Search Results - "JONES, EMRYS"
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Matrix Assisted Rapid Evaporative Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (06-08-2019)“…Rapid evaporative ionization mass spectrometry (REIMS) is a highly versatile technique allowing the sampling of a range of biological solid or liquid samples…”
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Optimised Desorption Electrospray Ionisation Mass Spectrometry Imaging (DESI-MSI) for the Analysis of Proteins/Peptides Directly from Tissue Sections on a Travelling Wave Ion Mobility Q-ToF
Published in Journal of the American Society for Mass Spectrometry (01-12-2018)“…Desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) is typically known for the ionisation of small molecules such as lipids and…”
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De Novo Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2020)“…The incidence of esophageal adenocarcinoma is rising, survival remains poor, and new tools to improve early diagnosis and precise treatment are needed. Cancer…”
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Faster, More Reproducible DESI-MS for Biological Tissue Imaging
Published in Journal of the American Society for Mass Spectrometry (01-10-2017)“…A new, more robust sprayer for desorption electrospray ionization (DESI) mass spectrometry imaging is presented. The main source of variability in DESI is…”
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DESI Mass Spectrometry Imaging (MSI)
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…Desorption Electrospray Ionization (DESI) mass spectrometry is a technique that allows chemical information to be obtained directly from a wide range of…”
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Characterization and Identification of Clinically Relevant Microorganisms Using Rapid Evaporative Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (01-07-2014)“…Rapid evaporative ionization mass spectrometry (REIMS) was investigated for its suitability as a general identification system for bacteria and fungi. Strains…”
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Multiple statistical analysis techniques corroborate intratumor heterogeneity in imaging mass spectrometry datasets of myxofibrosarcoma
Published in PloS one (29-09-2011)“…MALDI mass spectrometry can generate profiles that contain hundreds of biomolecular ions directly from tissue. Spatially-correlated analysis, MALDI imaging MS,…”
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Rapid Evaporative Ionization Mass Spectrometry Imaging Platform for Direct Mapping from Bulk Tissue and Bacterial Growth Media
Published in Analytical chemistry (Washington) (03-03-2015)“…Rapid evaporative ionization mass spectrometry (REIMS) technology allows real time intraoperative tissue classification and the characterization and…”
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Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)“…Significance Proteins and lipids accumulating in deposits external to the retinal pigment epithelium (RPE) represent a barrier to metabolic exchange between…”
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Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry
Published in Cancer research (Chicago, Ill.) (01-05-2015)“…Breast cancer is a heterogeneous disease characterized by varying responses to therapeutic agents and significant differences in long-term survival. Thus,…”
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Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2014)“…Mass spectrometry imaging (MSI) provides the opportunity to investigate tumor biology from an entirely novel biochemical perspective and could lead to the…”
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The feasibility of a multi‐professional training to improve how health care professionals deliver different news to families during pregnancy and at birth
Published in Child : care, health & development (01-07-2020)“…Background In the United Kingdom, pregnant women are offered foetal anomaly screening to assess the chance of their baby being born with eleven different…”
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Real-Time Screening of Biocatalysts in Live Bacterial Colonies
Published in Journal of the American Chemical Society (01-02-2017)“…Screening of bacterial colonies to identify new biocatalytic activities is a widely adopted tool in biotechnology, but is constrained by the requirements for…”
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Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry
Published in Analytical chemistry (Washington) (20-11-2018)“…Mass spectrometry imaging (MSI) has proven to be a valuable tool for drug and metabolite imaging in pharmaceutical toxicology studies and can reveal, for…”
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Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3×Tg Alzheimer mouse model
Published in Biochimica et biophysica acta. Proteins and proteomics (01-07-2017)“…Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) can simultaneously measure hundreds of biomolecules directly from tissue…”
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Imaging mass spectrometry statistical analysis
Published in Journal of proteomics (30-08-2012)“…Imaging mass spectrometry is increasingly used to identify new candidate biomarkers. This clinical application of imaging mass spectrometry is highly…”
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Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation
Published in Methods (San Diego, Calif.) (15-07-2016)“…[Display omitted] •Poly-sialylated gangliosides are imaged as multiply charged ions using DESI.•Ion mobility separation simplifies DESI MSI data…”
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Analysis of intact bacteria using rapid evaporative ionisation mass spectrometry
Published in Chemical communications (Cambridge, England) (14-07-2013)“…An identification system for microorganisms based on recently developed rapid evaporative ionisation mass spectrometry (REIMS) is presented. Nine bacterial…”
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Lipidomics for translational skin research: A primer for the uninitiated
Published in Experimental dermatology (01-07-2018)“…Healthy skin depends on a unique lipid profile to form a barrier that confers protection and prevents excessive water loss, aids cell‐cell communication and…”
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3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle
Published in Scientific reports (05-10-2020)“…Desorption electrospray ionisation mass spectrometry (DESI-MS) can image hundreds of molecules in a 2D tissue section, making it an ideal tool for mapping…”
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