Search Results - "JONES, D. N. C"

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity by Woolley, M. L., Pemberton, D. J., Bate, S., Corti, C., Jones, D. N. C.

“…Rationale Group II metabotropic glutamate receptors (mGluRs) comprise the mGluR2 and mGluR3 subtypes, the activation and modulation of which has been suggested…”
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Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat by Woolley, M. L., Waters, K. A., Gartlon, J. E., Lacroix, L. P., Jennings, C., Shaughnessy, F., Ong, A., Pemberton, D. J., Harries, M. H., Southam, E., Jones, D. N. C., Dawson, L. A.

“…Rationale Positive allosteric modulators of the glutamatergic α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptor do not stimulate AMPA…”
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Medial prefrontal cortex volume loss in rats with isolation rearing-induced deficits in prepulse inhibition of acoustic startle by Day-Wilson, K.M., Jones, D.N.C., Southam, E., Cilia, J., Totterdell, S.

“…Rearing rats in isolation produces perturbations in behavior and brain neurochemistry suggested to resemble those of schizophrenia. In particular,…”
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Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats : an update by CILIA, J, HATCHER, P. D, REAVILL, C, JONES, D. N. C

“…Rats reared in social isolation from weaning show prepulse inhibition (PPI) deficits which are thought to model the sensorimotor gating deficits seen in…”
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Differential expression of IEG mRNA in rat brain following acute treatment with clozapine or haloperidol: a semi-quantitative RT—PCR study by Robbins, MJ, Critchlow, HM, Lloyd, A., Cilia, J., Clarke, JD, Bond, B., Jones, DNC, Maycox, PR

“…Antipsychotic drugs have been shown to modulate immediate early gene (IEG) expression in rat brain regions that are associated with schizophrenia, which may be…”
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The effects of ziprasidone on regional c-Fos expression in the rat forebrain by JENNINGS, C. A, CLUDERAY, J. E, GARTLON, J, CILIA, J, LLOYD, A, JONES, D. N. C, SOUTHAM, E

“…Typical and atypical antipsychotic drugs produce characteristic patterns of immediate early gene expression in rat forebrain that are considered to reflect…”
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Effect of scopolamine on visual attention in rats by JONES, D. N. C, HIGGINS, G. A

“…In the present study, the effects of scopolamine (SCOP) were determined upon the performance of rats in the five-choice serial reaction time task, a test of…”
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Short-term individual housing induced social deficits in female Mongolian gerbils: Attenuation by chronic but not acute imipramine by Pickles, A.R., Hagan, J.J., Jones, D.N.C., Hendrie, C.A.

“…Mongolian gerbils are highly sensitive to manipulations of their social environments. Housing females individually for short periods (in the order of 7–21…”
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Further neurochemical and behavioural investigation of Brattleboro rats as a putative model of schizophrenia by Cilia, J., Gartlon, JE, Shilliam, C., Dawson, LA, Moore, SH, Jones, DNC

“…Brattleboro (BRAT) rats are a mutant variant of the Long-Evans (LE) strain deficient in the neurohormone vasopressin. BRAT rats show behavioural alterations…”
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The behavioural effects of corticotropin-releasing factor-related peptides in rats by JONES, D. N. C, KORTEKAAS, R, SLADE, P. D, MIDDLEMISS, D. N, HAGAN, J. J

“…The present study determined the behavioural effects of the corticotropin releasing factor (CRF)-related peptides, human/rat CRF (h/rCRF), ovine CRF (oCRF),…”
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Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains by Rogers, Derek C., Jones, Declan N.C., Nelson, Paul R., Jones, C.Matthew, Quilter, Charlotte A., Robinson, Tracey L., Hagan, Jim J.

“…Detailed characterisation of six inbred strains of mice commonly used in transgenic and knockout research was carried out using a battery of behavioural tests…”
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Development of SHIRPA to characterise the phenotype of gene-targeted mice by Hatcher, J.P., Jones, D.N.C., Rogers, D.C., Hatcher, P.D., Reavill, C., Hagan, J.J., Hunter, A.J.

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Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat: Special Issue on Cognitive Enhancers by WOOLLEY, M. L, WATERS, K. A, JONES, D. N. C, DAWSON, L. A, GARTLON, J. E, LACROIX, L. P, JENNINGS, C, SHAUGHNESSY, F, ONG, A, PEMBERTON, D. J, HARRIES, M. H, SOUTHAM, E

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Isolation and Mapping of Escherichia coli K12 Mutants Defective in Phenylacetate Degradation by COOPER, RONALD A, JONES, DAVID C. N, PARROTT, SUZANNE

“…Department of Biochemistry, University of Leicester, University Road, Leicester LE1 7RH, UK ABSTRACT Summary: Mutants of Escherichia coli K12 unable to grow on…”
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Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: acquisition and performance of the DRL-60s test by Bull, Eleanor, Reavill, Charlie, Hagan, Jim J, Overend, Philip, Jones, Declan N.C

“…The spontaneously hypertensive rat (SHR) has been proposed as an animal model of attention deficit hyperactivity disorder (ADHD). It is hyperactive in a…”
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Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats: Special Issue on the Psychopharmacology of Prepulse Inhibition: Basic and Clinic Studies by CILIA, J, REAVILL, C, HAGAN, J. J, JONES, D. N. C

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Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task by Kirkby, Deborah L., Jones, Declan N.C., Higgins, Guy A.

“…The present study compared the influence of prefeeding (0, 10, 20 g or an unlimited amount of food pellets for a 90 min period prior to testing) with the…”
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Influence of peptide CRF receptor antagonists upon the behavioural effects of human/rat CRF by Jones, Declan N.C, Kortekaas, Ruud, Hatcher, Paula D, Middlemiss, Derek N, White, Alan, Hagan, Jim J

“…The effects of the corticotropin-releasing factor (CRF) receptor antagonists, α-helical CRF-(9–41), [ d-Phe 12,Nle 21,38,CαMeLeu 37]humanCRF-(12–41) (…”
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Influence of naloxone upon motor activity induced by psychomotor stimulant drugs by JONES, D. N. C, HOTLZMAN, S. G

“…Naloxone, an opioid receptor antagonist, attenuates a wide range of behavioral effects of d-amphetamine, such as the stimulation of motor activity. To…”
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Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors by Jones, D N, Holtzman, S G

“…Naloxone, the opioid receptor antagonist, attenuates the effects of amphetamine in a wide range of behavioral paradigms. To determine the role of the opioid…”
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