Search Results - "JOST, Daniel"

Epigenomics in 3D: importance of long-range spreading and specific interactions in epigenomic maintenance by Jost, Daniel, Vaillant, Cédric

“…Abstract Recent progresses of genome-wide chromatin conformation capture techniques have shown that the genome is segmented into hierarchically organized…”
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Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains by Jost, Daniel, Carrivain, Pascal, Cavalli, Giacomo, Vaillant, Cédric

“…Genomes of eukaryotes are partitioned into domains of functionally distinct chromatin states. These domains are stably inherited across many cell generations…”
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Prehospital pulse oximetry: a red flag for early detection of silent hypoxemia in COVID-19 patients by Jouffroy, Romain, Jost, Daniel, Prunet, Bertrand

“…Without a systematic SpO2i measurement, a normal breathing rate could mask profound hypoxia and make severity assessment in COVID-19 patients all the more…”
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Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study by Marijon, Eloi, Karam, Nicole, Jost, Daniel, Perrot, David, Frattini, Benoit, Derkenne, Clément, Sharifzadehgan, Ardalan, Waldmann, Victor, Beganton, Frankie, Narayanan, Kumar, Lafont, Antoine, Bougouin, Wulfran, Jouven, Xavier

“…Although mortality due to COVID-19 is, for the most part, robustly tracked, its indirect effect at the population level through lockdown, lifestyle changes,…”
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How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes by Ghosh, Surya K, Jost, Daniel

“…The 3D organization of chromosomes is crucial for regulating gene expression and cell function. Many experimental and polymer modeling efforts are dedicated to…”
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Transcription regulates the spatio-temporal dynamics of genes through micro-compartmentalization by Salari, Hossein, Fourel, Geneviève, Jost, Daniel

“…Although our understanding of the involvement of heterochromatin architectural factors in shaping nuclear organization is improving, there is still ongoing…”
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Coupling 1D modifications and 3D nuclear organization: data, models and function by Jost, Daniel, Vaillant, Cédric, Meister, Peter

“…Over the past decade, advances in molecular methods have strikingly improved the resolution at which nuclear genome folding can be analyzed. This revealed a…”
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Dynamical modeling of the H3K27 epigenetic landscape in mouse embryonic stem cells by Newar, Kapil, Abdulla, Amith Zafal, Salari, Hossein, Fanchon, Eric, Jost, Daniel

“…The Polycomb system via the methylation of the lysine 27 of histone H3 (H3K27) plays central roles in the silencing of many lineage-specific genes during…”
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Bolus intravenous potassium chloride for recurrent ventricular fibrillation by Romain, Jouffroy, Marie, Couetoux Louis, Daniel, Jost, Stéphane, Travers

“…We report the feasibility and recommend the potential efficacy of a bolus intravenous potassium chloride during out-of-hospital cardiac arrest with recurrent…”
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Bosons vs. Fermions – A computational complexity perspective by Brod, Daniel Jost

“…Recent years have seen a flurry of activity in the fields of quantum computing and quantum complexity theory, which aim to understand the computational…”
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Characteristics and clinical assessment of unexplained sudden cardiac arrest in the real-world setting: focus on idiopathic ventricular fibrillation by Waldmann, Victor, Bougouin, Wulfran, Karam, Nicole, Dumas, Florence, Sharifzadehgan, Ardalan, Gandjbakhch, Estelle, Algalarrondo, Vincent, Narayanan, Kumar, Zhao, Alexandre, Amet, Denis, Jost, Daniel, Geri, Guillaume, Lamhaut, Lionel, Beganton, Frankie, Ludes, Bertrand, Bruneval, Patrick, Plu, Isabelle, Hidden-Lucet, Françoise, Albuisson, Juliette, Lavergne, Thomas, Piot, Olivier, Alonso, Christine, Leenhardt, Antoine, Lellouche, Nicolas, Extramiana, Fabrice, Cariou, Alain, Jouven, Xavier, Marijon, Eloi

“…Abstract Aims Recent studies have shown that in more than half of apparently unexplained sudden cardiac arrests (SCA), a specific aetiology can be unmasked by…”
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Transcription induces context-dependent remodeling of chromatin architecture during differentiation by Chahar, Sanjay, Ben Zouari, Yousra, Salari, Hossein, Kobi, Dominique, Maroquenne, Manon, Erb, Cathie, Molitor, Anne M, Mossler, Audrey, Karasu, Nezih, Jost, Daniel, Sexton, Tom

“…Metazoan chromosomes are organized into discrete spatial domains (TADs), believed to contribute to the regulation of transcriptional programs. Despite…”
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DNA Replication and Polymer Chain Duplication Reshape the Genome in Space and Time by D’Asaro, Dario, Tortora, Maxime M. C., Vaillant, Cédric, Arbona, Jean-Michel, Jost, Daniel

“…In eukaryotes, DNA replication constitutes a complex process whereby multiple origins are stochastically fired, and from which the replication machinery…”
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Global chromatin conformation differences in the Drosophila dosage compensated chromosome X by Pal, Koustav, Forcato, Mattia, Jost, Daniel, Sexton, Thomas, Vaillant, Cédric, Salviato, Elisa, Mazza, Emilia Maria Cristina, Lugli, Enrico, Cavalli, Giacomo, Ferrari, Francesco

“…In Drosophila melanogaster the single male chromosome X undergoes an average twofold transcriptional upregulation for balancing the transcriptional output…”
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Psychological, cognitive, and physiological impact of hazards casualties' trainings on first responders: the example of a chemical and radiological training. An exploratory study by Giaume, Louise, Le Roy, Barbara, Daniel, Yann, Lauga Cami, Heloise, Jost, Daniel, Travers, Stéphane, Trousselard, Marion

“…First responders are among the first to respond to hazards casualties. They might operate in volatile, uncertain, complex, and ambiguous (VUCA) environments…”
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Classical simulation of linear optics subject to nonuniform losses by Brod, Daniel Jost, Oszmaniec, Michał

“…We present a comprehensive study of the impact of non-uniform, i.e. path-dependent, photonic losses on the computational complexity of linear-optical…”
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Biophysical ordering transitions underlie genome 3D re-organization during cricket spermiogenesis by Orsi, Guillermo A., Tortora, Maxime M. C., Horard, Béatrice, Baas, Dominique, Kleman, Jean-Philippe, Bucevičius, Jonas, Lukinavičius, Gražvydas, Jost, Daniel, Loppin, Benjamin

“…Spermiogenesis is a radical process of differentiation whereby sperm cells acquire a compact and specialized morphology to cope with the constraints of sexual…”
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PenDA, a rank-based method for personalized differential analysis: Application to lung cancer by Richard, Magali, Decamps, Clémentine, Chuffart, Florent, Brambilla, Elisabeth, Rousseaux, Sophie, Khochbin, Saadi, Jost, Daniel

“…The hopes of precision medicine rely on our capacity to measure various high-throughput genomic information of a patient and to integrate them for personalized…”
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Bifurcation in epigenetics: implications in development, proliferation, and diseases by Jost, Daniel

“…Cells often exhibit different and stable phenotypes from the same DNA sequence. Robustness and plasticity of such cellular states are controlled by diverse…”
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Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans by Sharma, Rahul, Jost, Daniel, Kind, Jop, Gómez-Saldivar, Georgina, van Steensel, Bas, Askjaer, Peter, Vaillant, Cédric, Meister, Peter

“…The adjustment of X-linked gene expression to the X chromosome copy number (dosage compensation [DC]) has been widely studied as a model of chromosome-wide…”
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