Search Results - "JONES, Barry"

Cytochrome P450 2J2: potential role in drug metabolism and cardiotoxicity by Solanki, Meetal Satishkumar, Pointon, Amy, Jones, Barry C, Herbert, Karl E

“…Drug-induced cardiotoxicity may be modulated by endogenous arachidonic acid (AA) derived metabolites known as epoxyeicosatrienoic acids (EETs) synthesised by…”
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Nano‐LC: An updated review by Shan, Lian, Jones, Barry R.

“…Low‐flow chromatography has a rich history of innovation but has yet to reach widespread implementation in bioanalytical applications. Improvements in pump…”
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Protein Biomarker Quantification by Immunoaffinity Liquid Chromatography-Tandem Mass Spectrometry: Current State and Future Vision by Neubert, Hendrik, Shuford, Christopher M, Olah, Timothy V, Garofolo, Fabio, Schultz, Gary A, Jones, Barry R, Amaravadi, Lakshmi, Laterza, Omar F, Xu, Keyang, Ackermann, Bradley L

“…Immunoaffinity-mass spectrometry (IA-MS) is an emerging analytical genre with several advantages for profiling and determination of protein biomarkers. Because…”
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A hybrid IA-LC-MS/MS method for adrenocorticotropic hormone(1-24) to support interpretation of low-dose cosyntropin-stimulation test by Jones, Barry R, Shao, Junlong, Sanghvi, Mitesh, Ayala, Alejandro, Luo, Rosa, Wang, Jian

“…Adrenocorticotropic hormone 1-24 (ACTH[1-24]) has a similar effect as endogenous ACTH(1-39) to generate cortisol by targeting the MC2R receptor on the adrenal…”
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U.K. household-sector money demand during Brexit and the pandemic by Fleissig, Adrian R., Jones, Barry E.

“…Conventional monetary aggregates assume perfect substitutability between monetary assets. We use monthly household-sector data to estimate two versions of the…”
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An Investigation into the Prediction of in Vivo Clearance for a Range of Flavin-containing Monooxygenase Substrates by Jones, Barry C, Srivastava, Abhishek, Colclough, Nicola, Wilson, Joanne, Reddy, Venkatesh Pilla, Amberntsson, Sara, Li, Danxi

“…Flavin-containing monooxygenases (FMO) are metabolic enzymes mediating the oxygenation of nucleophilic atoms such as nitrogen, sulfur, phosphorus, and…”
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Euro area monetary asset demand and Divisia aggregates by Fleissig, Adrian R., Jones, Barry E., Darvas, Zsolt

“…Monetary asset user costs are functions of spreads between a benchmark rate of return and the own rates of return on the monetary assets. We analyze the impact…”
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Life in the Diaspora: Christian interpretation of Esther in dialogue with Judaism by Jones, Barry A

“…Christian interpretation of Esther has historically been limited by Christian bias against Judaism and by the teaching of Christian supersessionism…”
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Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes by Hendriks, Delilah F.G., Vorrink, Sabine U., Smutny, Tomas, Sim, Sarah C., Nordling, Åsa, Ullah, Shahid, Kumondai, Masaki, Jones, Barry C., Johansson, Inger, Andersson, Tommy B., Lauschke, Volker M., Ingelman‐Sundberg, Magnus

“…Cytochrome P450 (CYP) 3A4 induction is an important cause of drug–drug interactions, making early identification of drug candidates with CYP3A4 induction…”
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Drug metabolite identification using ultrahigh‐performance liquid chromatography–ultraviolet spectroscopy and parallelized scans on a tribrid Orbitrap mass spectrometer by Wilkinson, Stephen D., Martin, Scott, Orton, Alexandra L., Markandu, Roshini, Jones, Barry C.

“…Rationale To capture all metabolites in metabolite identification studies, MS/MS information is required in both positive and negative ionization mode, usually…”
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Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules by Jones, Barry R, Schultz, Gary A, Eckstein, James A, Ackermann, Bradley L

“…Quantitation of biomarkers by LC-MS/MS is complicated by the presence of endogenous analytes. This challenge is most commonly overcome by calibration using an…”
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An Investigation into the Prediction of the Plasma Concentration-Time Profile and Its Interindividual Variability for a Range of Flavin-Containing Monooxygenase Substrates Using a Physiologically Based Pharmacokinetic Modeling Approach by Reddy, Venkatesh Pilla, Jones, Barry C, Colclough, Nicola, Srivastava, Abhishek, Wilson, Joanne, Li, Danxi

“…Our recent paper demonstrated the ability to predict in vivo clearance of flavin-containing monooxygenase (FMO) drug substrates using in vitro human hepatocyte…”
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CYP-Mediated Sulfoximine Deimination of AZD6738 by Jones, Barry C, Markandu, Roshini, Gu, Chungang, Scarfe, Graeme

“…In hepatic S9 and human liver microsomes (HLMs) the sulfoximine moiety of the ATR inhibitor AZD6738 is metabolized to its corresponding sulfoxide (AZ8982) and…”
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Dictionary of World Biography: 3rd Edition by Barry Jones

“…Jones, Barry Owen (1932– ). Australian politician, writer and lawyer, born in Geelong. Educated at Melbourne University, he was a public servant, high school…”
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Managing the Risk of CYP3A Induction in Drug Development: A Strategic Approach by Jones, Barry C, Rollison, Helen, Johansson, Susanne, Kanebratt, Kajsa P, Lambert, Craig, Vishwanathan, Karthick, Andersson, Tommy B

“…Induction of cytochrome P450 (P450) can impact the efficacy and safety of drug molecules upon multiple dosing with coadministered drugs. This strategy is…”
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Dictionary of World Biography: Third Edition by Jones, Barry

“…Jones, Barry Owen (1932– ). Australian politician, writer and lawyer, born in Geelong. Educated at Melbourne University, he was a public servant, high school…”
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A review of expectancy theory and alcohol consumption by Jones, Barry T., Corbin, Will, Fromme, Kim

“…Research is reviewed on the association between alcohol outcome expectancies and consumption which has led many to argue that manipulating expectancies might…”
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LC–MS/MS quantification of asymmetric dimethyl arginine and symmetric dimethyl arginine in plasma using surrogate matrix and derivatization with fluorescamine by Junnotula, Venkatraman, Jones, Barry R, Gorman, Shelby, Shen, Miaoqing, Mulvana, Daniel

“…A novel LC–MS/MS method using a surrogate matrix and derivatization with fluorescamine was developed and validated for simultaneous quantification of…”
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Exploring concepts of in vitro time-dependent CYP inhibition assays by Stresser, David M, Mao, Jialin, Kenny, Jane R, Jones, Barry C, Grime, Kenneth

“…Evaluation of time-dependent inhibition (TDI) properties in drug candidates is generally required for any compound entering development. Methods to evaluate…”
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How Long Does a Face Lift Last? Objective and Subjective Measurements over a 5-Year Period by Jones, Barry M., Lo, Steven J.

“…The longevity of face-lift surgery is a key question that has not been adequately addressed by previous studies. No study has used standardized photographs,…”
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