Search Results - "JONES, M. N"

Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail by Wang, Jing, Murphy, Emma J., Nix, Jay C., Jones, David N. M.

“…Aedes aegypti is the primary vector for transmission of Dengue, Zika and chikungunya viruses. Previously it was shown that Dengue virus infection of the…”
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Cold Machine Perfusion Versus Static Cold Storage of Kidneys Donated After Cardiac Death: A UK Multicenter Randomized Controlled Trial by Watson, C. J. E., Wells, A. C., Roberts, R. J., Akoh, J. A., Friend, P. J., Akyol, M., Calder, F. R., Allen, J. E., Jones, M. N., Collett, D., Bradley, J. A.

“…One third of deceased donor kidneys for transplantation in the UK are donated following cardiac death (DCD). Such kidneys have a high rate of delayed graft…”
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Spatiotemporal evolutionary epidemiology of H5N1 highly pathogenic avian influenza in West Africa and Nigeria, 2006–2015 by Ekong, P. S., Fountain‐Jones, N. M., Alkhamis, M. A.

“…Summary H5N1 highly pathogenic avian influenza virus (HPAIV) was first observed in Nigeria in early 2006 and has now spread to more than 17 African countries…”
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Surfactants in membrane solubilisation by Jones, M.N.

“…An understanding of the action of many drugs requires a knowledge of how the drug reaches the site of action in a cell. A detailed knowledge of the structure…”
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A novel mechanism of ligand binding and release in the odorant binding protein 20 from the malaria mosquito Anopheles gambiae by Ziemba, Brian P, Murphy, Emma J, Edlin, Hannah T, Jones, David N M

“…Anopheles gambiae mosquitoes that transmit malaria are attracted to humans by the odor molecules that emanate from skin and sweat. Odorant binding proteins…”
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Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae by Zajdowicz, Sheryl, Haller, Jon C, Krafft, Amy E, Hunsucker, Steve W, Mant, Colin T, Duncan, Mark W, Hodges, Robert S, Jones, David N M, Holmes, Randall K

“…During infection, Corynebacterium diphtheriae must compete with host iron-sequestering mechanisms for iron. C. diphtheriae can acquire iron by a…”
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Validating the SF-36 health survey questionnaire: new outcome measure for primary care by Brazier, J. E., Harper, R., Jones, N. M., O'Cathain, A., Thomas, K. J., Usherwood, T., Westlake, L.

“…OBJECTIVES--To test the acceptability, validity, and reliability of the short form 36 health survey questionnaire (SF-36) and to compare it with the Nottingham…”
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Hypoxic Preconditioning Induces Changes in HIF-1 Target Genes in Neonatal Rat Brain by Jones, Nicole M., Bergeron, Marcelle

“…Hypoxic preconditioning induces tolerance to hypoxic-ischemic injury in neonatal rat brain and is associated with changes in gene expression. Hypoxia-inducible…”
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Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation by Das, Chandrima, Roy, Siddhartha, Namjoshi, Sarita, Malarkey, Christopher S., Jones, David N. M., Kutateladze, Tatiana G., Churchill, Mair E. A., Tyler, Jessica K.

“…The multifunctional Creb-binding protein (CBP) protein plays a pivotal role in many critical cellular processes. Here we demonstrate that the bromodomain of…”
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Discovery and characterization of small molecules that target the GTPase Ral by Yan, Chao, Liu, Degang, Li, Liwei, Wempe, Michael F., Guin, Sunny, Khanna, May, Meier, Jeremy, Hoffman, Brenton, Owens, Charles, Wysoczynski, Christina L., Nitz, Matthew D., Knabe, William E., Ahmed, Mansoor, Brautigan, David L., Paschal, Bryce M., Schwartz, Martin A., Jones, David N. M., Ross, David, Meroueh, Samy O., Theodorescu, Dan

“…Using a structure-based approach, small molecule inhibitors that selectively target the GTPase Ral are identified and characterized; these first-generation…”
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A Progesterone Receptor Co-activator (JDP2) Mediates Activity through Interaction with Residues in the Carboxyl-terminal Extension of the DNA Binding Domain by Hill, Krista K., Roemer, Sarah C., Jones, David N.M., Churchill, Mair E.A., Edwards, Dean P.

“…Progesterone receptor (PR) belongs to the nuclear receptor family of ligand-dependent transcription factors and mediates the major biological effects of…”
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Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility by McLaughlin, John, Lucà, Maria Grazia, Jones, Malcolm N., D'Amato, Massimo, Dockray, Graham J., Thompson, David G.

“…Background & Aims: Fatty acids induce cholecystokinin (CCK) secretion and modify gastric motility, but the chain length requirements for these effects are not…”
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Powered smoke and heat exhaust ventilators: The impact of EN 12101-3 and ISO 21927-3 by Sheard, A.G., Jones, N.M.

“…► EN 12101-3 certified ventilation fans are a European Community legal requirement. ► ISO 21927-3 is an alternative to EN 12101-3 outside the European…”
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Measuring disorganized speech in schizophrenia: automated analysis explains variance in cognitive deficits beyond clinician-rated scales by Minor, K S, Willits, J A, Marggraf, M P, Jones, M N, Lysaker, P H

“…Conveying information cohesively is an essential element of communication that is disrupted in schizophrenia. These disruptions are typically expressed through…”
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Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster by Jones, David N M, Kruse, Schoen W, Zhao, Rui, Smith, Dean P

“…We have solved the high-resolution crystal structures of the Drosophila melanogaster alcohol-binding protein LUSH in complex with a series of short-chain…”
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Factors Linked to Bacterial Vaginosis in Nonpregnant Women by Holzman, Claudia, Leventhal, Judith M, Qiu, Hong, Jones, Nicole M, Wang, Jenny

“…The purposes of this study were to test the hypothesis that vaginal douching is linked to bacterial vaginosis in both symptomatic and asymptomatic women and to…”
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Antiviral treatment following penetrating keratoplasty for herpetic keratitis by Goodfellow, J F B, Nabili, S, Jones, M N A, Nguyen, D Q, Armitage, W J, Cook, S D, Tole, D M

“…Purpose To assess the effect of antiviral treatment on corneal graft survival following penetrating keratoplasty for herpetic keratitis. Methods Retrospective…”
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NMR resonance assignment of the N-terminal GTPase domain of human Miro2 Bound to GTP by Smith, Cassandra E., Jones, David N. M.

“…Miro2 and Miro1 are mitochondrial-associated proteins critical for regulating mitochondrial movement within the cell. Both Miro1 and Miro2 have roles in…”
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Comparison of outcome measures for patients with chronic obstructive pulmonary disease (COPD) in an outpatient setting by Harper, R, Brazier, J E, Waterhouse, J C, Walters, S J, Jones, N M, Howard, P

“…BACKGROUND: To assist clinicians and researchers in choosing outcome measures for patients with chronic obstructive pulmonary disease attending routine…”
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The role of hippocampal estradiol in synaptic plasticity and memory: A systematic review by Finney, C.A., Shvetcov, A., Westbrook, R.F., Jones, N.M., Morris, M.J.

“…•Synaptic plasticity in the hippocampus plays a fundamental role in memory formation.•We examine evidence for estradiol modulating hippocampal plasticity and…”
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