Hosouk, Eom, Gwang Hyeon, Choe, Nakwon, Lee, Hye Mi, Ko, Jeong-Hyeon, Kwon, Duk-Hwa, Nam, Yoon Seok, Min, Hyunki, Shin, Sera, Kook, Jeewon, Cho, Young Kuk, Kim, Jeong Chul, Seo, Sang Beom, Baik, Yung Hong, Nam, Kwang-Il, Kook, Hyun

“…Skeletal muscle atrophy results from the net loss of muscular proteins and organelles and is caused by pathologic conditions such as nerve injury,…”
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