Search Results - "JOLOBA, Moses"

Evaluation of circulating serum cathelicidin levels as a potential biomarker to discriminate between active and latent tuberculosis in Uganda by Acen, Ester Lilian, Kateete, David Patrick, Worodria, William, Olum, Ronald, Joloba, Moses L, Bbuye, Mudarshiru, Biraro, Irene Andia

“…Tuberculosis remains a major public health problem worldwide accounting for 1.4 million deaths annually. LL-37 is an effector molecule involved in immunity…”
Get full text

Impact of vitamin D status and cathelicidin antimicrobial peptide on adults with active pulmonary TB globally: A systematic review and meta-analysis by Acen, Ester Lilian, Biraro, Irene Andia, Worodria, William, Joloba, Moses L, Nkeeto, Bill, Musaazi, Joseph, Kateete, David Patrick

“…Background Tuberculosis remains a global threat and a public health problem that has eluded attempts to eradicate it. Low vitamin D levels have been identified…”
Get full text

Evaluation of Xpert MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second-line drugs in Uganda by Katamba, Achilles, Ssengooba, Willy, Sserubiri, James, Semugenze, Derrick, Kasule, George William, Nyombi, Abdunoor, Byaruhanga, Raymond, Turyahabwe, Stavia, Joloba, Moses L

“…Background Drug-Resistant Tuberculosis (DR-TB) is one of the major challenges to TB control. Design and methods This was a blinded, laboratory-based…”
Get full text

Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda by Kigozi, Edgar, Kasule, George W, Musisi, Kenneth, Lukoye, Deus, Kyobe, Samuel, Katabazi, Fred Ashaba, Wampande, Eddie M, Joloba, Moses L, Kateete, David Patrick

“…Accurate diagnosis of tuberculosis, especially by using rapid molecular assays, can reduce transmission of drug resistant tuberculosis in communities. However,…”
Get full text

HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa by Windels, Etthel M, Wampande, Eddie M, Joloba, Moses L, Boom, W Henry, Goig, Galo A, Cox, Helen, Hella, Jerry, Borrell, Sonia, Gagneux, Sebastien, Brites, Daniela, Stadler, Tanja

“…Persons living with HIV are known to be at increased risk of developing tuberculosis (TB) disease upon infection with Mycobacterium tuberculosis (Mtb)…”
Get full text

Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis by Bwanga, Freddie, Hoffner, Sven, Haile, Melles, Joloba, Moses L

“…One of the challenges facing the tuberculosis (TB) control programmes in resource-limited settings is lack of rapid techniques for detection of drug resistant…”
Get full text

Identification of Staphylococcus aureus: DNase and Mannitol salt agar improve the efficiency of the tube coagulase test by Kateete, David P, Kimani, Cyrus N, Katabazi, Fred A, Okeng, Alfred, Okee, Moses S, Nanteza, Ann, Joloba, Moses L, Najjuka, Florence C

“…The ideal identification of Staphylococcus aureus clinical isolates requires a battery of tests and this is costly in resource limited settings. In many…”
Get full text

Performance evaluation of Truenat MTB and Truenat MTB-RIF DX assays in comparison to gene XPERT MTB/RIF ultra for the diagnosis of pulmonary tuberculosis in Uganda by Ssengooba, Willy, Katamba, Achilles, Sserubiri, James, Semugenze, Derrick, Nyombi, Abdunoor, Byaruhanga, Raymond, Turyahabwe, Stavia, Joloba, Moses L

“…The World Health Organization endorsed Truenat MTB rapid molecular assay in 2020 and recommended additional in-country evaluation studies before uptake. We…”
Get full text

Monocyte Dysfunction, Activation, and Inflammation After Long-Term Antiretroviral Therapy in an African Cohort by Nabatanzi, Rose, Bayigga, Lois, Cose, Stephen, Rowland Jones, Sarah, Joloba, Moses, Canderan, Glenda, Nakanjako, Damalie

“…Monocyte dysfunction may persist during antiretroviral therapy (ART). Frozen peripheral blood mononuclear cells of 30 human immunodeficiency virus…”
Get full text

Anti-tuberculosis drug resistance among new and previously treated sputum smear-positive tuberculosis patients in Uganda: results of the first national survey by Lukoye, Deus, Adatu, Francis, Musisi, Kenneth, Kasule, George William, Were, Willy, Odeke, Rosemary, Kalamya, Julius Namonyo, Awor, Ann, Date, Anand, Joloba, Moses L

“…Multidrug resistant and extensively drug resistant tuberculosis (TB) have become major threats to control of tuberculosis globally. The rates of anti-TB drug…”
Get full text

Hypovitaminosis D among newly diagnosed pulmonary TB patients and their household contacts in Uganda by Acen, Ester Lilian, Biraro, Irene Andia, Bbuye, Mudarshiru, Kateete, David Patrick, Joloba, Moses L., Worodria, William

“…An estimated one billion people globally live with hypovitaminosis D. Studies have indicated that vitamin D deficiency is a risk factor for active tuberculosis…”
Get full text

Endothelial Activation, Acute Kidney Injury, and Cognitive Impairment in Pediatric Severe Malaria by Ouma, Benson J., Ssenkusu, John M., Shabani, Estela, Datta, Dibyadyuti, Opoka, Robert O., Idro, Richard, Bangirana, Paul, Park, Gregory, Joloba, Moses L., Kain, Kevin C., John, Chandy C., Conroy, Andrea L.

“…OBJECTIVES:Evaluate the relationship between endothelial activation, malaria complications, and long-term cognitive outcomes in severe malaria survivors…”
Get full text

Resistance and Susceptibility to Mycobacterium tuberculosis Infection and Disease in Tuberculosis Households in Kampala, Uganda by Stein, Catherine M, Zalwango, Sarah, Malone, LaShaunda L, Thiel, Bonnie, Mupere, Ezekiel, Nsereko, Mary, Okware, Brenda, Kisingo, Hussein, Lancioni, Christina L, Bark, Charles M, Whalen, Christopher C, Joloba, Moses L, Boom, W Henry, Mayanja-Kizza, Harriet

“…Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a major public health problem. Household contact studies identify children and…”
Get full text

Evaluation of the Xpert MTB/RIF test for the diagnosis of childhood pulmonary tuberculosis in Uganda: a cross-sectional diagnostic study by Sekadde, Moorine Penninah, Wobudeya, Eric, Joloba, Moses L, Ssengooba, Willy, Kisembo, Harriet, Bakeera-Kitaka, Sabrina, Musoke, Philippa

“…The diagnosis of childhood tuberculosis remains a challenge worldwide. The Xpert MTB/RIF test, a rapid mycobacteria tuberculosis diagnostic tool, was…”
Get full text

Agreement of Middle brook 7H10 with Lowenstein Jensen and accuracy of the Sensititre MYCOTB plate using either method as a reference standard for Mycobacterium tuberculosis first line drug susceptibility testing by Ssengooba, Willy, Nakayita, Germine, Namaganda, Carolyn C, Joloba, Moses L

“…Although Sensititre Mycobacterium tuberculosis (MYCOTB) plate offers both drug susceptibility testing (DST) and minimum inhibitory concentration (MIC) results,…”
Get full text

Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda by Wampande, Eddie M, Naniima, Peter, Mupere, Ezekiel, Kateete, David P, Malone, LaShaunda L, Stein, Catherine M, Mayanja-Kizza, Harriet, Gagneux, Sebastien, Boom, W Henry, Joloba, Moses L

“…Limited data existed exclusively describing Mycobacterium tuberculosis lineage 3 (MTB-L3), sub-lineages, and clinical manifestations in Kampala, Uganda. This…”
Get full text

Prevalence of Tuberculosis Risk Factors among Bacteriologically Negative and Bacteriologically Confirmed Tuberculosis Patients from Five Regional Referral Hospitals in Uganda by Muttamba, Winters, Kirenga, Bruce, Ssengooba, Willy, Sekibira, Rogers, Katamba, Achilles, Joloba, Moses L

“…Understanding risk factors for tuberculosis (TB) and their prevalence helps guide early diagnosis. We determined their prevalence among bacteriologically…”
Get full text

Bioinformatics mentorship in a resource limited setting by Jjingo, Daudi, Mboowa, Gerald, Sserwadda, Ivan, Kakaire, Robert, Kiberu, Davis, Amujal, Marion, Galiwango, Ronald, Kateete, David, Joloba, Moses, Whalen, Christopher C

“…Abstract Background The two recent simultaneous developments of high-throughput sequencing and increased computational power have brought bioinformatics to the…”
Get full text

Implementation of GeneXpert MTB/Rif proficiency testing program: A Case of the Uganda national tuberculosis reference laboratory/supranational reference laboratory by Kabugo, Joel, Namutebi, Joanita, Mujuni, Dennis, Nsawotebba, Andrew, Kasule, George William, Musisi, Kenneth, Kigozi, Edgar, Nyombi, Abdunoor, Lutaaya, Pius, Kangave, Fredrick, Joloba, Moses L

“…Following the WHO's endorsement of GeneXpert MTB/RIF assay for tuberculosis diagnosis in 2010, Uganda's ministry of health introduced the assay in its…”
Get full text

Genomic characterization of SARS-CoV-2 from Uganda using MinION nanopore sequencing by Kia, Praiscillia, Katagirya, Eric, Kakembo, Fredrick Elishama, Adera, Doreen Ato, Nsubuga, Moses Luutu, Yiga, Fahim, Aloyo, Sharley Melissa, Aujat, Brendah Ronah, Anguyo, Denis Foe, Katabazi, Fred Ashaba, Kigozi, Edgar, Joloba, Moses L., Kateete, David Patrick

“…SARS-CoV-2 undergoes frequent mutations, affecting COVID-19 diagnostics, transmission and vaccine efficacy. Here, we describe the genetic diversity of 49…”
Get full text