Search Results - "JONG-IL KIM"

A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease by Baik, Sung Hoon, Kang, Seokjo, Lee, Woochan, Choi, Hayoung, Chung, Sunwoo, Kim, Jong-Il, Mook-Jung, Inhee

“…Reactive microglia are a major pathological feature of Alzheimer's disease (AD). However, the exact role of microglia in AD pathogenesis is still unclear…”
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Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer by Yoo, Seong-Keun, Song, Young Shin, Lee, Eun Kyung, Hwang, Jinha, Kim, Hwan Hee, Jung, Gyeongseo, Kim, Young A, Kim, Su-jin, Cho, Sun Wook, Won, Jae-Kyung, Chung, Eun-Jae, Shin, Jong-Yeon, Lee, Kyu Eun, Kim, Jong-Il, Park, Young Joo, Seo, Jeong-Sun

“…Anaplastic thyroid cancer (ATC) and advanced differentiated thyroid cancers (DTCs) show fatal outcomes, unlike DTCs. Here, we demonstrate mutational landscape…”
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Whole genome sequencing of Nontuberculous Mycobacterium (NTM) isolates from sputum specimens of co-habiting patients with NTM pulmonary disease and NTM isolates from their environment by Yoon, Jung-Ki, Kim, Taek Soo, Kim, Jong-Il, Yim, Jae-Joon

“…Nontuberculous mycobacterium (NTM) species are ubiquitous microorganisms. NTM pulmonary disease (NTM-PD) is thought to be caused not by human-to-human…”
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MicroRNA Expression Profiles in Gastric Carcinogenesis by Hwang, Jinha, Min, Byung-Hoon, Jang, Jiryeon, Kang, So Young, Bae, Hyunsik, Jang, Se Song, Kim, Jong-Il, Kim, Kyoung-Mee

“…Intestinal-type gastric carcinoma exhibits a multistep carcinogenic sequence from adenoma to carcinoma with a gradual increase in genomic alterations. But the…”
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Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease by Lee, Min Young, Lee, Junghee, Hyeon, Seung Jae, Cho, Hyesun, Hwang, Yu Jin, Shin, Jong‐Yeon, McKee, Ann C., Kowall, Neil W., Kim, Jong‐Il, Stein, Thor D., Hwang, Daehee, Ryu, Hoon

“…The pathogenesis of Alzheimer's disease (AD) and the commonest cause of dementia in the elderly remain incompletely understood. Recently, epigenetic…”
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Impact of anesthetic agents on overall and recurrence-free survival in patients undergoing esophageal cancer surgery: A retrospective observational study by Jun, In-Jung, Jo, Jun-Young, Kim, Jong-Il, Chin, Ji-Hyun, Kim, Wook-Jong, Kim, Hyeong Ryul, Lee, Eun-Ho, Choi, In-Cheol

“…Given that surgical stress response and surgical excision may increase the likelihood of post-surgery cancer dissemination and metastasis, the appropriate…”
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A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing by Ju, Young Seok, Lee, Won-Chul, Shin, Jong-Yeon, Lee, Seungbok, Bleazard, Thomas, Won, Jae-Kyung, Kim, Young Tae, Kim, Jong-Il, Kang, Jin-Hyoung, Seo, Jeong-Sun

“…The identification of the molecular events that drive cancer transformation is essential to the development of targeted agents that improve the clinical…”
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Image-based deep learning model using DNA methylation data predicts the origin of cancer of unknown primary by Hwang, Jinha, Lee, Yeajina, Yoo, Seong-Keun, Kim, Jong-Il

“…Cancer of unknown primary (CUP) is a rare type of metastatic cancer in which the origin of the tumor is unknown. Since the treatment strategy for patients with…”
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Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers by Yoo, Seong-Keun, Lee, Seungbok, Kim, Su-Jin, Jee, Hyeon-Gun, Kim, Byoung-Ae, Cho, Hyesun, Song, Young Shin, Cho, Sun Wook, Won, Jae-Kyung, Shin, Jong-Yeon, Park, Do Joon, Kim, Jong-Il, Lee, Kyu Eun, Park, Young Joo, Seo, Jeong-Sun

“…Follicular thyroid carcinoma (FTC) and benign follicular adenoma (FA) are indistinguishable by preoperative diagnosis due to their similar histological…”
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Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy by Kim, Jin Yong, Ohn, Jungyoon, Yoon, Ji-Seon, Kang, Bo Mi, Park, Minji, Kim, Sookyung, Lee, Woochan, Hwang, Sungjoo, Kim, Jong-Il, Kim, Kyu Han, Kwon, Ohsang

“…The maintenance of genetic integrity is critical for stem cells to ensure homeostasis and regeneration. Little is known about how adult stem cells respond to…”
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Tumor Suppressor miRNA-204-5p Regulates Growth, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer by Hong, Bok Sil, Ryu, Han Suk, Kim, Namshin, Kim, Jisun, Lee, Eunshin, Moon, Hyunhye, Kim, Kyoung Hyoun, Jin, Min-Sun, Kwon, Nam Hoon, Kim, Sunghoon, Kim, Donghyun, Chung, Doo Hyun, Jeong, Kyeonghun, Kim, Kwangsoo, Kim, Ki Yoon, Lee, Han-Byoel, Han, Wonshik, Yun, Jihui, Kim, Jong-Il, Noh, Dong-Young, Moon, Hyeong-Gon

“…Various miRNAs play critical roles in the development and progression of solid tumors. In this study, we describe the role of miR-204-5p in limiting growth and…”
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Exploring the role of apolipoprotein E gene promoter polymorphisms in susceptibility to normal-tension glaucoma in a Korean population by Park, Young Jun, Shin, Hye-Young, Kim, Jong-Il

“…Glaucoma, particularly primary open-angle glaucoma (POAG), poses a significant global health concern. Distinguished by intraocular pressure (IOP), POAG…”
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The transcriptional landscape and mutational profile of lung adenocarcinoma by Seo, Jeong-Sun, Ju, Young Seok, Lee, Won-Chul, Shin, Jong-Yeon, Lee, June Koo, Bleazard, Thomas, Lee, Junho, Jung, Yoo Jin, Kim, Jung-Oh, Shin, Jung-Young, Yu, Saet-Byeol, Kim, Jihye, Lee, Eung-Ryoung, Kang, Chang-Hyun, Park, In-Kyu, Rhee, Hwanseok, Lee, Se-Hoon, Kim, Jong-Il, Kang, Jin-Hyoung, Kim, Young Tae

“…All cancers harbor molecular alterations in their genomes. The transcriptional consequences of these somatic mutations have not yet been comprehensively…”
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Genetic Studies of Actinic Keratosis Development: Where Are We Now? by Lee, Young Bok, Kim, Jong-Il

“…Actinic keratosis (AK) is a common precancerous skin lesion that can develop into cutaneous squamous cell carcinoma (CSCC). AK is characterized by atypical…”
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Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts by Na, Deukchae, Chae, Jeesoo, Cho, Sung-Yup, Kang, Wonyoung, Lee, Ahra, Min, Seoyeon, Kang, Jinjoo, Kim, Min Jung, Choi, Jaeyong, Lee, Woochan, Shin, Dongjin, Min, Ahrum, Kim, Yu-Jin, Lee, Kyung-Hun, Kim, Tae-Yong, Suh, Yun-Suhk, Kong, Seong-Ho, Lee, Hyuk-Joon, Kim, Woo-Ho, Park, Hansoo, Im, Seock-Ah, Yang, Han-Kwang, Lee, Charles, Kim, Jong-Il

“…Gastric cancer (GC) is commonly treated by chemotherapy using 5-fluorouracil (5-FU) derivatives and platinum combination, but predictive biomarker remains…”
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Thyroid nodules in childhood‐onset Hashimoto's thyroiditis: Frequency, risk factors, follow‐up course and genetic alterations of thyroid cancer by Lee, Yun Jeong, Cho, Yeon Jin, Heo, You Joung, Chung, Eun‐Jae, Choi, Young Hun, Kim, Jong‐Il, Park, Young Joo, Shin, Choong Ho, Lee, Young Ah

“…Objective We evaluated the frequency, risk factors and the follow‐up outcomes of thyroid nodules, and genetic alterations in thyroid cancer, in youth with…”
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Viral Load Kinetics of MERS Coronavirus Infection by Oh, Myoung-don, Park, Wan Beom, Choe, Pyoeng Gyun, Choi, Su-Jin, Kim, Jong-Il, Chae, Jeesoo, Park, Sung Sup, Kim, Eui-Chong, Oh, Hong Sang, Kim, Eun Jung, Nam, Eun Young, Na, Sun Hee, Kim, Dong Ki, Lee, Sang-Min, Song, Kyoung-Ho, Bang, Ji Hwan, Kim, Eu Suk, Kim, Hong Bin, Park, Sang Won, Kim, Nam Joong

“…Middle East respiratory syndrome coronavirus continues to circulate in the Middle East. During a recent outbreak in Korea, changes in MERS coronavirus viral…”
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Association of Phosphorylated Pyruvate Dehydrogenase with Pyruvate Kinase M2 Promotes PKM2 Stability in Response to Insulin by Hossain, Abu Jubayer, Islam, Rokibul, Seo, Jong-Bok, Park, Hwee-Seon, Kim, Jong-Il, Kumar, Vikas, Lee, Keun Woo, Park, Jae-Bong

“…Insulin is a crucial signalling molecule that primarily functions to reduce blood glucose levels through cellular uptake of glucose. In addition to its role in…”
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High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer by Kim, Jeong Eun, Choi, Jaeyong, Sung, Chang-Ohk, Hong, Yong Sang, Kim, Sun Young, Lee, Hyunjung, Kim, Tae Won, Kim, Jong-Il

“…The global incidence of early-onset colorectal cancer (EO-CRC) is rapidly rising. However, the reason for this rise in incidence as well as the genomic…”
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Identifying Pathogenic Variants of Monogenic Diabetes Using Targeted Panel Sequencing in an East Asian Population by Park, Seung Shin, Jang, Se Song, Ahn, Chang Ho, Kim, Jung Hee, Jung, Hye Seung, Cho, Young Min, Lee, Young Ah, Shin, Choong Ho, Chae, Jong Hee, Kim, Jae Hyun, Choi, Sung Hee, Jang, Hak C, Bae, Jee Cheol, Won, Jong Cheol, Kim, Sung-Hoon, Kim, Jong-Il, Kwak, Soo Heon, Park, Kyong Soo

“…Monogenic diabetes is a specific type of diabetes in which precision medicine could be applied. In this study, we used targeted panel sequencing to investigate…”
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