Search Results - "JONES, DAVID S."

History in a Crisis — Lessons for Covid-19 by Jones, David S

“…The history of human responses to epidemics carries various lessons for our current situation. Two of the more disheartening ones are that stigmatization…”
Get full text

On the Coronavirus (COVID-19) Outbreak and the Smart City Network: Universal Data Sharing Standards Coupled with Artificial Intelligence (AI) to Benefit Urban Health Monitoring and Management by Allam, Zaheer, Jones, David S

“…As the Coronavirus (COVID-19) expands its impact from China, expanding its catchment into surrounding regions and other countries, increased national and…”
Get full text

Unpacking the '15-Minute City' via 6G, IoT, and Digital Twins: Towards a New Narrative for Increasing Urban Efficiency, Resilience, and Sustainability by Allam, Zaheer, Bibri, Simon Elias, Jones, David S, Chabaud, Didier, Moreno, Carlos

“…The '15-minute city' concept is emerging as a potent urban regeneration model in post-pandemic cities, offering new vantage points on liveability and urban…”
Get full text

Getting genetic ancestry right for science and society by Lewis, Anna C F, Molina, Santiago J, Appelbaum, Paul S, Dauda, Bege, Di Rienzo, Anna, Fuentes, Agustin, Fullerton, Stephanie M, Garrison, Nanibaa' A, Ghosh, Nayanika, Hammonds, Evelynn M, Jones, David S, Kenny, Eimear E, Kraft, Peter, Lee, Sandra S-J, Mauro, Madelyn, Novembre, John, Panofsky, Aaron, Sohail, Mashaal, Neale, Benjamin M, Allen, Danielle S

“…We must embrace a multidimensional, continuous view of ancestry and move away from continental ancestry categories…”
Get full text

Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring by Caffarel-Salvador, Ester, Brady, Aaron J, Eltayib, Eyman, Meng, Teng, Alonso-Vicente, Ana, Gonzalez-Vazquez, Patricia, Torrisi, Barbara M, Vicente-Perez, Eva Maria, Mooney, Karen, Jones, David S, Bell, Steven E J, McCoy, Colin P, McCarthy, Helen O, McElnay, James C, Donnelly, Ryan F

“…We describe, for the first time the use of hydrogel-forming microneedle (MN) arrays for minimally-invasive extraction and quantification of drug substances and…”
Get full text

Magnitude and Duration of Late Ordovician-Early Silurian Glaciation by Finnegan, Seth, Bergmann, Kristin, Eiler, John M, Jones, David S, Fike, David A, Eisenman, Ian, Hughes, Nigel C, Tripati, Aradhna K, Fischer, Woodward W

“…Understanding ancient climate changes is hampered by the inability to disentangle trends in ocean temperature from trends in continental ice volume. We used…”
Get full text

Construction of Drug–Polymer Thermodynamic Phase Diagrams Using Flory–Huggins Interaction Theory: Identifying the Relevance of Temperature and Drug Weight Fraction to Phase Separation within Solid Dispersions by Tian, Yiwei, Booth, Jonathan, Meehan, Elizabeth, Jones, David S, Li, Shu, Andrews, Gavin P

“…Amorphous drug–polymer solid dispersions have the potential to enhance the dissolution performance and thus bioavailability of BCS class II drug compounds. The…”
Get full text

Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Feasibility Studies and Physicochemical Characterization by Li, Shu, Yu, Tao, Tian, Yiwei, McCoy, Colin P, Jones, David S, Andrews, Gavin P

“…Engineered cocrystals offer an alternative solid drug form with tailored physicochemical properties. Interestingly, although cocrystals provide many new…”
Get full text

Calibrating the Cryogenian by Macdonald, Francis A, Schmitz, Mark D, Crowley, James L, Roots, Charles F, Jones, David S, Maloof, Adam C, Strauss, Justin V, Cohen, Phoebe A, Johnston, David T, Schrag, Daniel P

“…The Neoproterozoic was an era of great environmental and biological change, but a paucity of direct and precise age constraints on strata from this time has…”
Get full text

Spectroscopic and Thermal Characterisation of Interpenetrating Hydrogel Networks (IHNs) Based on Polymethacrylates and Pluronics, and Their Physicochemical Stability under Aqueous Conditions by Jones, David S, Westwood, Marion, Li, Shu, Andrews, Gavin P

“…This study describes the physicochemical characterisation of interpenetrating hydrogel networks (IHNs) composed of either poly(hydroxyethylmethacrylate,…”
Get full text

Comparative Study of Different Methods for the Prediction of Drug–Polymer Solubility by Knopp, Matthias Manne, Tajber, Lidia, Tian, Yiwei, Olesen, Niels Erik, Jones, David S, Kozyra, Agnieszka, Löbmann, Korbinian, Paluch, Krzysztof, Brennan, Claire Marie, Holm, René, Healy, Anne Marie, Andrews, Gavin P, Rades, Thomas

“…In this study, a comparison of different methods to predict drug–polymer solubility was carried out on binary systems consisting of five model drugs…”
Get full text

Mucoadhesive Polymeric Polyologels Designed for the Treatment of Periodontal and Related Diseases of the Oral Cavity by Andrews, Gavin P, Laverty, Thomas, Jones, David S

“…The study objective was to design and characterise herein unreported polyologels composed of a range of diol and triol solvents and polyvinyl methyl…”
Get full text

Future (post-COVID) digital, smart and sustainable cities in the wake of 6G: Digital twins, immersive realities and new urban economies by Allam, Zaheer, Jones, David S.

“…•Explores the emerging subject of 6G and its associated concepts.•Dwells into the application of 6G in cities and its challenges.•Underlines future prospects…”
Get full text

Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery? by Qian, Kaijie, Stella, Lorenzo, Jones, David S., Andrews, Gavin P., Du, Huachuan, Tian, Yiwei

“…Among many methods to mitigate the solubility limitations of drug compounds, amorphous solid dispersion (ASD) is considered to be one of the most promising…”
Get full text

Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Enhancing Cocrystal Yield by Li, Shu, Yu, Tao, Tian, Yiwei, Lagan, Colette, Jones, David S, Andrews, Gavin P

“…Pharmaceutical cocrystals have attracted increasing attention over the past decade as an alternative way to modify the physicochemical properties and hence…”
Get full text

Insights from full-text analyses of the Journal of the American Medical Association and the New England Journal of Medicine by Abdalla, Moustafa, Abdalla, Mohamed, Abdalla, Salwa, Saad, Mohamed, Jones, David S, Podolsky, Scott H

“…Analysis of the content of medical journals enables us to frame the shifting scientific, material, ethical, and epistemic underpinnings of medicine over time,…”
Get full text

Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity by Scaria, Puthupparampil V, Chen, Beth, Rowe, Christopher G, Jones, David S, Barnafo, Emma, Fischer, Elizabeth R, Anderson, Charles, MacDonald, Nicholas J, Lambert, Lynn, Rausch, Kelly M, Narum, David L, Duffy, Patrick E

“…Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed…”
Get full text

Pandemic stricken cities on lockdown. Where are our planning and design professionals [now, then and into the future]? by Allam, Zaheer, Jones, David S.

“…•Urban resilience must include dimensions of pandemics and health emergencies.•Pandemics impact on the livelihood of urban areas.•The role of urban planning…”
Get full text

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle by Shimp, Richard L, Rowe, Christopher, Reiter, Karine, Chen, Beth, Nguyen, Vu, Aebig, Joan, Rausch, Kelly M, Kumar, Krishan, Wu, Yimin, Jin, Albert J, Jones, David S, Narum, David L

“…Highlights • Pfs25 is candidate for a malaria transmission blocking vaccine. • A recombinant Pfs25 protein was chemically cross-linked to ExoProtein A (EPA). •…”
Get full text

Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms by Vyas, Darshali A, Eisenstein, Leo G, Jones, David S

“…Diagnostic algorithms and practice guidelines that adjust or “correct” their outputs on the basis of a patient’s race or ethnicity guide decisions in ways that…”
Get full text