Search Results - "JONES, T. Hugh"

Testosterone: a metabolic hormone in health and disease by Kelly, Daniel M, Jones, T Hugh

“…Testosterone is a hormone that plays a key role in carbohydrate, fat and protein metabolism. It has been known for some time that testosterone has a major…”
Get full text

European Association of Urology Guidelines on Sexual and Reproductive Health—2021 Update: Male Sexual Dysfunction by Salonia, Andrea, Bettocchi, Carlo, Boeri, Luca, Capogrosso, Paolo, Carvalho, Joana, Cilesiz, Nusret Can, Cocci, Andrea, Corona, Giovanni, Dimitropoulos, Kostantinos, Gül, Murat, Hatzichristodoulou, Georgios, Jones, T. Hugh, Kadioglu, Ates, Martínez Salamanca, Juan Ignatio, Milenkovic, Uros, Modgil, Vaibhav, Russo, Giorgio Ivan, Serefoglu, Ege Can, Tharakan, Tharu, Verze, Paolo, Minhas, Suks

“…The present summary of the European Association of Urology (EAU) guidelines is based on the latest guidelines on male sexual health published in March 2021,…”
Get full text

Testosterone: a vascular hormone in health and disease by Kelly, Daniel M, Jones, T Hugh

“…Coronary heart disease is a leading cause of premature death in men. Epidemiological studies have shown a high prevalence of low serum testosterone levels in…”
Get full text

Testosterone and insulin resistance in the metabolic syndrome and T2DM in men by Rao, Preethi M., Kelly, Daniel M., Jones, T. Hugh

“…This Review discusses the effects of testosterone on risk factors for cardiovascular disease. Particular focus is given to the pathophysiological mechanisms…”
Get full text

Testosterone and mortality by Muraleedharan, Vakkat, Hugh Jones, T.

“…Summary Epidemiological studies have found that men with low or low normal endogenous testosterone are at an increased risk of mortality than those with higher…”
Get full text

Clinical and Biochemical Assessment of Hypogonadism in Men With Type 2 Diabetes: Correlations with bioavailable testosterone and visceral adiposity by Kapoor, Dheeraj, Aldred, Hazel, Clark, Stephanie, Channer, Kevin S, Jones, T. Hugh

“…OBJECTIVE:--The aim of our study was to assess the prevalence of clinical hypogonadism, based on both symptoms and biochemical available measures of…”
Get full text

The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process by Jones, T. Hugh, Saad, Farid

“…Abstract It is becoming increasingly evident that the low serum levels of testosterone experienced by aging men are associated with increased all-cause…”
Get full text

Randomized controlled trials - mechanistic studies of testosterone and the cardiovascular system by Jones, T, Kelly, Daniel

“…Testosterone deficiency is common in men with cardiovascular disease (CVD), and randomized placebo-controlled trials (RCTs) have reported beneficial effects of…”
Get full text

Long-term benefits of testosterone replacement therapy on angina threshold and atheroma in men by Mathur, Atish, Malkin, Christopher, Saeed, Basil, Muthusamy, R, Jones, T Hugh, Channer, Kevin

“…IntroductionIn short-term studies, testosterone replacement therapy has been shown to protect male subjects from exercise-induced ischaemia and modify…”
Get full text

Diagnosis and Treatment of Testosterone Deficiency: Updated Recommendations From the Lisbon 2018 International Consultation for Sexual Medicine by Morgentaler, Abraham, Traish, Abdulmaged, Hackett, Geoffrey, Jones, T. Hugh, Ramasamy, Ranjith

“…The International Consultation for Sexual Medicine met in Lisbon in 2018 to review updated recommendations regarding testosterone deficiency (TD) and its…”
Get full text

Effects of testosterone on Type 2 diabetes and components of the metabolic syndrome by JONES, T. Hugh

“…Observations from clinical studies suggest that low serum levels of testosterone in men are often associated with obesity, insulin resistance, and metabolic…”
Get full text

Testosterone suppresses the expression of regulatory enzymes of fatty acid synthesis and protects against hepatic steatosis in cholesterol-fed androgen deficient mice by Kelly, Daniel M., Nettleship, Joanne E., Akhtar, Samia, Muraleedharan, Vakkat, Sellers, Donna J., Brooke, Jonathan C., McLaren, David S., Channer, Kevin S., Jones, T. Hugh

“…Non-alcoholic fatty liver disease and its precursor hepatic steatosis is common in obesity and type-2 diabetes and is associated with cardiovascular disease…”
Get full text

The Effect of Testosterone Replacement on Endogenous Inflammatory Cytokines and Lipid Profiles in Hypogonadal Men by Malkin, Chris J., Pugh, Peter J., Jones, Richard D., Kapoor, Dheeraj, Channer, Kevin S., Jones, T. Hugh

“…Testosterone has immune-modulating properties, and current in vitro evidence suggests that testosterone may suppress the expression of the proinflammatory…”
Get full text

The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, with Statements for Practice by Hackett, Geoffrey, Kirby, Michael, Rees, Rowland W, Jones, T Hugh, Muneer, Asif, Livingston, Mark, Ossei-Gerning, Nick, David, Janine, Foster, Jeff, Kalra, Philip A, Ramachandran, Sudarshan

“…Testosterone deficiency (TD) is an increasingly common problem with significant health implications, but its diagnosis and management can be challenging. A…”
Get full text

Physiological Testosterone Replacement Therapy Attenuates Fatty Streak Formation and Improves High-Density Lipoprotein Cholesterol in the Tfm Mouse : An Effect That Is Independent of the Classic Androgen Receptor by NETTLESHIP, Joanne E, HUGH JONES, T, CHANNER, Kevin S, JONES, Richard D

“…Research supports a beneficial effect of physiological testosterone on cardiovascular disease. The mechanisms by which testosterone produces these effects have…”
Get full text

Deaths and Cardiovascular Events in Men Receiving Testosterone by Jones, T. Hugh, Channer, Kevin S

Get full text

Statin Therapy Is Associated With Lower Total but Not Bioavailable or Free Testosterone in Men With Type 2 Diabetes by Stanworth, Roger D, Kapoor, Dheeraj, Channer, Kevin S, Jones, T. Hugh

“…OBJECTIVE: There is a high prevalence of hypogonadism in men with type 2 diabetes. This will lead to an increase in assessments of hypogonadism. Statins could…”
Get full text

Testosterone for the aging male; current evidence and recommended practice by Stanworth, Roger D, Jones, T Hugh

“…An international consensus document was recently published and provides guidance on the diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in…”
Get full text

Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes by Muraleedharan, Vakkat, Marsh, Hazel, Kapoor, Dheeraj, Channer, Kevin S, Jones, T Hugh

“…ObjectiveMen with type 2 diabetes are known to have a high prevalence of testosterone deficiency. No long-term data are available regarding testosterone and…”
Get full text

'What should I do with a 60-year old man with a slightly low serum total testosterone concentration and normal levels of serum gonadotrophins'? by Hugh Jones, T.

“…Summary The fundamental question in assessing an older man with a slightly low total testosterone and normal gonadotrophin levels is to determine whether or…”
Get full text