Search Results - "JORDAN, Joaquin"
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Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
Published in Cell death and differentiation (01-03-2018)“…Neurodegenerative diseases are a spectrum of chronic, debilitating disorders characterised by the progressive degeneration and death of neurons. Mitochondrial…”
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Acute Bacterial Skin and Skin-Structure Infections, efficacy of Dalbavancin: a systematic review and meta-analysis
Published in Expert review of anti-infective therapy (02-11-2022)“…To know the efficacy of different doses of dalbavancin in acute bacterial skin and skin-structure infections (ABSSSIs) and versus other antibiotics. We…”
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3
On the mechanism underlying ethanol-induced mitochondrial dynamic disruption and autophagy response
Published in Biochimica et biophysica acta (01-07-2015)“…We have explored the mechanisms underlying ethanol-induced mitochondrial dynamics disruption and mitophagy. Ethanol increases mitochondrial fission in a…”
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Characterization of mitophagy in the 6-hydoxydopamine Parkinson's disease model
Published in Toxicological sciences (01-10-2012)“…In the present study, the activation of autophagy and its interaction with the mitochondrial fission machinery was investigated in an experimental model of…”
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6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells
Published in Free radical biology & medicine (01-06-2008)“…Mitochondrial alterations have been associated with the cytotoxic effect of 6-hydroxydopamine (6-OHDA), a widely used neurotoxin to study Parkinson's disease…”
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Numerical study of an unsteady free convective magnetohydrodynamic flow of a dissipative fluid along a vertical plate subject to a constant heat flux
Published in International journal of engineering science (01-11-2006)“…A new method is presented to solve the transient free convection MHD flow of a dissipative fluid along a semi-infinite vertical plate with mass transfer, the…”
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7
Rotenone Induces the Formation of 4-Hydroxynonenal Aggresomes. Role of ROS-Mediated Tubulin Hyperacetylation and Autophagic Flux Disruption
Published in Molecular neurobiology (01-11-2016)“…Oxidative stress causes cellular damage by (i) altering protein stability, (ii) impairing organelle function, or (iii) triggering the formation of 4-HNE…”
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8
Inflammation as therapeutic objective in stroke
Published in Current pharmaceutical design (01-11-2008)“…Ischemic stroke is the most frequent cause of persistent neurologic disability in modern Western societies. Albeit it is still not clear whether inflammation…”
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Network simulation method applied to radiation and viscous dissipation effects on MHD unsteady free convection over vertical porous plate
Published in Applied mathematical modelling (01-09-2007)“…The effects of thermal radiation and viscous dissipation on magneto-hydrodynamic (MHD) unsteady free-convection flow over a semi-infinite vertical porous plate…”
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10
A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles
Published in Molecules (Basel, Switzerland) (19-02-2021)“…Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the…”
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Anxiolytic-like effects and mechanism of (−)-myrtenol: A monoterpene alcohol
Published in Neuroscience letters (05-09-2014)“…•(−)-Myrtenol presents anxiolytic-like action.•The mechanism of action of (−)-myrtenol proposing an interaction with the GABA receptor.•The anxiolytic-like…”
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12
Vitamin D Receptor Polymorphisms in a Spanish Cohort of Parkinson's Disease Patients
Published in Genetic testing and molecular biomarkers (01-02-2024)“…Vitamin D receptor (VDR) is a nuclear hormone receptor widely expressed in the substantia nigra. Its association with an increased risk of Parkinson's disease…”
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13
Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-06-2015)“…The senescence-accelerated mouse-prone 8 (SAMP8), used as a model of aging, displays many established pathological features of Alzheimer's disease. Cognitive…”
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Minocycline mediated mitochondrial cytoprotection: premises for therapy of cerebrovascular and neurodegenerative diseases
Published in Current drug targets (01-01-2013)“…In the last decades, emerging molecular targets for ischemic neuroprotection and regeneration have been postulated. This fact allowed that classical drugs with…”
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Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF
Published in Neurobiology of disease (01-05-2010)“…Abstract In this study we tested whether phosphodiesterase 5 (PDE5) inhibitors, sildenafil and vardenafil, would afford protection against 3-nitropropionic…”
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6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA
Published in Journal of neurochemistry (01-03-2008)“…Mitochondrial alterations have been associated with the cytotoxic effect of 6-hydroxydopamine (6-OHDA), a widely used toxin to study Parkinson's disease. In…”
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17
Network method to study the transient heat transfer problem in a vertical channel with viscous dissipation
Published in International communications in heat and mass transfer (01-11-2006)“…The transient problem for fully developed mixed convection considering the effect of viscous dissipation is investigated for the laminar flow in a…”
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18
Methadone induces necrotic-like cell death in SH-SY5Y cells by an impairment of mitochondrial ATP synthesis
Published in Biochimica et biophysica acta (01-11-2010)“…Methadone is a widely used therapeutic opioid in narcotic addiction and neuropathic pain syndromes. Oncologists regularly use methadone as a long-lasting…”
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Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate
Published in Biochimica et biophysica acta (01-06-2013)“…Phosphodiesterase 5 (PDE5) inhibitors have recently been reported to exert beneficial effects against ischemia–reperfusion injury in several organs but their…”
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Phosphodiesterase 5 inhibitors prevent 3,4-methylenedioxymethamphetamine-induced 5-HT deficits in the rat
Published in Journal of neurochemistry (01-02-2009)“…Phosphodiesterase 5 (PDE5) inhibitors are often used in combination with club drugs such as 3,4-methylenedioxymethamphetamine (MDMA or ecstasy). We…”
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