Search Results - "JONES, Allen N"

Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans by KOCHANSKY, Christopher J, RIPPLEY, Ronda K, FRANKLIN, Ronald B, WAGNER, John, YAN, Kerri X, HENGCHANG SONG, WALLACE, Michael A, DEAN, Dennis, JONES, Allen N, LASSETER, Kenneth, SCHWARTZ, Jules, VINCENT, Stella H

“…MK-0767 (KRP-297; 2-methoxy-5-(2,4-dioxo-5-thiazolidinyl)- N -[[4-(trifluoromethyl)phenyl] methyl]benzamide) is a thiazolidinedione (TZD)-containing dual…”
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Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans by KUMAR, Sanjeev, TAN, Eugene Y, KARANAM, Bindhu, DEAN, Dennis C, GENDRANO, Isaias Noel, GRAVES, Mark W, WAGNER, John A, KRISHNA, Rajesh, HARTMANN, Georgy, BIDDLE, Zachary, BERGMAN, Arthur J, DRU, James, HO, Jonathan Z, JONES, Allen N, STASKIEWICZ, Steve J, BRAUN, Matthew P

“…Anacetrapib is a novel cholesteryl ester transfer protein inhibitor being developed for the treatment of primary hypercholesterolemia and mixed dyslipidemia…”
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Protocols of in vitro protein covalent binding studies in liver by Lévesque, Jean-François, Day, Stephen H, Jones, Allen N

“…Xenobiotics, including therapeutic agents, can produce a variety of beneficial, as well as adverse, effects in mammals. One potential source of drug-mediated…”
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The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs by HALPIN, Rita A, GEER, Leslie A, ZHANG, Kanyin E, MARKS, Tina M, DEAN, Dennis C, JONES, Allen N, MELILLO, David, DOSS, George, VYAS, Kamlesh P

“…Absorption, distribution, metabolism, and excretion studies were conducted in rats and dogs with rofecoxib (VIOXX, MK-0966), a potent and highly selective…”
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Applications of LC-ARC™ stop-flow radiochemical detection by Schenk, David J., Ho, Jonathan Z., Simeone, Joseph P., Wallace, Michael A., Cato, Brian P., Staskiewicz, Steven J., Jones, Allen N., Melillo, David G.

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Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist by RANSOM, Richard W, HARRELL, Charles M, SU, Dai-Shi, MARKOWITZ, M. Kristine, WALLACE, Michael A, RAAB, Conrad E, JONES, Allen N, DEAN, Dennis C, PETTIBONE, Douglas J, FREIDINGER, Roger M, BOCK, Mark G, REISS, Duane R, MURPHY, Kathryn L, CHANG, Raymond S. L, HESS, J. Fred, MILLER, Patricia J, O'MALLEY, Stacey S, HEY, Pat J, KUNAPULI, Priya

“…Compound A (N-[2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl]-2-[(2R)-1-(2-napthylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]acetamide) is a member of…”
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Ultrasonic particle size reduction of radiolabeled pharmaceuticals by Schenk, David J., Jones, Allen N., Braun, Matthew P., Yao, Dan, Wallace, Michael A., Marques, Rosemary, Jenkins, Herbert J., Chang, Anson, Jia, Xiujuan, Crocker, Louis S., Dean, Dennis C., Melillo, David G.

“…High‐intensity ultrasonic treatment of MeOH/H2O, IPA/H2O, EtOH or H2O suspensions of C‐14 labeled and unlabeled pharmaceuticals successfully reduced the…”
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Synthesis of [C2H3]methotrexate and [C2H3]7-hydroxymethotrexate by Elmore, Charles S., Dean, Dennis C., Zhang, Yong, Gibson, Carter, Jenkins, Herb, Jones, Allen N., Melillo, David G.

“…Stable label analogues of methotrexate (MTX) and 7‐hydroxymethotrexate (7‐OH‐MTX) were required for use as internal standards for LC/MS quantitation. A minimum…”
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Synthesis and evaluation of furan, thiophene, and azole bis[(carbamoyloxy)methyl] derivatives as potential antineoplastic agents by Anderson, Wayne K, Jones, Allen N

“…A series of bis(hydroxymethyl)-substituted heterocycles were synthesized and converted to the corresponding bis(methylcarbamate) derivatives. The heterocyclic…”
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Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B 1 receptor antagonist by Ransom, Richard W., Harrell, Charles M., Reiss, Duane R., Murphy, Kathryn L., Chang, Raymond S.L., Hess, J. Fred, Miller, Patricia J., O'Malley, Stacey S., Hey, Pat J., Kunapuli, Priya, Su, Dai-Shi, Markowitz, M. Kristine, Wallace, Michael A., Raab, Conrad E., Jones, Allen N., Dean, Dennis C., Pettibone, Douglas J., Freidinger, Roger M., Bock, Mark G.

“…Compound A ( N-{2-[4-(4,5-dihydro-1 H-imidazol-2-yl)phenyl]ethyl}-2-[(2 R)-1-(2-napthylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]acetamide) is a member…”
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A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence by Egger, Linda A, Cao, Jin, McCallum, Christine, Kidambi, Usha, Van Riper, Gail, McCauley, Ermengilda, Mumford, Richard A, Lanza, Thomas J, Lin, Linus S, de Laszlo, Stephen E, Young, David N, Yang, Ginger, Dean, Dennis C, Raab, Conrad E, Wallace, Mike A, Jones, Allen N, Hagmann, William K, Schmidt, John A, Pepinsky, R Blake, Scott, Daniel M, Lee, Wen-Cherng, Cornebise, Mark A, Detmers, Patricia A

“…An alpha4beta1/alpha4beta7 dual antagonist, 35S-compound 1, was used as a model ligand to study the effect of divalent cations on the activation state and…”
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WOMEN FINANCIAL SECURITY by Jones, Allen N

“…  Annual financial planning surveys have consistently found that many women care about aspects of long-term financial security, including personal saving and…”
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ALTERNATIVES TO TREASURY SECURITIES by Jones, Allen N

“…  While budget surpluses may be good news for the government, the growing scarcity of Treasury securities can wreak havoc for investors who've sought the…”
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MARKET TURBULENCE? STAY ON COURSE by Jones, Allen N

“…  Jones offers suggestions for investors seeking to find the best option during the current period of market volatility. He counsels investors to keep their…”
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Money TALKS by Jones, Allen N

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EXPAND YOUR INVESTMENT HORIZONS by Jones, Allen N

“…  Merrill Lynch analysts agree this is a year to look beyond the narrow confines of the last few years--into international markets, smaller cap stocks, a…”
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Money TALKS by Jones, Allen N

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Money TALKS by Jones, Allen N

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Financial reform's results by Jones, Allen N

“…  Jones explains how consumers of financial services will benefit from the Financial Services Modernization Act of 1999. The Treasury Department estimates the…”
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